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GENE CARD

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Gene Card

Best human hits

USP40; USP47; USP7

Unique Gene ID

Cirobu.g00005003

Gene Model ID

KH2012:KH.C2.775

Location

KhC2:3073392..3100174

Collections

Gateway full ORF

2 results

cien40065

Plate: VES76_G17

cien128035

Plate: VES90_C08

Gene collection 1 (N. Satoh)

1 result

cicl041g23

Plate: R1CiGC12d19

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
USP_dom ProSiteProfiles Ubiquitin specific protease domain
Peptidase_C19_UCH Pfam Peptidase C19, ubiquitin carboxyl-terminal hydrolase
USP_CS ProSitePatterns Ubiquitin specific protease, conserved site

GOSlim

26 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
nucleus Blast cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Blast cellular component
DNA repair Orthology biological process
proteolysis Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
protein C-terminus binding Blast molecular function
transcription factor binding Blast molecular function
peptidase activity Orthology molecular function
nuclear body Blast cellular component
hydrolase activity Orthology molecular function
ubiquitin protein ligase binding Blast molecular function
macromolecular complex Orthology cellular component
negative regulation of apoptotic process Orthology biological process
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of canonical Wnt signaling pathway Orthology biological process
peptidase activity, acting on L-amino acid peptides Orthology molecular function
G2/M transition of mitotic cell cycle Orthology biological process
intracellular part Orthology cellular component
cellular component organization Orthology biological process
endopeptidase activity Orthology molecular function
intracellular signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process
intracellular non-membrane-bounded organelle Blast cellular component

GO (Orthology)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
thiol-dependent ubiquitin-specific protease activity Hs molecular function
protein binding Hs molecular function
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
DNA repair Hs biological process
base-excision repair Hs biological process
proteolysis Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
peptidase activity Hs molecular function
cysteine-type peptidase activity Hs molecular function
negative regulation of G2/M transition of mitotic cell cycle Hs biological process
protein deubiquitination Hs biological process
hydrolase activity Hs molecular function
SCF ubiquitin ligase complex Hs cellular component
positive regulation of cell growth Hs biological process
cellular response to UV Hs biological process
thiol-dependent ubiquitinyl hydrolase activity Hs molecular function
response to drug Hs biological process
negative regulation of apoptotic process Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
WD40-repeat domain binding Hs molecular function
positive regulation of canonical Wnt signaling pathway Hs biological process
ubiquitinyl hydrolase activity Hs molecular function
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
p53 binding Hs molecular function 170 1.76e-42
cysteine-type endopeptidase activity Hs molecular function 170 1.76e-42
thiol-dependent ubiquitin-specific protease activity Hs molecular function 645 0.0
protein binding Hs molecular function 645 0.0
nucleus Hs cellular component 170 1.76e-42
nucleoplasm Hs cellular component 645 0.0
chromosome Hs cellular component 170 1.76e-42
cytoplasm Hs cellular component 645 0.0
cytosol Hs cellular component 170 1.76e-42
protein C-terminus binding Hs molecular function 170 1.76e-42
transcription factor binding Hs molecular function 170 1.76e-42
peptidase activity Hs molecular function 645 0.0
cysteine-type peptidase activity Hs molecular function 645 0.0
nuclear body Hs cellular component 170 1.76e-42
PML body Hs cellular component 170 1.76e-42
hydrolase activity Hs molecular function 645 0.0
SCF ubiquitin ligase complex Hs cellular component 645 0.0
ubiquitin protein ligase binding Hs molecular function 170 1.76e-42
macromolecular complex Hs cellular component 170 1.76e-42
thiol-dependent ubiquitinyl hydrolase activity Hs molecular function 645 0.0
WD40-repeat domain binding Hs molecular function 645 0.0
ubiquitinyl hydrolase activity Hs molecular function 645 0.0
Lys48-specific deubiquitinase activity Hs molecular function 170 1.76e-42

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ubiquitin-dependent protein catabolic process ProSitePatterns biological process
protein deubiquitination Pfam biological process 2.1E-47
thiol-dependent ubiquitinyl hydrolase activity Pfam molecular function 2.1E-47