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GENE CARD

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Gene Card

Best human hits

ANKFY1; HGS; TOM1

Species

H.roretzi

Unique Gene ID

Harore.g00013916

Gene Model ID

Harore.CG.MTP2014.S76.g13916

Location

S76:159919..167851

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
Znf_RING/FYVE/PHD Gene3D Zinc finger, RING/FYVE/PHD-type
HRS_helical Pfam Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain
ENTH_VHS Gene3D ENTH/VHS
VHS_dom SMART VHS domain
Znf_FYVE SMART FYVE zinc finger
Znf_FYVE_PHD SUPERFAMILY Zinc finger, FYVE/PHD-type
VHS_dom ProSiteProfiles VHS domain
UIM_dom ProSiteProfiles Ubiquitin interacting motif
ENTH_VHS SUPERFAMILY ENTH/VHS
VHS_dom Pfam VHS domain
Znf_FYVE-rel ProSiteProfiles Zinc finger, FYVE-related
Znf_FYVE Pfam FYVE zinc finger
Ubi-bd_Hrs_VPS27 PIRSF Ubiquitin binding protein, Hrs/VPS27

GOSlim

46 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
intracellular Orthology cellular component
cytoplasm Orthology cellular component
lysosome Orthology cellular component
lysosomal membrane Blast cellular component
endosome Orthology cellular component
early endosome Orthology cellular component
cytosol Orthology cellular component
plasma membrane Blast cellular component
intracellular protein transport Orthology biological process
signal transduction Orthology biological process
negative regulation of cell proliferation Orthology biological process
positive regulation of gene expression Orthology biological process
protein transport Orthology biological process
membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
intracellular membrane-bounded organelle Orthology cellular component
ubiquitin-like protein ligase binding Orthology molecular function
metal ion binding Orthology molecular function
membrane organization Orthology biological process
extracellular exosome Orthology cellular component
protein localization to membrane Orthology biological process
protein targeting Orthology biological process
establishment of protein localization to organelle Orthology biological process
intracellular transport Orthology biological process
angiogenesis Orthology biological process
peptidase activity, acting on L-amino acid peptides Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
negative regulation of signal transduction Orthology biological process
cellular response to organic substance Orthology biological process
whole membrane Orthology cellular component
intracellular organelle part Orthology cellular component
bounding membrane of organelle Orthology cellular component
macromolecular complex Orthology cellular component
protein metabolic process Orthology biological process
regulation of cellular metabolic process Orthology biological process
regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
regulation of signal transduction Orthology biological process
enzyme binding Blast molecular function
membrane part Blast cellular component
endomembrane system Blast cellular component
cytoplasmic vesicle Blast cellular component
anion binding Blast molecular function

GO (Orthology)

36 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
protein binding Hs molecular function
intracellular Hs cellular component
cytoplasm Hs cellular component
lysosome Hs cellular component
endosome Hs cellular component
early endosome Hs cellular component
cytosol Hs cellular component
protein targeting to lysosome Hs biological process
intracellular protein transport Hs biological process
signal transduction Hs biological process
negative regulation of cell proliferation Hs biological process
positive regulation of gene expression Hs biological process
protein transport Hs biological process
membrane Hs cellular component
endosomal transport Hs biological process
macroautophagy Hs biological process
kinase activity Hs molecular function
phosphorylation Hs biological process
negative regulation of angiogenesis Hs biological process
protein deubiquitination Hs biological process
protein domain specific binding Hs molecular function
negative regulation of vascular endothelial growth factor receptor signaling pathway Hs biological process
early endosome membrane Hs cellular component
multivesicular body membrane Hs cellular component
ESCRT-0 complex Hs cellular component
multivesicular body assembly Hs biological process
negative regulation of epidermal growth factor receptor signaling pathway Hs biological process
regulation of protein catabolic process Hs biological process
intracellular membrane-bounded organelle Hs cellular component
regulation of MAP kinase activity Hs biological process
ubiquitin-like protein ligase binding Hs molecular function
negative regulation of JAK-STAT cascade Hs biological process
metal ion binding Hs molecular function
membrane organization Hs biological process
extracellular exosome Hs cellular component
protein localization to membrane Hs biological process

GO (Blast)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
protein binding Hs molecular function 563 0.0
intracellular Hs cellular component 563 0.0
cytoplasm Hs cellular component 563 0.0
lysosome Hs cellular component 563 0.0
lysosomal membrane Hs cellular component 82.4 5.01e-16
endosome Hs cellular component 563 0.0
early endosome Hs cellular component 563 0.0
cytosol Hs cellular component 563 0.0
plasma membrane Hs cellular component 78.2 5.13e-15
endosome membrane Hs cellular component 82.4 5.01e-16
membrane Hs cellular component 563 0.0
kinase activity Hs molecular function 563 0.0
Rab GTPase binding Hs molecular function 82.4 5.01e-16
protein domain specific binding Hs molecular function 563 0.0
clathrin binding Hs molecular function 78.2 5.13e-15
retromer complex Hs cellular component 82.4 5.01e-16
early endosome membrane Hs cellular component 563 0.0
multivesicular body membrane Hs cellular component 563 0.0
ESCRT-0 complex Hs cellular component 563 0.0
azurophil granule membrane Hs cellular component 78.2 5.13e-15
specific granule membrane Hs cellular component 78.2 5.13e-15
intracellular membrane-bounded organelle Hs cellular component 563 0.0
macropinosome Hs cellular component 82.4 5.01e-16
ubiquitin-like protein ligase binding Hs molecular function 563 0.0
metal ion binding Hs molecular function 563 0.0
extracellular exosome Hs cellular component 563 0.0
phosphatidylinositol phosphate binding Hs molecular function 82.4 5.01e-16

GO (InterProScan)

2 results

GO Term Analysis Type e-value
intracellular protein transport Pfam biological process 3.5E-33
metal ion binding SMART molecular function 4.6E-29