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GENE CARD

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Gene Card

Best human hits

IRAK1; IRAK2; IRAK4

Unique Gene ID

Cirobu.g00008824

Gene Model ID

KH2012:KH.C8.21

Location

KhC8:4622026..4626991

External Database Gene Card
Collections

Gateway full ORF

2 results

cien123987

Plate: VES89_L15

cien192931

Plate: VES100_N04

Gene collection 1 (N. Satoh)

1 result

citb040d18

Plate: R1CiGC32h18

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
DEATH-like_dom_sf SUPERFAMILY Death-like domain superfamily
Prot_kinase_dom SMART Protein kinase domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Prot_kinase_dom ProSiteProfiles Protein kinase domain

GOSlim

37 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
magnesium ion binding Orthology molecular function
immune system process Orthology biological process
protein kinase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular space Orthology cellular component
intracellular Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
protein phosphorylation Orthology biological process
signal transduction Orthology biological process
membrane Blast cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
transferase activity Orthology molecular function
cytokine-mediated signaling pathway Orthology biological process
intracellular signal transduction Orthology biological process
protein homodimerization activity Blast molecular function
innate immune response Orthology biological process
protein heterodimerization activity Blast molecular function
receptor binding Orthology molecular function
cellular response to stress Orthology biological process
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
endosome Orthology cellular component
bounding membrane of organelle Orthology cellular component
transcription factor activity, sequence-specific DNA binding Orthology molecular function
positive regulation of signal transduction Orthology biological process
cell migration Orthology biological process
enzyme regulator activity Blast molecular function
intracellular non-membrane-bounded organelle Blast cellular component
integral component of plasma membrane Blast cellular component
macromolecular complex Blast cellular component

GO (Orthology)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
magnesium ion binding Hs molecular function
cytokine production Hs biological process
toll-like receptor signaling pathway Hs biological process
immune system process Hs biological process
neutrophil mediated immunity Hs biological process
MyD88-dependent toll-like receptor signaling pathway Hs biological process
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
interleukin-1 receptor binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
extracellular space Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
protein phosphorylation Hs biological process
signal transduction Hs biological process
JNK cascade Hs biological process
endosome membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
transferase activity Hs molecular function
cytokine-mediated signaling pathway Hs biological process
toll-like receptor 9 signaling pathway Hs biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
innate immune response Hs biological process
positive regulation of NF-kappaB transcription factor activity Hs biological process
interleukin-1-mediated signaling pathway Hs biological process
neutrophil migration Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 205 1.54e-59
magnesium ion binding Hs molecular function 205 1.54e-59
protein kinase activity Hs molecular function 205 1.54e-59
protein serine/threonine kinase activity Hs molecular function 205 1.54e-59
NF-kappaB-inducing kinase activity Hs molecular function 137 5.88e-34
interleukin-1 receptor binding Hs molecular function 205 1.54e-59
protein binding Hs molecular function 205 1.54e-59
ATP binding Hs molecular function 205 1.54e-59
extracellular space Hs cellular component 205 1.54e-59
intracellular Hs cellular component 205 1.54e-59
nucleus Hs cellular component 205 1.54e-59
cytoplasm Hs cellular component 205 1.54e-59
lipid droplet Hs cellular component 137 5.88e-34
cytosol Hs cellular component 205 1.54e-59
plasma membrane Hs cellular component 205 1.54e-59
endosome membrane Hs cellular component 205 1.54e-59
membrane Hs cellular component 137 5.88e-34
kinase activity Hs molecular function 205 1.54e-59
transferase activity Hs molecular function 205 1.54e-59
heat shock protein binding Hs molecular function 137 5.88e-34
protein homodimerization activity Hs molecular function 137 5.88e-34
interleukin-1 receptor complex Hs cellular component 137 5.88e-34
protein heterodimerization activity Hs molecular function 137 5.88e-34

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 1.9E-46
ATP binding SMART molecular function 6.6E-42
protein phosphorylation Pfam biological process 1.9E-46