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Gene Card

Best human hits

PLCB1; PLCB2; PLCB4

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00006467

Gene Model ID

KH2012:KH.C4.381

Location

KhC4:1101166..1128138

Transcript Models and Sequences

  KH2012:KH.C4.381.v1.A.SL1-2
KH2012:KH.C4.381.v2.A.SL1-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000008028
ENSEMBL ENSCING00000018837
ENSEMBL ENSCING00000023564
Collections

Gateway full ORF

2 results

cien72131

Plate: VES81_C15

cien134587

Plate: VES91_K09

Gene collection 1 (N. Satoh)

2 results

ciad041o15

Plate: R1CiGC04f21

ciht035p05

Plate: R1CiGC44g05

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

16 results

IPR Term Analysis Definition
PLC-like_Pdiesterase_TIM-brl Gene3D PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
PI-PLC_fam PRINTS Phosphoinositide phospholipase C family
PLC-beta PIRSF Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
PLC_EF-hand-like Pfam Phosphoinositide-specific phospholipase C, EF-hand-like domain
PLipase_C_Pinositol-sp_Y SMART Phospholipase C, phosphatidylinositol-specific, Y domain
PLipase_C_Pinositol-sp_Y Pfam Phospholipase C, phosphatidylinositol-specific, Y domain
PI-PLC_fam PANTHER Phosphoinositide phospholipase C family
C2_domain_sf Gene3D C2 domain superfamily
PLipase_C_PInositol-sp_X_dom SMART Phosphatidylinositol-specific phospholipase C, X domain
C2_dom SMART C2 domain
PLipase_C_Pinositol-sp_Y ProSiteProfiles Phospholipase C, phosphatidylinositol-specific, Y domain
PLipase_C_PInositol-sp_X_dom Pfam Phosphatidylinositol-specific phospholipase C, X domain
PLipase_C_PInositol-sp_X_dom ProSiteProfiles Phosphatidylinositol-specific phospholipase C, X domain
C2_dom ProSiteProfiles C2 domain
PLC-like_Pdiesterase_TIM-brl SUPERFAMILY PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair

GOSlim

56 results

GO Term Annotation Origin Type
G2/M transition of mitotic cell cycle Orthology biological process
signal transducer activity Orthology molecular function
GTPase activator activity Orthology molecular function
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
calmodulin binding Orthology molecular function
intracellular Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
signal transduction Orthology biological process
G-protein coupled receptor signaling pathway Orthology biological process
brain development Orthology biological process
membrane Orthology cellular component
nuclear speck Orthology cellular component
hydrolase activity Orthology molecular function
enzyme binding Orthology molecular function
nuclear membrane Orthology cellular component
intracellular signal transduction Orthology biological process
protein homodimerization activity Orthology molecular function
myelin sheath Orthology cellular component
positive regulation of GTPase activity Orthology biological process
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
metal ion binding Orthology molecular function
extracellular exosome Orthology cellular component
nucleoplasm Orthology cellular component
macromolecular complex Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
anion binding Orthology molecular function
organic substance metabolic process Orthology biological process
phosphate-containing compound metabolic process Orthology biological process
positive regulation of hydrolase activity Orthology biological process
cellular response to organic substance Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
nervous system process Orthology biological process
regulation of signal transduction Orthology biological process
multicellular organism development Orthology biological process
cell differentiation Orthology biological process
anatomical structure development Orthology biological process
cellular response to stress Orthology biological process
positive regulation of signal transduction Orthology biological process
protein phosphorylation Orthology biological process
developmental process Orthology biological process
sensory perception Orthology biological process
cell cycle Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
sexual reproduction Orthology biological process
G1/S transition of mitotic cell cycle Orthology biological process
cell adhesion molecule binding Orthology molecular function
endoplasmic reticulum Blast cellular component
organelle Blast cellular component
postsynapse Blast cellular component
neuron part Blast cellular component

