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GENE CARD

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Gene Card

Best human hits

PKD1; PKD1L2; PKD1L3

Unique Gene ID

Cirobu.g00001455

Gene Model ID

KH2012:KH.C10.249

Location

KhC10:1735228..1784272

Transcript Models and Sequences

  KH2012:KH.C10.249.v1.A.SL1-1

External Database Gene Card
Collections

Gateway full ORF

2 results

cien67929

Plate: VES80_A20

cien174814

Plate: VES97_K08

Gene collection 1 (N. Satoh)

2 results

cieg061i14

Plate: R1CiGC39n18

cign073d16

Plate: R1CiGC42p08

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

25 results

IPR Term Analysis Definition
PKD_dom ProSiteProfiles PKD domain
Leu-rich_rpt ProSiteProfiles Leucine-rich repeat
PLAT/LH2_dom SMART PLAT/LH2 domain
Ig-like_fold Gene3D Immunoglobulin-like fold
PKD_dom_sf SUPERFAMILY PKD domain superfamily
GPS ProSiteProfiles GPS motif
GPS SMART GPS motif
C-type_lectin-like Pfam C-type lectin-like
PKD_dom Pfam PKD domain
C-type_lectin-like ProSiteProfiles C-type lectin-like
PKD/Chitinase_dom SMART PKD/Chitinase domain
REJ_dom ProSiteProfiles REJ domain
Leu-rich_rpt Pfam Leucine-rich repeat
PKD1_2_channel Pfam Polycystin cation channel, PKD1/PKD2
LRR_dom_sf Gene3D Leucine-rich repeat domain superfamily
CTDL_fold SUPERFAMILY C-type lectin fold
PLAT/LH2_dom Pfam PLAT/LH2 domain
PKD/REJ-like Pfam PKD/REJ-like domain
PLAT/LH2_dom ProSiteProfiles PLAT/LH2 domain
PC1 PRINTS Polycystic kidney disease type 1 protein
Cys-rich_flank_reg_C SMART Cysteine-rich flanking region, C-terminal
PLAT/LH2_dom_sf SUPERFAMILY PLAT/LH2 domain superfamily
Leu-rich_rpt_typical-subtyp SMART Leucine-rich repeat, typical subtype
C-type_lectin-like SMART C-type lectin-like
C-type_lectin-like/link_sf Gene3D C-type lectin-like/link domain superfamily

GOSlim

55 results

GO Term Annotation Origin Type
Golgi membrane Orthology cellular component
blood vessel development Orthology biological process
calcium ion binding Blast molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
cytoplasm Orthology cellular component
Golgi apparatus Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
nitrogen compound metabolic process Orthology biological process
cation transport Blast biological process
heart development Orthology biological process
anatomical structure morphogenesis Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
basolateral plasma membrane Orthology cellular component
protein kinase binding Orthology molecular function
cell projection Orthology cellular component
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
extracellular exosome Orthology cellular component
animal organ development Orthology biological process
macromolecular complex Orthology cellular component
metal ion transport Orthology biological process
transmembrane transport Orthology biological process
organelle Orthology cellular component
plasma membrane region Orthology cellular component
intracellular protein transport Orthology biological process
cell adhesion Orthology biological process
cellular process Orthology biological process
cell Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
plasma membrane part Orthology cellular component
protein phosphorylation Orthology biological process
central nervous system development Orthology biological process
nervous system development Orthology biological process
binding Orthology molecular function
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
cytoplasmic vesicle Orthology cellular component
bounding membrane of organelle Orthology cellular component
response to stress Orthology biological process
vasculature development Orthology biological process
regulation of molecular function Orthology biological process
protein localization Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
system development Orthology biological process
multicellular organism development Orthology biological process
reproductive process Orthology biological process
cell projection membrane Orthology cellular component
microtubule-based process Orthology biological process
regulation of cellular metabolic process Orthology biological process
proteolysis Orthology biological process
sensory perception Blast biological process
transmembrane signaling receptor activity Blast molecular function

