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Gene Card

Best human hits

KCNQ1; KCNQ4; KCNQ5

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00014338

Gene Model ID

KH2012:KH.S346.10

Location

KhS346:14115..22913

Transcript Models and Sequences

  KH2012:KH.S346.10.v1.B.SL1-1
KH2012:KH.S346.10.v2.B.SL2-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000005380
NCBI Reference Sequence NM_001160065.1
Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
K_chnl_volt-dep_KCNQ PRINTS Potassium channel, voltage dependent, KCNQ
K_chnl_volt-dep_KCNQ_C Pfam Potassium channel, voltage dependent, KCNQ, C-terminal
VG_K_chnl PRINTS Voltage-gated potassium channel
VG_K_chnl PANTHER Voltage-gated potassium channel
Ion_trans_dom Pfam Ion transport domain

GOSlim

35 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
calmodulin binding Orthology molecular function
cytoplasm Orthology cellular component
lysosome Orthology cellular component
endosome Orthology cellular component
early endosome Orthology cellular component
endoplasmic reticulum Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
ion transport Orthology biological process
sensory perception of sound Orthology biological process
membrane Orthology cellular component
integral component of membrane Orthology cellular component
basolateral plasma membrane Orthology cellular component
cytoplasmic vesicle Orthology cellular component
membrane raft Orthology cellular component
transmembrane transport Orthology biological process
cardiovascular system development Orthology biological process
metal ion transport Orthology biological process
monovalent inorganic cation transport Orthology biological process
anion binding Orthology molecular function
nucleobase-containing compound metabolic process Orthology biological process
regulation of gene expression Orthology biological process
macromolecular complex Orthology cellular component
enzyme binding Orthology molecular function
negative regulation of gene expression Orthology biological process
cellular process Orthology biological process
intracellular organelle part Orthology cellular component
organelle membrane Orthology cellular component
protein kinase binding Orthology molecular function
animal organ development Orthology biological process
signaling Orthology biological process
cell-cell signaling Orthology biological process
cytoplasmic part Blast cellular component
membrane part Blast cellular component

GO (Orthology)

53 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
ion channel activity Hs molecular function
voltage-gated ion channel activity Hs molecular function
voltage-gated potassium channel activity Hs molecular function
delayed rectifier potassium channel activity Hs molecular function
potassium channel activity Hs molecular function
protein binding Hs molecular function
calmodulin binding Hs molecular function
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function
cytoplasm Hs cellular component
lysosome Hs cellular component
endosome Hs cellular component
early endosome Hs cellular component
late endosome Hs cellular component
endoplasmic reticulum Hs cellular component
plasma membrane Hs cellular component
regulation of gene expression by genetic imprinting Hs biological process
ion transport Hs biological process
potassium ion transport Hs biological process
sensory perception of sound Hs biological process
regulation of heart contraction Hs biological process
voltage-gated potassium channel complex Hs cellular component
protein phosphatase 1 binding Hs molecular function
positive regulation of heart rate Hs biological process
outward rectifier potassium channel activity Hs molecular function
membrane Hs cellular component
integral component of membrane Hs cellular component
basolateral plasma membrane Hs cellular component
gene silencing Hs biological process
cytoplasmic vesicle membrane Hs cellular component
cytoplasmic vesicle Hs cellular component
ion transmembrane transport Hs biological process
protein kinase A catalytic subunit binding Hs molecular function
protein kinase A regulatory subunit binding Hs molecular function
ion channel complex Hs cellular component
regulation of ion transmembrane transport Hs biological process
ion channel binding Hs molecular function
membrane raft Hs cellular component
inner ear development Hs biological process
intestinal absorption Hs biological process
transmembrane transport Hs biological process
cardiac muscle contraction Hs biological process
regulation of ventricular cardiac muscle cell membrane repolarization Hs biological process
cardiac conduction Hs biological process
renal absorption Hs biological process
potassium ion transmembrane transport Hs biological process
cardiovascular system development Hs biological process
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Hs molecular function
membrane repolarization Hs biological process
membrane repolarization during cardiac muscle cell action potential Hs biological process
voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Hs molecular function
regulation of heart rate by cardiac conduction Hs biological process
scaffold protein binding Hs molecular function
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization Hs molecular function

GO (Blast)

35 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
ion channel activity Hs molecular function 526 0.0
voltage-gated ion channel activity Hs molecular function 526 0.0
voltage-gated potassium channel activity Hs molecular function 526 0.0
delayed rectifier potassium channel activity Hs molecular function 526 0.0
potassium channel activity Hs molecular function 526 0.0
protein binding Hs molecular function 526 0.0
calmodulin binding Hs molecular function 526 0.0
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function 526 0.0
cytoplasm Hs cellular component 526 0.0
lysosome Hs cellular component 526 0.0
endosome Hs cellular component 526 0.0
early endosome Hs cellular component 526 0.0
late endosome Hs cellular component 526 0.0
endoplasmic reticulum Hs cellular component 526 0.0
plasma membrane Hs cellular component 526 0.0
integral component of plasma membrane Hs cellular component 392 4.08e-126
voltage-gated potassium channel complex Hs cellular component 526 0.0
protein phosphatase 1 binding Hs molecular function 526 0.0
basal plasma membrane Hs cellular component 379 1.13e-123
outward rectifier potassium channel activity Hs molecular function 526 0.0
membrane Hs cellular component 526 0.0
integral component of membrane Hs cellular component 526 0.0
basolateral plasma membrane Hs cellular component 526 0.0
clathrin coat Hs cellular component 392 4.08e-126
cytoplasmic vesicle membrane Hs cellular component 526 0.0
cytoplasmic vesicle Hs cellular component 526 0.0
protein kinase A catalytic subunit binding Hs molecular function 526 0.0
protein kinase A regulatory subunit binding Hs molecular function 526 0.0
ion channel complex Hs cellular component 526 0.0
ion channel binding Hs molecular function 526 0.0
membrane raft Hs cellular component 526 0.0
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Hs molecular function 526 0.0
voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Hs molecular function 526 0.0
scaffold protein binding Hs molecular function 526 0.0
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization Hs molecular function 526 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
ion channel activity Pfam molecular function 1.2E-25
voltage-gated potassium channel activity PANTHER molecular function 6.5E-235
ion transport Pfam biological process 1.2E-25
voltage-gated potassium channel complex PANTHER cellular component 6.5E-235
membrane Pfam cellular component 1.2E-25
transmembrane transport Pfam biological process 1.2E-25

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