Gene Card
Best human hits
AFG3L2; SPG7; YME1L1
Species
Unique Gene ID
Moocul.g00011549
Gene Model ID
Moocul.CG.ELv1_2.S110215.g11549
Location
S110215:2153..4208
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
7 results
| IPR Term | Analysis | Definition |
|---|---|---|
| AAA+_ATPase | SMART | AAA+ ATPase domain |
| Peptidase_M41-like | SUPERFAMILY | Peptidase M41-like |
| ATPase_AAA_CS | ProSitePatterns | ATPase, AAA-type, conserved site |
| P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
| ATPase_AAA_core | Pfam | ATPase, AAA-type, core |
| Peptidase_M41 | Pfam | Peptidase M41 |
| FtsH | TIGRFAM | Peptidase, FtsH |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
22 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| nucleotide binding | Hs | molecular function |
| ATP-dependent peptidase activity | Hs | molecular function |
| metalloendopeptidase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| ATP binding | Hs | molecular function |
| mitochondrion | Hs | cellular component |
| mitochondrial inner membrane | Hs | cellular component |
| proteolysis | Hs | biological process |
| protein quality control for misfolded or incompletely synthesized proteins | Hs | biological process |
| mitochondrial calcium ion transmembrane transport | Hs | biological process |
| mitochondrion organization | Hs | biological process |
| peptidase activity | Hs | molecular function |
| metallopeptidase activity | Hs | molecular function |
| cell proliferation | Hs | biological process |
| membrane | Hs | cellular component |
| integral component of membrane | Hs | cellular component |
| nuclear body | Hs | cellular component |
| hydrolase activity | Hs | molecular function |
| protein hexamerization | Hs | biological process |
| mitochondrial protein catabolic process | Hs | biological process |
| negative regulation of apoptotic process | Hs | biological process |
| metal ion binding | Hs | molecular function |
GO (Blast)
19 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 484 | 6.19e-162 |
| ATP-dependent peptidase activity | Hs | molecular function | 484 | 6.19e-162 |
| metalloendopeptidase activity | Hs | molecular function | 484 | 6.19e-162 |
| protein binding | Hs | molecular function | 484 | 6.19e-162 |
| ATP binding | Hs | molecular function | 484 | 6.19e-162 |
| mitochondrion | Hs | cellular component | 484 | 6.19e-162 |
| mitochondrial inner membrane | Hs | cellular component | 484 | 6.19e-162 |
| m-AAA complex | Hs | cellular component | 350 | 7.53e-110 |
| mitochondrial permeability transition pore complex | Hs | cellular component | 314 | 1.86e-96 |
| peptidase activity | Hs | molecular function | 484 | 6.19e-162 |
| metallopeptidase activity | Hs | molecular function | 484 | 6.19e-162 |
| zinc ion binding | Hs | molecular function | 350 | 7.53e-110 |
| membrane | Hs | cellular component | 484 | 6.19e-162 |
| integral component of membrane | Hs | cellular component | 484 | 6.19e-162 |
| nuclear body | Hs | cellular component | 484 | 6.19e-162 |
| hydrolase activity | Hs | molecular function | 484 | 6.19e-162 |
| metal ion binding | Hs | molecular function | 484 | 6.19e-162 |
| unfolded protein binding | Hs | molecular function | 350 | 7.53e-110 |
| axon cytoplasm | Hs | cellular component | 314 | 1.86e-96 |
GO (InterProScan)
4 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| metalloendopeptidase activity | TIGRFAM | molecular function | 3.4E-159 |
| ATP binding | SUPERFAMILY | molecular function | 4.32E-52 |
| proteolysis | SUPERFAMILY | biological process | 4.32E-52 |
| membrane | TIGRFAM | cellular component | 3.4E-159 |
