Gene Card
Best human hits
ACVR2A; ACVR2B; BMPR2
Species
Unique Gene ID
Harore.g00004344
Gene Model ID
Harore.CG.MTP2014.S7.g04344
Location
S7:283887..288028
Transcript Models and Sequences
Harore.CG.MTP2014.S7.g04344.01.t
Harore.CG.MTP2014.S7.g04344.02.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
6 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| Prot_kinase_dom | Pfam | Protein kinase domain |
| TGFB_receptor | PANTHER | Ser/Thr protein kinase, TGFB receptor |
| Activin_recp | Pfam | Activin types I and II receptor domain |
| Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
GOSlim
34 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| nucleotide binding | Blast | molecular function |
| protein kinase activity | Blast | molecular function |
| protein serine/threonine kinase activity | Blast | molecular function |
| protein binding | Blast | molecular function |
| ATP binding | Blast | molecular function |
| extracellular space | Blast | cellular component |
| nucleoplasm | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| integral component of plasma membrane | Blast | cellular component |
| protein phosphorylation | InterProScan | biological process |
| cell surface | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| kinase activity | Blast | molecular function |
| apical plasma membrane | Blast | cellular component |
| transferase activity | Blast | molecular function |
| macromolecular complex | Blast | cellular component |
| neuronal cell body | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| cell surface receptor signaling pathway | Blast | biological process |
| transmembrane signaling receptor activity | Blast | molecular function |
| membrane raft | Blast | cellular component |
| plasma membrane region | Blast | cellular component |
| adherens junction | Blast | cellular component |
| basolateral plasma membrane | Blast | cellular component |
| organelle | Blast | cellular component |
| postsynapse | Blast | cellular component |
| neuron part | Blast | cellular component |
| signaling receptor activity | Blast | molecular function |
| macromolecular complex binding | Blast | molecular function |
| plasma membrane part | Blast | cellular component |
| regulation of transcription from RNA polymerase II promoter | Blast | biological process |
| cellular response to organic substance | Blast | biological process |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
41 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 179 | 8.43e-48 |
| protein kinase activity | Hs | molecular function | 179 | 8.43e-48 |
| protein serine/threonine kinase activity | Hs | molecular function | 179 | 8.43e-48 |
| transmembrane receptor protein serine/threonine kinase activity | Hs | molecular function | 179 | 8.43e-48 |
| signal transducer, downstream of receptor, with serine/threonine kinase activity | Hs | molecular function | 179 | 8.43e-48 |
| protein serine/threonine/tyrosine kinase activity | Hs | molecular function | 109 | 3.60e-25 |
| receptor activity | Hs | molecular function | 179 | 8.43e-48 |
| protein binding | Hs | molecular function | 179 | 8.43e-48 |
| ATP binding | Hs | molecular function | 179 | 8.43e-48 |
| extracellular space | Hs | cellular component | 179 | 8.43e-48 |
| nucleoplasm | Hs | cellular component | 179 | 8.43e-48 |
| cytoplasm | Hs | cellular component | 179 | 8.43e-48 |
| plasma membrane | Hs | cellular component | 179 | 8.43e-48 |
| integral component of plasma membrane | Hs | cellular component | 179 | 8.43e-48 |
| caveola | Hs | cellular component | 179 | 8.43e-48 |
| cell-cell adherens junction | Hs | cellular component | 179 | 8.43e-48 |
| basal plasma membrane | Hs | cellular component | 179 | 8.43e-48 |
| cell surface | Hs | cellular component | 179 | 8.43e-48 |
| postsynaptic density | Hs | cellular component | 179 | 8.43e-48 |
| coreceptor activity | Hs | molecular function | 108 | 5.12e-25 |
| membrane | Hs | cellular component | 179 | 8.43e-48 |
| integral component of membrane | Hs | cellular component | 179 | 8.43e-48 |
| kinase activity | Hs | molecular function | 179 | 8.43e-48 |
| apical plasma membrane | Hs | cellular component | 179 | 8.43e-48 |
| activin receptor activity, type II | Hs | molecular function | 179 | 8.43e-48 |
| transferase activity | Hs | molecular function | 179 | 8.43e-48 |
| activin-activated receptor activity | Hs | molecular function | 108 | 5.12e-25 |
| growth factor binding | Hs | molecular function | 179 | 8.43e-48 |
| PDZ domain binding | Hs | molecular function | 108 | 5.12e-25 |
| dendrite | Hs | cellular component | 179 | 8.43e-48 |
| macromolecular complex | Hs | cellular component | 109 | 3.60e-25 |
| inhibin-betaglycan-ActRII complex | Hs | cellular component | 108 | 5.12e-25 |
| inhibin binding | Hs | molecular function | 108 | 5.12e-25 |
| BMP binding | Hs | molecular function | 179 | 8.43e-48 |
| neuronal cell body | Hs | cellular component | 179 | 8.43e-48 |
| receptor complex | Hs | cellular component | 179 | 8.43e-48 |
| protein self-association | Hs | molecular function | 108 | 5.12e-25 |
| spanning component of plasma membrane | Hs | cellular component | 179 | 8.43e-48 |
| metal ion binding | Hs | molecular function | 179 | 8.43e-48 |
| activin binding | Hs | molecular function | 109 | 3.60e-25 |
| BMP receptor activity | Hs | molecular function | 179 | 8.43e-48 |
GO (InterProScan)
7 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | Pfam | molecular function | 3.1E-27 |
| transmembrane receptor protein serine/threonine kinase activity | Pfam | molecular function | 2.4E-6 |
| signal transducer, downstream of receptor, with serine/threonine kinase activity | PANTHER | molecular function | 1.0E-63 |
| ATP binding | PANTHER | molecular function | 1.0E-63 |
| protein phosphorylation | Pfam | biological process | 3.1E-27 |
| transmembrane receptor protein serine/threonine kinase signaling pathway | PANTHER | biological process | 1.0E-63 |
| membrane | PANTHER | cellular component | 1.0E-63 |
