Gene Card
Best human hits
MYLK; MYLK4; TTN
Species
Unique Gene ID
Moocul.g00014754
Gene Model ID
Moocul.CG.ELv1_2.S126332.g14754
Location
S126332:54386..63216
Transcript Models and Sequences
n/a
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Click here to see the tree inference method
InterPro
20 results
| IPR Term | Analysis | Definition |
|---|---|---|
| FN3_dom | Pfam | Fibronectin type III |
| Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
| Ig-like_dom_sf | SUPERFAMILY | Immunoglobulin-like domain superfamily |
| Ig_sub2 | SMART | Immunoglobulin subtype 2 |
| Ig-like_fold | Gene3D | Immunoglobulin-like fold |
| Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
| Prot_kinase_dom | SMART | Protein kinase domain |
| Ig-like_dom | ProSiteProfiles | Immunoglobulin-like domain |
| Znf_FYVE_PHD | SUPERFAMILY | Zinc finger, FYVE/PHD-type |
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| FN3_dom | SMART | Fibronectin type III |
| Rab_BD | ProSiteProfiles | Rab-binding domain |
| Prot_kinase_dom | Pfam | Protein kinase domain |
| Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
| Ig_I-set | Pfam | Immunoglobulin I-set |
| FN3_dom | CDD | Fibronectin type III |
| FN3_dom | ProSiteProfiles | Fibronectin type III |
| FN3_sf | SUPERFAMILY | Fibronectin type III superfamily |
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| Ig_sub | SMART | Immunoglobulin subtype |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
48 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| nucleotide binding | Hs | molecular function |
| stress fiber | Hs | cellular component |
| actin binding | Hs | molecular function |
| protein kinase activity | Hs | molecular function |
| protein serine/threonine kinase activity | Hs | molecular function |
| myosin light chain kinase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| calmodulin binding | Hs | molecular function |
| ATP binding | Hs | molecular function |
| intracellular | Hs | cellular component |
| nucleus | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| cytosol | Hs | cellular component |
| cytoskeleton | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| protein phosphorylation | Hs | biological process |
| muscle contraction | Hs | biological process |
| smooth muscle contraction | Hs | biological process |
| striated muscle contraction | Hs | biological process |
| positive regulation of gene expression | Hs | biological process |
| actin cytoskeleton | Hs | cellular component |
| kinase activity | Hs | molecular function |
| phosphorylation | Hs | biological process |
| transferase activity | Hs | molecular function |
| peptidyl-serine phosphorylation | Hs | biological process |
| peptidyl-threonine phosphorylation | Hs | biological process |
| lamellipodium | Hs | cellular component |
| positive regulation of cell migration | Hs | biological process |
| bleb assembly | Hs | biological process |
| cleavage furrow | Hs | cellular component |
| intracellular signal transduction | Hs | biological process |
| cell projection | Hs | cellular component |
| sarcomere organization | Hs | biological process |
| metal ion binding | Hs | molecular function |
| positive regulation of calcium ion transport | Hs | biological process |
| cardiac myofibril assembly | Hs | biological process |
| cardiac muscle tissue morphogenesis | Hs | biological process |
| cardiac muscle contraction | Hs | biological process |
| extracellular exosome | Hs | cellular component |
| cellular hypotonic response | Hs | biological process |
| positive regulation of wound healing | Hs | biological process |
| calmodulin-dependent protein kinase activity | Hs | molecular function |
| neuromuscular synaptic transmission | Hs | biological process |
| sarcomere | Hs | cellular component |
| skeletal muscle cell differentiation | Hs | biological process |
| protein autophosphorylation | Hs | biological process |
| positive regulation of sarcomere organization | Hs | biological process |
| cellular response to interleukin-1 | Hs | biological process |
GO (Blast)
42 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 677 | 0.0 |
| condensed nuclear chromosome | Hs | cellular component | 365 | 5.10e-103 |
| stress fiber | Hs | cellular component | 677 | 0.0 |
| protease binding | Hs | molecular function | 365 | 5.10e-103 |
| actin binding | Hs | molecular function | 677 | 0.0 |
| protein kinase activity | Hs | molecular function | 677 | 0.0 |
| protein serine/threonine kinase activity | Hs | molecular function | 677 | 0.0 |
| myosin light chain kinase activity | Hs | molecular function | 677 | 0.0 |
| protein tyrosine kinase activity | Hs | molecular function | 365 | 5.10e-103 |
| calcium ion binding | Hs | molecular function | 365 | 5.10e-103 |
| protein binding | Hs | molecular function | 677 | 0.0 |
| calmodulin binding | Hs | molecular function | 677 | 0.0 |
| ATP binding | Hs | molecular function | 677 | 0.0 |
| extracellular region | Hs | cellular component | 365 | 5.10e-103 |
| intracellular | Hs | cellular component | 325 | 7.99e-100 |
| nucleus | Hs | cellular component | 365 | 5.10e-103 |
| cytoplasm | Hs | cellular component | 677 | 0.0 |
| cytosol | Hs | cellular component | 677 | 0.0 |
| cytoskeleton | Hs | cellular component | 677 | 0.0 |
| muscle myosin complex | Hs | cellular component | 365 | 5.10e-103 |
| plasma membrane | Hs | cellular component | 677 | 0.0 |
| structural constituent of muscle | Hs | molecular function | 365 | 5.10e-103 |
| actin cytoskeleton | Hs | cellular component | 677 | 0.0 |
| kinase activity | Hs | molecular function | 677 | 0.0 |
| transferase activity | Hs | molecular function | 677 | 0.0 |
| enzyme binding | Hs | molecular function | 365 | 5.10e-103 |
| protein kinase binding | Hs | molecular function | 365 | 5.10e-103 |
| Z disc | Hs | cellular component | 365 | 5.10e-103 |
| lamellipodium | Hs | cellular component | 677 | 0.0 |
| M band | Hs | cellular component | 365 | 5.10e-103 |
| telethonin binding | Hs | molecular function | 365 | 5.10e-103 |
| I band | Hs | cellular component | 365 | 5.10e-103 |
| cleavage furrow | Hs | cellular component | 677 | 0.0 |
| identical protein binding | Hs | molecular function | 365 | 5.10e-103 |
| actinin binding | Hs | molecular function | 365 | 5.10e-103 |
| cell projection | Hs | cellular component | 677 | 0.0 |
| protein self-association | Hs | molecular function | 365 | 5.10e-103 |
| metal ion binding | Hs | molecular function | 677 | 0.0 |
| actin filament binding | Hs | molecular function | 365 | 5.10e-103 |
| muscle alpha-actinin binding | Hs | molecular function | 365 | 5.10e-103 |
| extracellular exosome | Hs | cellular component | 677 | 0.0 |
| structural molecule activity conferring elasticity | Hs | molecular function | 365 | 5.10e-103 |
GO (InterProScan)
6 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | SMART | molecular function | 4.9E-93 |
| protein binding | SUPERFAMILY | molecular function | 5.9E-25 |
| ATP binding | SMART | molecular function | 4.9E-93 |
| protein phosphorylation | SMART | biological process | 4.9E-93 |
| intracellular protein transport | ProSiteProfiles | biological process | 8.656 |
| Rab GTPase binding | ProSiteProfiles | molecular function | 8.656 |
