Gene Card
Best human hits
TP53; TP63; TP73
Species
Unique Gene ID
Moocul.g00014485
Gene Model ID
Moocul.CG.ELv1_2.S123527.g14485
Location
S123527:2376..12367
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
9 results
| IPR Term | Analysis | Definition |
|---|---|---|
| p53_tetrameristn | Pfam | p53, tetramerisation domain |
| p53_tetramer_sf | Gene3D | p53-like tetramerisation domain superfamily |
| p53_tumour_suppressor | PRINTS | p53 tumour suppressor family |
| p53_tetramer_sf | SUPERFAMILY | p53-like tetramerisation domain superfamily |
| p53/RUNT-type_TF_DNA-bd_sf | Gene3D | p53/RUNT-type transcription factor, DNA-binding domain superfamily |
| p53_tumour_suppressor | PANTHER | p53 tumour suppressor family |
| p53-like_TF_DNA-bd | SUPERFAMILY | p53-like transcription factor, DNA-binding |
| p53_DNA-bd | CDD | p53, DNA-binding domain |
| p53_DNA-bd | Pfam | p53, DNA-binding domain |
| GO Term | Annotation Origin | Type |
|---|
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
70 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| chromatin | Hs | cellular component | 189 | 1.58e-53 |
| nuclear chromatin | Hs | cellular component | 191 | 6.60e-54 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 189 | 1.58e-53 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 191 | 6.60e-54 |
| transcription factor activity, transcription factor binding | Hs | molecular function | 191 | 6.60e-54 |
| transcription factor activity, core RNA polymerase binding | Hs | molecular function | 159 | 4.37e-44 |
| core promoter sequence-specific DNA binding | Hs | molecular function | 159 | 4.37e-44 |
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly | Hs | molecular function | 159 | 4.37e-44 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | Hs | molecular function | 191 | 6.60e-54 |
| transcription factor activity, TFIID-class binding | Hs | molecular function | 159 | 4.37e-44 |
| RNA polymerase II transcription factor binding | Hs | molecular function | 159 | 4.37e-44 |
| TFIID-class transcription factor binding | Hs | molecular function | 159 | 4.37e-44 |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | Hs | molecular function | 159 | 4.37e-44 |
| protease binding | Hs | molecular function | 159 | 4.37e-44 |
| p53 binding | Hs | molecular function | 191 | 6.60e-54 |
| DNA binding | Hs | molecular function | 191 | 6.60e-54 |
| chromatin binding | Hs | molecular function | 191 | 6.60e-54 |
| damaged DNA binding | Hs | molecular function | 191 | 6.60e-54 |
| double-stranded DNA binding | Hs | molecular function | 191 | 6.60e-54 |
| transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 191 | 6.60e-54 |
| mRNA 3'-UTR binding | Hs | molecular function | 159 | 4.37e-44 |
| copper ion binding | Hs | molecular function | 159 | 4.37e-44 |
| protein binding | Hs | molecular function | 191 | 6.60e-54 |
| ATP binding | Hs | molecular function | 159 | 4.37e-44 |
| intracellular | Hs | cellular component | 159 | 4.37e-44 |
| nucleus | Hs | cellular component | 191 | 6.60e-54 |
| nucleoplasm | Hs | cellular component | 191 | 6.60e-54 |
| replication fork | Hs | cellular component | 159 | 4.37e-44 |
| transcription factor complex | Hs | cellular component | 191 | 6.60e-54 |
| transcription factor TFIID complex | Hs | cellular component | 159 | 4.37e-44 |
| nucleolus | Hs | cellular component | 159 | 4.37e-44 |
| cytoplasm | Hs | cellular component | 191 | 6.60e-54 |
| mitochondrion | Hs | cellular component | 191 | 6.60e-54 |
| mitochondrial matrix | Hs | cellular component | 159 | 4.37e-44 |
| endoplasmic reticulum | Hs | cellular component | 159 | 4.37e-44 |
| rough endoplasmic reticulum | Hs | cellular component | 191 | 6.60e-54 |
| Golgi apparatus | Hs | cellular component | 191 | 6.60e-54 |
| cytosol | Hs | cellular component | 191 | 6.60e-54 |
| transcription factor binding | Hs | molecular function | 189 | 1.58e-53 |
| zinc ion binding | Hs | molecular function | 159 | 4.37e-44 |
| membrane | Hs | cellular component | 159 | 4.37e-44 |
| integral component of membrane | Hs | cellular component | 159 | 4.37e-44 |
| nuclear matrix | Hs | cellular component | 159 | 4.37e-44 |
| nuclear body | Hs | cellular component | 159 | 4.37e-44 |
| PML body | Hs | cellular component | 159 | 4.37e-44 |
| enzyme binding | Hs | molecular function | 159 | 4.37e-44 |
| protein kinase binding | Hs | molecular function | 189 | 1.58e-53 |
| protein phosphatase binding | Hs | molecular function | 159 | 4.37e-44 |
| protein domain specific binding | Hs | molecular function | 191 | 6.60e-54 |
| cell junction | Hs | cellular component | 189 | 1.58e-53 |
| dendrite | Hs | cellular component | 191 | 6.60e-54 |
| receptor tyrosine kinase binding | Hs | molecular function | 159 | 4.37e-44 |
| ubiquitin protein ligase binding | Hs | molecular function | 159 | 4.37e-44 |
| macromolecular complex | Hs | cellular component | 159 | 4.37e-44 |
| histone acetyltransferase binding | Hs | molecular function | 159 | 4.37e-44 |
| identical protein binding | Hs | molecular function | 191 | 6.60e-54 |
| histone deacetylase binding | Hs | molecular function | 159 | 4.37e-44 |
| neuron projection | Hs | cellular component | 191 | 6.60e-54 |
| intracellular membrane-bounded organelle | Hs | cellular component | 189 | 1.58e-53 |
| sequence-specific DNA binding | Hs | molecular function | 191 | 6.60e-54 |
| protein self-association | Hs | molecular function | 159 | 4.37e-44 |
| transcription regulatory region DNA binding | Hs | molecular function | 191 | 6.60e-54 |
| metal ion binding | Hs | molecular function | 191 | 6.60e-54 |
| protein heterodimerization activity | Hs | molecular function | 159 | 4.37e-44 |
| protein N-terminus binding | Hs | molecular function | 159 | 4.37e-44 |
| WW domain binding | Hs | molecular function | 191 | 6.60e-54 |
| chaperone binding | Hs | molecular function | 159 | 4.37e-44 |
| protein phosphatase 2A binding | Hs | molecular function | 159 | 4.37e-44 |
| MDM2/MDM4 family protein binding | Hs | molecular function | 191 | 6.60e-54 |
| disordered domain specific binding | Hs | molecular function | 159 | 4.37e-44 |
GO (InterProScan)
7 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| DNA binding | PANTHER | molecular function | 1.3E-87 |
| transcription factor activity, sequence-specific DNA binding | PANTHER | molecular function | 1.3E-87 |
| nucleus | PANTHER | cellular component | 1.3E-87 |
| regulation of transcription, DNA-templated | PANTHER | biological process | 1.3E-87 |
| apoptotic process | PANTHER | biological process | 1.3E-87 |
| transcription regulatory region DNA binding | CDD | molecular function | 1.68326E-73 |
| protein tetramerization | Gene3D | biological process | 1.4E-10 |
