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GENE CARD

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Gene Card

Best human hits

CTGF; CYR61; WISP1

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00014344

Gene Model ID

KH2012:KH.S346.6

Location

KhS346:52383..58010

Transcript Models and Sequences

  KH2012:KH.S346.6.v1.A.ND1-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000005383
NCBI Reference Sequence XM_002127121.3
NCBI Reference Sequence XM_018816885.1
Collections

Gateway full ORF

1 result

cima81699

Plate: VES56_M09

Gene collection 1 (N. Satoh)

1 result

cilv021c01

Plate: R1CiGC26h16

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
Growth_fac_rcpt_cys_sf SUPERFAMILY Growth factor receptor cysteine-rich domain superfamily
VWF_dom ProSiteProfiles VWFC domain
IGFBP-like ProSiteProfiles Insulin-like growth factor-binding protein, IGFBP
TSP1_rpt_sf SUPERFAMILY Thrombospondin type-1 (TSP1) repeat superfamily
Cys_knot_C ProSiteProfiles Cystine knot, C-terminal
IGFBP-like SMART Insulin-like growth factor-binding protein, IGFBP
Glyco_hormone_CN Pfam Glycoprotein hormone subunit beta
TSP1_rpt_sf Gene3D Thrombospondin type-1 (TSP1) repeat superfamily
VWF_dom SMART VWFC domain
VWF_dom Pfam VWFC domain
TSP1_rpt ProSiteProfiles Thrombospondin type-1 (TSP1) repeat
Cys_knot_C SMART Cystine knot, C-terminal
Cys_knot_C ProSitePatterns Cystine knot, C-terminal
IGFBP-like Pfam Insulin-like growth factor-binding protein, IGFBP

GOSlim

79 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
angiogenesis Orthology biological process
integrin binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
endoplasmic reticulum lumen Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
transcription initiation from RNA polymerase II promoter Orthology biological process
chemotaxis Orthology biological process
cell adhesion Orthology biological process
signal transduction Orthology biological process
cell-cell signaling Orthology biological process
protein C-terminus binding Orthology molecular function
cell proliferation Orthology biological process
positive regulation of cell proliferation Orthology biological process
response to wounding Orthology biological process
anatomical structure morphogenesis Orthology biological process
positive regulation of gene expression Orthology biological process
negative regulation of gene expression Orthology biological process
positive regulation of cell death Orthology biological process
cell migration Orthology biological process
cell differentiation Orthology biological process
extracellular matrix organization Orthology biological process
intracellular signal transduction Orthology biological process
positive regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
perinuclear region of cytoplasm Orthology cellular component
negative regulation of cell death Orthology biological process
cytoplasm Orthology cellular component
endoplasmic reticulum Orthology cellular component
regulation of gene expression Orthology biological process
cell junction Orthology cellular component
axon Orthology cellular component
neuronal cell body Orthology cellular component
intracellular membrane-bounded organelle Orthology cellular component
extracellular exosome Orthology cellular component
animal organ development Orthology biological process
cellular component organization Orthology biological process
protein phosphorylation Orthology biological process
heart development Orthology biological process
Golgi apparatus part Orthology cellular component
cell periphery Orthology cellular component
cytoplasmic part Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
developmental process Orthology biological process
receptor binding Orthology molecular function
molecular function regulator Orthology molecular function
regulation of signal transduction Orthology biological process
signaling receptor activity Orthology molecular function
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
cellular response to organic substance Orthology biological process
anatomical structure development Orthology biological process
response to organic substance Orthology biological process
regulation of molecular function Orthology biological process
organic substance metabolic process Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
positive regulation of signal transduction Orthology biological process
extracellular region part Orthology cellular component
response to lipid Orthology biological process
endopeptidase activity Orthology molecular function
positive regulation of hydrolase activity Orthology biological process
cellular protein modification process Orthology biological process
wound healing Orthology biological process
positive regulation of catalytic activity Orthology biological process
protein kinase activity Orthology molecular function
cellular response to stress Orthology biological process
binding Orthology molecular function
organelle organization Orthology biological process
regulation of cellular metabolic process Orthology biological process
DNA metabolic process Orthology biological process
cellular metabolic process Orthology biological process
amide biosynthetic process Orthology biological process
Notch signaling pathway Orthology biological process
protein transport Orthology biological process
defense response Orthology biological process

GO (Orthology)

