Gene Card
Best human hits
ANKFY1; HGS; TOM1
Species
Unique Gene ID
Harore.g00013916
Gene Model ID
Harore.CG.MTP2014.S76.g13916
Location
S76:159919..167851
Transcript Models and Sequences
Harore.CG.MTP2014.S76.g13916.01.t
Harore.CG.MTP2014.S76.g13916.02.t
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
HRS_helical | Pfam | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain |
ENTH_VHS | Gene3D | ENTH/VHS |
VHS_dom | SMART | VHS domain |
Znf_FYVE | SMART | FYVE zinc finger |
Znf_FYVE_PHD | SUPERFAMILY | Zinc finger, FYVE/PHD-type |
VHS_dom | ProSiteProfiles | VHS domain |
UIM_dom | ProSiteProfiles | Ubiquitin interacting motif |
ENTH_VHS | SUPERFAMILY | ENTH/VHS |
VHS_dom | Pfam | VHS domain |
Znf_FYVE-rel | ProSiteProfiles | Zinc finger, FYVE-related |
Znf_FYVE | Pfam | FYVE zinc finger |
Ubi-bd_Hrs_VPS27 | PIRSF | Ubiquitin binding protein, Hrs/VPS27 |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Orthology | molecular function |
intracellular | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
lysosome | Orthology | cellular component |
lysosomal membrane | Blast | cellular component |
endosome | Orthology | cellular component |
early endosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Blast | cellular component |
intracellular protein transport | Orthology | biological process |
signal transduction | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
protein transport | Orthology | biological process |
membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
intracellular membrane-bounded organelle | Orthology | cellular component |
ubiquitin-like protein ligase binding | Orthology | molecular function |
metal ion binding | Orthology | molecular function |
membrane organization | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
protein localization to membrane | Orthology | biological process |
protein targeting | Orthology | biological process |
establishment of protein localization to organelle | Orthology | biological process |
intracellular transport | Orthology | biological process |
angiogenesis | Orthology | biological process |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
cell surface receptor signaling pathway | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
whole membrane | Orthology | cellular component |
intracellular organelle part | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
protein metabolic process | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
regulation of catalytic activity | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
protein serine/threonine kinase activity | Orthology | molecular function |
regulation of signal transduction | Orthology | biological process |
enzyme binding | Blast | molecular function |
membrane part | Blast | cellular component |
endomembrane system | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
anion binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
protein binding | Hs | molecular function |
intracellular | Hs | cellular component |
cytoplasm | Hs | cellular component |
lysosome | Hs | cellular component |
endosome | Hs | cellular component |
early endosome | Hs | cellular component |
cytosol | Hs | cellular component |
protein targeting to lysosome | Hs | biological process |
intracellular protein transport | Hs | biological process |
signal transduction | Hs | biological process |
negative regulation of cell proliferation | Hs | biological process |
positive regulation of gene expression | Hs | biological process |
protein transport | Hs | biological process |
membrane | Hs | cellular component |
endosomal transport | Hs | biological process |
macroautophagy | Hs | biological process |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
negative regulation of angiogenesis | Hs | biological process |
protein deubiquitination | Hs | biological process |
protein domain specific binding | Hs | molecular function |
negative regulation of vascular endothelial growth factor receptor signaling pathway | Hs | biological process |
early endosome membrane | Hs | cellular component |
multivesicular body membrane | Hs | cellular component |
ESCRT-0 complex | Hs | cellular component |
multivesicular body assembly | Hs | biological process |
negative regulation of epidermal growth factor receptor signaling pathway | Hs | biological process |
regulation of protein catabolic process | Hs | biological process |
intracellular membrane-bounded organelle | Hs | cellular component |
regulation of MAP kinase activity | Hs | biological process |
ubiquitin-like protein ligase binding | Hs | molecular function |
negative regulation of JAK-STAT cascade | Hs | biological process |
metal ion binding | Hs | molecular function |
membrane organization | Hs | biological process |
extracellular exosome | Hs | cellular component |
protein localization to membrane | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
protein binding | Hs | molecular function | 563 | 0.0 |
intracellular | Hs | cellular component | 563 | 0.0 |
cytoplasm | Hs | cellular component | 563 | 0.0 |
lysosome | Hs | cellular component | 563 | 0.0 |
lysosomal membrane | Hs | cellular component | 82.4 | 5.01e-16 |
endosome | Hs | cellular component | 563 | 0.0 |
early endosome | Hs | cellular component | 563 | 0.0 |
cytosol | Hs | cellular component | 563 | 0.0 |
plasma membrane | Hs | cellular component | 78.2 | 5.13e-15 |
endosome membrane | Hs | cellular component | 82.4 | 5.01e-16 |
membrane | Hs | cellular component | 563 | 0.0 |
kinase activity | Hs | molecular function | 563 | 0.0 |
Rab GTPase binding | Hs | molecular function | 82.4 | 5.01e-16 |
protein domain specific binding | Hs | molecular function | 563 | 0.0 |
clathrin binding | Hs | molecular function | 78.2 | 5.13e-15 |
retromer complex | Hs | cellular component | 82.4 | 5.01e-16 |
early endosome membrane | Hs | cellular component | 563 | 0.0 |
multivesicular body membrane | Hs | cellular component | 563 | 0.0 |
ESCRT-0 complex | Hs | cellular component | 563 | 0.0 |
azurophil granule membrane | Hs | cellular component | 78.2 | 5.13e-15 |
specific granule membrane | Hs | cellular component | 78.2 | 5.13e-15 |
intracellular membrane-bounded organelle | Hs | cellular component | 563 | 0.0 |
macropinosome | Hs | cellular component | 82.4 | 5.01e-16 |
ubiquitin-like protein ligase binding | Hs | molecular function | 563 | 0.0 |
metal ion binding | Hs | molecular function | 563 | 0.0 |
extracellular exosome | Hs | cellular component | 563 | 0.0 |
phosphatidylinositol phosphate binding | Hs | molecular function | 82.4 | 5.01e-16 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
intracellular protein transport | Pfam | biological process | 3.5E-33 |
metal ion binding | SMART | molecular function | 4.6E-29 |