Gene Card
Best human hits
PKLR; PKM
Unique Gene ID
Cirobu.g00004446
Gene Model ID
KH2012:KH.C2.265
Location
KhC2:62925..68508
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000004140 |
NCBI Reference Sequence | XM_002129510.3 |
cima885818
Plate: VES69_M19
cien153778
Plate: VES94_K02
cieg029p19
Plate: R1CiGC20k20
cigd038h08
Plate: R1CiGC41h03
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Pyr_Knase | TIGRFAM | Pyruvate kinase |
Pyrv_Knase_C_sf | SUPERFAMILY | Pyruvate kinase, C-terminal domain superfamily |
Pyr_Knase | PRINTS | Pyruvate kinase |
Pyr_Knase | CDD | Pyruvate kinase |
Pyrv_Knase_brl | Pfam | Pyruvate kinase, barrel |
Pyr_Knase | PANTHER | Pyruvate kinase |
Pyrv/PenolPyrv_Kinase-like_dom | SUPERFAMILY | Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily |
Pyrv_Knase_AS | ProSitePatterns | Pyruvate kinase, active site |
Pyrv_Knase_C_sf | Gene3D | Pyruvate kinase, C-terminal domain superfamily |
Pyrv_Knase_C | Pfam | Pyruvate kinase, C-terminal |
Pyrv_Knase-like_insert_dom_sf | SUPERFAMILY | Pyruvate kinase-like, insert domain superfamily |
Pyrv_Knase_insert_dom_sf | Gene3D | Pyruvate kinase, insert domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
magnesium ion binding | Orthology | molecular function |
response to hypoxia | Orthology | biological process |
RNA binding | Orthology | molecular function |
catalytic activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
nucleus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
cytosol | Orthology | cellular component |
metabolic process | Orthology | biological process |
response to organic substance | Orthology | biological process |
programmed cell death | Orthology | biological process |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
transferase activity | Orthology | molecular function |
vesicle | Orthology | cellular component |
identical protein binding | Orthology | molecular function |
myelin sheath | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
extracellular vesicle | Orthology | cellular component |
animal organ development | Orthology | biological process |
phosphotransferase activity, alcohol group as acceptor | Orthology | molecular function |
nucleobase-containing compound metabolic process | Orthology | biological process |
oxidation-reduction process | Orthology | biological process |
organelle | Orthology | cellular component |
cell projection | Orthology | cellular component |
plasma membrane region | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
organic substance metabolic process | Orthology | biological process |
phosphate-containing compound metabolic process | Orthology | biological process |
response to stress | Orthology | biological process |
macromolecular complex binding | Orthology | molecular function |
extracellular region part | Orthology | cellular component |
cellular response to organic substance | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
cytoplasmic vesicle | Orthology | cellular component |
endomembrane system | Orthology | cellular component |
intracellular organelle lumen | Orthology | cellular component |
cellular biosynthetic process | Orthology | biological process |
anion binding | Orthology | molecular function |
adenyl ribonucleotide binding | Orthology | molecular function |
cell adhesion molecule binding | Orthology | molecular function |
protein homooligomerization | Orthology | biological process |
binding | Orthology | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
magnesium ion binding | Hs | molecular function |
response to hypoxia | Hs | biological process |
liver development | Hs | biological process |
RNA binding | Hs | molecular function |
catalytic activity | Hs | molecular function |
pyruvate kinase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
extracellular region | Hs | cellular component |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
cytosol | Hs | cellular component |
cilium | Hs | cellular component |
carbohydrate metabolic process | Hs | biological process |
glucose metabolic process | Hs | biological process |
glycolytic process | Hs | biological process |
ATP biosynthetic process | Hs | biological process |
response to nutrient | Hs | biological process |
metabolic process | Hs | biological process |
response to heat | Hs | biological process |
response to gravity | Hs | biological process |
response to glucose | Hs | biological process |
response to organic substance | Hs | biological process |
response to metal ion | Hs | biological process |
response to lithium ion | Hs | biological process |
programmed cell death | Hs | biological process |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
transferase activity | Hs | molecular function |
MHC class II protein complex binding | Hs | molecular function |
potassium ion binding | Hs | molecular function |
extracellular matrix | Hs | cellular component |
animal organ regeneration | Hs | biological process |
vesicle | Hs | cellular component |
response to insulin | Hs | biological process |
cellular response to insulin stimulus | Hs | biological process |
response to ATP | Hs | biological process |
secretory granule lumen | Hs | cellular component |
identical protein binding | Hs | molecular function |
pyruvate biosynthetic process | Hs | biological process |
myelin sheath | Hs | cellular component |
ADP binding | Hs | molecular function |
cadherin binding | Hs | molecular function |
metal ion binding | Hs | molecular function |
protein homotetramerization | Hs | biological process |
response to cAMP | Hs | biological process |
canonical glycolysis | Hs | biological process |
extracellular exosome | Hs | cellular component |
thyroid hormone binding | Hs | molecular function |
pyruvate kinase complex | Hs | cellular component |
extracellular vesicle | Hs | cellular component |
ficolin-1-rich granule lumen | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 754 | 0.0 |
magnesium ion binding | Hs | molecular function | 754 | 0.0 |
RNA binding | Hs | molecular function | 754 | 0.0 |
catalytic activity | Hs | molecular function | 754 | 0.0 |
pyruvate kinase activity | Hs | molecular function | 754 | 0.0 |
protein binding | Hs | molecular function | 754 | 0.0 |
ATP binding | Hs | molecular function | 754 | 0.0 |
extracellular region | Hs | cellular component | 754 | 0.0 |
nucleus | Hs | cellular component | 754 | 0.0 |
cytoplasm | Hs | cellular component | 754 | 0.0 |
mitochondrion | Hs | cellular component | 754 | 0.0 |
cytosol | Hs | cellular component | 754 | 0.0 |
cilium | Hs | cellular component | 754 | 0.0 |
kinase activity | Hs | molecular function | 754 | 0.0 |
transferase activity | Hs | molecular function | 754 | 0.0 |
MHC class II protein complex binding | Hs | molecular function | 754 | 0.0 |
potassium ion binding | Hs | molecular function | 754 | 0.0 |
extracellular matrix | Hs | cellular component | 754 | 0.0 |
vesicle | Hs | cellular component | 754 | 0.0 |
secretory granule lumen | Hs | cellular component | 754 | 0.0 |
identical protein binding | Hs | molecular function | 754 | 0.0 |
myelin sheath | Hs | cellular component | 754 | 0.0 |
ADP binding | Hs | molecular function | 754 | 0.0 |
cadherin binding | Hs | molecular function | 754 | 0.0 |
metal ion binding | Hs | molecular function | 754 | 0.0 |
extracellular exosome | Hs | cellular component | 754 | 0.0 |
thyroid hormone binding | Hs | molecular function | 754 | 0.0 |
pyruvate kinase complex | Hs | cellular component | 754 | 0.0 |
extracellular vesicle | Hs | cellular component | 754 | 0.0 |
ficolin-1-rich granule lumen | Hs | cellular component | 754 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
magnesium ion binding | CDD | molecular function | 0.0 |
catalytic activity | SUPERFAMILY | molecular function | 1.01E-102 |
pyruvate kinase activity | CDD | molecular function | 0.0 |
glycolytic process | CDD | biological process | 0.0 |
potassium ion binding | CDD | molecular function | 0.0 |