105 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
cartilage condensation Hs biological process
ossification Hs biological process
angiogenesis Hs biological process
regulation of cell growth Hs biological process
osteoblast differentiation Hs biological process
tissue homeostasis Hs biological process
positive regulation of protein phosphorylation Hs biological process
fibronectin binding Hs molecular function
atrioventricular valve morphogenesis Hs biological process
integrin binding Hs molecular function
protein binding Hs molecular function
insulin-like growth factor binding Hs molecular function
extracellular region Hs cellular component
proteinaceous extracellular matrix Hs cellular component
extracellular space Hs cellular component
endoplasmic reticulum lumen Hs cellular component
cis-Golgi network Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
cell cortex Hs cellular component
transcription initiation from RNA polymerase II promoter Hs biological process
chemotaxis Hs biological process
cell adhesion Hs biological process
cell-matrix adhesion Hs biological process
signal transduction Hs biological process
integrin-mediated signaling pathway Hs biological process
cell-cell signaling Hs biological process
aging Hs biological process
protein C-terminus binding Hs molecular function
growth factor activity Hs molecular function
heparin binding Hs molecular function
cell proliferation Hs biological process
positive regulation of cell proliferation Hs biological process
fibroblast growth factor receptor signaling pathway Hs biological process
epidermis development Hs biological process
response to wounding Hs biological process
anatomical structure morphogenesis Hs biological process
response to glucose Hs biological process
regulation of receptor activity Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
positive regulation of cell-substrate adhesion Hs biological process
positive regulation of cell death Hs biological process
response to organic cyclic compound Hs biological process
Wnt signaling pathway Hs biological process
cell migration Hs biological process
regulation of lipid metabolic process Hs biological process
growth factor binding Hs molecular function
cell differentiation Hs biological process
extracellular matrix organization Hs biological process
lung development Hs biological process
positive regulation of cell migration Hs biological process
positive regulation of BMP signaling pathway Hs biological process
extracellular matrix Hs cellular component
regulation of chondrocyte differentiation Hs biological process
response to estradiol Hs biological process
intracellular signal transduction Hs biological process
chondrocyte proliferation Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
response to amino acid Hs biological process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
response to peptide hormone Hs biological process
post-translational protein modification Hs biological process
wound healing, spreading of cells Hs biological process
positive regulation of cell differentiation Hs biological process
positive regulation of osteoblast differentiation Hs biological process
positive regulation of protein kinase activity Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
positive regulation of JNK cascade Hs biological process
perinuclear region of cytoplasm Hs cellular component
extracellular matrix binding Hs molecular function
positive regulation of stress fiber assembly Hs biological process
negative regulation of cell death Hs biological process
positive regulation of cartilage development Hs biological process
regulation of ERK1 and ERK2 cascade Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
DNA biosynthetic process Hs biological process
reactive oxygen species metabolic process Hs biological process
cell-cell adhesion Hs biological process
positive regulation of ceramide biosynthetic process Hs biological process
chondrocyte differentiation Hs biological process
Notch binding Hs molecular function
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
gap junction Hs cellular component
regulation of gene expression Hs biological process
cell junction Hs cellular component
negative regulation of cell growth Hs biological process
axon Hs cellular component
dendrite Hs cellular component
cell adhesion mediated by integrin Hs biological process
endothelial cell chemotaxis Hs biological process
neuronal cell body Hs cellular component
intracellular membrane-bounded organelle Hs cellular component
type B pancreatic cell proliferation Hs biological process
positive regulation of Notch signaling pathway Hs biological process
negative regulation of insulin secretion Hs biological process
smooth muscle cell proliferation Hs biological process
negative regulation of inflammatory response Hs biological process
cell chemotaxis Hs biological process
hematopoietic stem cell homeostasis Hs biological process
extracellular exosome Hs cellular component
bone regeneration Hs biological process

GO (Blast)

20 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 211 3.01e-65
fibronectin binding Hs molecular function 275 2.04e-90
integrin binding Hs molecular function 275 2.04e-90
protein binding Hs molecular function 275 2.04e-90
insulin-like growth factor binding Hs molecular function 275 2.04e-90
extracellular region Hs cellular component 275 2.04e-90
proteinaceous extracellular matrix Hs cellular component 275 2.04e-90
extracellular space Hs cellular component 275 2.04e-90
endoplasmic reticulum lumen Hs cellular component 211 3.01e-65
cis-Golgi network Hs cellular component 275 2.04e-90
cytosol Hs cellular component 275 2.04e-90
plasma membrane Hs cellular component 275 2.04e-90
cell cortex Hs cellular component 275 2.04e-90
protein C-terminus binding Hs molecular function 275 2.04e-90
growth factor activity Hs molecular function 275 2.04e-90
heparin binding Hs molecular function 275 2.04e-90
growth factor binding Hs molecular function 211 3.01e-65
extracellular matrix Hs cellular component 211 3.01e-65
perinuclear region of cytoplasm Hs cellular component 275 2.04e-90
extracellular matrix binding Hs molecular function 211 3.01e-65

GO (InterProScan)

4 results

GO Term Analysis Type e-value
regulation of cell growth Pfam biological process 1.7E-7
protein binding SMART molecular function 1.9E-8
insulin-like growth factor binding Pfam molecular function 1.7E-7
extracellular region Pfam cellular component 1.7E-7

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