GO (Orthology)

60 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
Golgi membrane Hs cellular component
cartilage condensation Hs biological process
blood vessel development Hs biological process
kidney development Hs biological process
liver development Hs biological process
polycystin complex Hs cellular component
calcium channel activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
Golgi apparatus Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
cilium Hs cellular component
protein export from nucleus Hs biological process
nitrogen compound metabolic process Hs biological process
calcium ion transport Hs biological process
cell cycle arrest Hs biological process
homophilic cell adhesion via plasma membrane adhesion molecules Hs biological process
cell-matrix adhesion Hs biological process
positive regulation of cytosolic calcium ion concentration Hs biological process
JAK-STAT cascade Hs biological process
heart development Hs biological process
anatomical structure morphogenesis Hs biological process
cell surface Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
basolateral plasma membrane Hs cellular component
lateral plasma membrane Hs cellular component
peptidyl-serine phosphorylation Hs biological process
protein kinase binding Hs molecular function
protein domain specific binding Hs molecular function
spinal cord development Hs biological process
neural tube development Hs biological process
establishment of cell polarity Hs biological process
regulation of cell adhesion Hs biological process
carbohydrate binding Hs molecular function
Golgi-associated vesicle membrane Hs cellular component
motile cilium Hs cellular component
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle Hs biological process
positive regulation of protein binding Hs biological process
response to fluid shear stress Hs biological process
lymph vessel morphogenesis Hs biological process
cytoplasmic sequestering of transcription factor Hs biological process
cell projection Hs cellular component
skin development Hs biological process
ion channel binding Hs molecular function
positive regulation of transcription from RNA polymerase II promoter Hs biological process
digestive tract development Hs biological process
branching morphogenesis of an epithelial tube Hs biological process
genitalia development Hs biological process
detection of mechanical stimulus Hs biological process
cartilage development Hs biological process
ciliary membrane Hs cellular component
regulation of mitotic spindle organization Hs biological process
regulation of proteasomal protein catabolic process Hs biological process
extracellular exosome Hs cellular component
calcium ion transmembrane transport Hs biological process
renal system development Hs biological process
cell-cell adhesion Hs biological process

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
Golgi membrane Hs cellular component 1065 0.0
polycystin complex Hs cellular component 1065 0.0
cation channel activity Hs molecular function 189 2.25e-47
calcium channel activity Hs molecular function 1065 0.0
calcium ion binding Hs molecular function 211 7.43e-54
protein binding Hs molecular function 1065 0.0
nucleus Hs cellular component 1065 0.0
cytoplasm Hs cellular component 1065 0.0
Golgi apparatus Hs cellular component 1065 0.0
plasma membrane Hs cellular component 1065 0.0
integral component of plasma membrane Hs cellular component 1065 0.0
cilium Hs cellular component 1065 0.0
cation transmembrane transporter activity Hs molecular function 189 2.25e-47
cell surface Hs cellular component 1065 0.0
membrane Hs cellular component 1065 0.0
integral component of membrane Hs cellular component 1065 0.0
basolateral plasma membrane Hs cellular component 1065 0.0
lateral plasma membrane Hs cellular component 1065 0.0
protein kinase binding Hs molecular function 1065 0.0
protein domain specific binding Hs molecular function 1065 0.0
carbohydrate binding Hs molecular function 1065 0.0
Golgi-associated vesicle membrane Hs cellular component 1065 0.0
motile cilium Hs cellular component 1065 0.0
sour taste receptor activity Hs molecular function 189 2.25e-47
cation channel complex Hs cellular component 189 2.25e-47
cell projection Hs cellular component 1065 0.0
receptor complex Hs cellular component 189 2.25e-47
ion channel binding Hs molecular function 1065 0.0
ciliary membrane Hs cellular component 1065 0.0
extracellular exosome Hs cellular component 1065 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
kidney development PRINTS biological process 6.0E-14
protein binding SUPERFAMILY molecular function 1.3E-26
integral component of membrane PRINTS cellular component 6.0E-14