Gene Card
Best human hits
ACVR1; ACVR1C; TGFBR1
Species
Unique Gene ID
Moocci.g00005423
Gene Model ID
Moocci.CG.ELv1_2.S240389.g05423
Location
S240389:57419..60600
Transcript Models and Sequences
Moocci.CG.ELv1_2.S240389.g05423.01.t
Moocci.CG.ELv1_2.S240389.g05423.02.t
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Prot_kinase_dom | Pfam | Protein kinase domain |
GS_dom | Pfam | GS domain |
GS_dom | ProSiteProfiles | GS domain |
TGFB_receptor | PANTHER | Ser/Thr protein kinase, TGFB receptor |
GS_dom | SMART | GS domain |
Activin_recp | Pfam | Activin types I and II receptor domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 340 | 4.27e-112 |
protein kinase activity | Hs | molecular function | 340 | 4.27e-112 |
protein serine/threonine kinase activity | Hs | molecular function | 340 | 4.27e-112 |
transmembrane receptor protein serine/threonine kinase activity | Hs | molecular function | 340 | 4.27e-112 |
signal transducer, downstream of receptor, with serine/threonine kinase activity | Hs | molecular function | 340 | 4.27e-112 |
transforming growth factor beta-activated receptor activity | Hs | molecular function | 340 | 4.27e-112 |
transforming growth factor beta receptor activity, type I | Hs | molecular function | 340 | 4.27e-112 |
signal transducer activity, downstream of receptor | Hs | molecular function | 340 | 4.27e-112 |
receptor binding | Hs | molecular function | 340 | 4.27e-112 |
type II transforming growth factor beta receptor binding | Hs | molecular function | 340 | 4.27e-112 |
protein binding | Hs | molecular function | 340 | 4.27e-112 |
ATP binding | Hs | molecular function | 340 | 4.27e-112 |
cell | Hs | cellular component | 340 | 4.27e-112 |
endosome | Hs | cellular component | 340 | 4.27e-112 |
plasma membrane | Hs | cellular component | 340 | 4.27e-112 |
integral component of plasma membrane | Hs | cellular component | 306 | 9.22e-99 |
bicellular tight junction | Hs | cellular component | 340 | 4.27e-112 |
cell surface | Hs | cellular component | 340 | 4.27e-112 |
membrane | Hs | cellular component | 340 | 4.27e-112 |
integral component of membrane | Hs | cellular component | 340 | 4.27e-112 |
kinase activity | Hs | molecular function | 340 | 4.27e-112 |
activin receptor activity, type I | Hs | molecular function | 309 | 3.24e-100 |
transferase activity | Hs | molecular function | 340 | 4.27e-112 |
peptide hormone binding | Hs | molecular function | 306 | 9.22e-99 |
growth factor binding | Hs | molecular function | 340 | 4.27e-112 |
cell junction | Hs | cellular component | 340 | 4.27e-112 |
nodal binding | Hs | molecular function | 309 | 3.24e-100 |
protein homodimerization activity | Hs | molecular function | 306 | 9.22e-99 |
intracellular membrane-bounded organelle | Hs | cellular component | 340 | 4.27e-112 |
receptor complex | Hs | cellular component | 340 | 4.27e-112 |
membrane raft | Hs | cellular component | 340 | 4.27e-112 |
apical part of cell | Hs | cellular component | 306 | 9.22e-99 |
SMAD binding | Hs | molecular function | 340 | 4.27e-112 |
metal ion binding | Hs | molecular function | 340 | 4.27e-112 |
activin receptor complex | Hs | cellular component | 309 | 3.24e-100 |
activin binding | Hs | molecular function | 306 | 9.22e-99 |
transforming growth factor beta binding | Hs | molecular function | 340 | 4.27e-112 |
transforming growth factor beta receptor complex | Hs | cellular component | 340 | 4.27e-112 |
I-SMAD binding | Hs | molecular function | 340 | 4.27e-112 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 1.8E-12 |
transmembrane receptor protein serine/threonine kinase activity | Pfam | molecular function | 3.1E-12 |
signal transducer, downstream of receptor, with serine/threonine kinase activity | PANTHER | molecular function | 6.7E-135 |
ATP binding | PANTHER | molecular function | 6.7E-135 |
protein phosphorylation | Pfam | biological process | 1.8E-12 |
transmembrane receptor protein serine/threonine kinase signaling pathway | PANTHER | biological process | 6.7E-135 |
membrane | PANTHER | cellular component | 6.7E-135 |