GO (Orthology)

57 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
G2/M transition of mitotic cell cycle Hs biological process
nuclear chromatin Hs cellular component
phosphatidylinositol phospholipase C activity Hs molecular function
phospholipase C activity Hs molecular function
signal transducer activity Hs molecular function
GTPase activator activity Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
calmodulin binding Hs molecular function
lamin binding Hs molecular function
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
lipid metabolic process Hs biological process
phospholipid metabolic process Hs biological process
signal transduction Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
activation of phospholipase C activity Hs biological process
G-protein coupled acetylcholine receptor signaling pathway Hs biological process
Wnt signaling pathway, calcium modulating pathway Hs biological process
brain development Hs biological process
memory Hs biological process
phosphoric diester hydrolase activity Hs molecular function
regulation of G-protein coupled receptor protein signaling pathway Hs biological process
membrane Hs cellular component
lipid catabolic process Hs biological process
nuclear speck Hs cellular component
hydrolase activity Hs molecular function
enzyme binding Hs molecular function
cerebral cortex development Hs biological process
nuclear membrane Hs cellular component
intracellular signal transduction Hs biological process
positive regulation of embryonic development Hs biological process
protein homodimerization activity Hs molecular function
myelin sheath Hs cellular component
positive regulation of GTPase activity Hs biological process
fat cell differentiation Hs biological process
positive regulation of myoblast differentiation Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of JNK cascade Hs biological process
phosphatidylinositol metabolic process Hs biological process
metal ion binding Hs molecular function
insulin-like growth factor receptor signaling pathway Hs biological process
positive regulation of developmental growth Hs biological process
sensory perception of bitter taste Hs biological process
regulation of cell cycle Hs biological process
extracellular exosome Hs cellular component
interleukin-1-mediated signaling pathway Hs biological process
regulation of fertilization Hs biological process
positive regulation of G1/S transition of mitotic cell cycle Hs biological process
positive regulation of acrosome reaction Hs biological process
nucleoplasm Hs cellular component
macromolecular complex Hs cellular component
cadherin binding Hs molecular function

GO (Blast)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nuclear chromatin Hs cellular component 705 0.0
phosphatidylinositol phospholipase C activity Hs molecular function 705 0.0
phospholipase C activity Hs molecular function 705 0.0
signal transducer activity Hs molecular function 705 0.0
GTPase activator activity Hs molecular function 705 0.0
calcium ion binding Hs molecular function 705 0.0
protein binding Hs molecular function 705 0.0
calmodulin binding Hs molecular function 705 0.0
lamin binding Hs molecular function 705 0.0
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function 705 0.0
intracellular Hs cellular component 642 0.0
nucleus Hs cellular component 705 0.0
cytoplasm Hs cellular component 705 0.0
smooth endoplasmic reticulum Hs cellular component 631 0.0
cytosol Hs cellular component 705 0.0
phosphoric diester hydrolase activity Hs molecular function 705 0.0
postsynaptic density Hs cellular component 631 0.0
membrane Hs cellular component 705 0.0
nuclear speck Hs cellular component 705 0.0
hydrolase activity Hs molecular function 705 0.0
enzyme binding Hs molecular function 705 0.0
dendrite Hs cellular component 631 0.0
nuclear membrane Hs cellular component 705 0.0
protein homodimerization activity Hs molecular function 705 0.0
myelin sheath Hs cellular component 705 0.0
metal ion binding Hs molecular function 642 0.0
extracellular exosome Hs cellular component 705 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
phosphatidylinositol phospholipase C activity PIRSF molecular function 4.1E-153
calcium ion binding PIRSF molecular function 4.1E-153
lipid metabolic process SUPERFAMILY biological process 5.06E-108
signal transduction SMART biological process 2.7E-56
phosphoric diester hydrolase activity SUPERFAMILY molecular function 5.06E-108
intracellular signal transduction PANTHER biological process 1.3E-264

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