Gene Card
Best human hits
WDR45; WDR45B; WIPI1
Species
Unique Gene ID
Harore.g00005598
Gene Model ID
Harore.CG.MTP2014.S599.g05598
Location
S599:26588..27617
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
5 results
| IPR Term | Analysis | Definition |
|---|---|---|
| WD40_repeat | Pfam | WD40 repeat |
| WD40/YVTN_repeat-like_dom_sf | Gene3D | WD40/YVTN repeat-like-containing domain superfamily |
| WD40_repeat | SMART | WD40 repeat |
| WD40_repeat_dom_sf | SUPERFAMILY | WD40-repeat-containing domain superfamily |
| WIPI4 | PANTHER | WD repeat domain phosphoinositide-interacting protein 4 |
GOSlim
41 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| Golgi membrane | Blast | cellular component |
| receptor binding | Blast | molecular function |
| protein binding | Orthology | molecular function |
| cytoplasm | Orthology | cellular component |
| endosome | Orthology | cellular component |
| Golgi apparatus | Blast | cellular component |
| cytosol | Orthology | cellular component |
| cytoskeleton | Orthology | cellular component |
| membrane | Orthology | cellular component |
| integral component of membrane | Orthology | cellular component |
| cytoplasmic vesicle | Blast | cellular component |
| endoplasmic reticulum | Orthology | cellular component |
| endoplasmic reticulum membrane | Orthology | cellular component |
| plasma membrane | Orthology | cellular component |
| protein transport | Orthology | biological process |
| positive regulation of apoptotic process | Orthology | biological process |
| extracellular exosome | Orthology | cellular component |
| organelle organization | Orthology | biological process |
| cellular protein modification process | Orthology | biological process |
| intracellular organelle part | Orthology | cellular component |
| whole membrane | Orthology | cellular component |
| bounding membrane of organelle | Orthology | cellular component |
| membrane part | Orthology | cellular component |
| anion binding | Orthology | molecular function |
| cytoplasmic part | Orthology | cellular component |
| ubiquitin-like protein transferase activity | Orthology | molecular function |
| ligase activity | Orthology | molecular function |
| cellular protein localization | Orthology | biological process |
| peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
| organic substance transport | Orthology | biological process |
| ion transport | Orthology | biological process |
| transmembrane transport | Orthology | biological process |
| intracellular signal transduction | Orthology | biological process |
| cellular response to stress | Orthology | biological process |
| positive regulation of signal transduction | Orthology | biological process |
| protein phosphorylation | Orthology | biological process |
| endopeptidase activity | Orthology | molecular function |
| positive regulation of hydrolase activity | Orthology | biological process |
| vacuolar membrane | Blast | cellular component |
| Golgi apparatus part | Blast | cellular component |
| transcription factor binding | Blast | molecular function |
GO (Orthology)
26 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| autophagy of mitochondrion | Hs | biological process |
| protein binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| endosome | Hs | cellular component |
| cytosol | Hs | cellular component |
| cytoskeleton | Hs | cellular component |
| protein lipidation | Hs | biological process |
| autophagy | Hs | biological process |
| endosome membrane | Hs | cellular component |
| membrane | Hs | cellular component |
| integral component of membrane | Hs | cellular component |
| extrinsic component of membrane | Hs | cellular component |
| phosphatidylinositol-3-phosphate binding | Hs | molecular function |
| pre-autophagosomal structure membrane | Hs | cellular component |
| protein localization to pre-autophagosomal structure | Hs | biological process |
| autophagy of nucleus | Hs | biological process |
| phosphatidylinositol-3,5-bisphosphate binding | Hs | molecular function |
| endoplasmic reticulum | Hs | cellular component |
| endoplasmic reticulum membrane | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| protein transport | Hs | biological process |
| L-glutamate transport | Hs | biological process |
| positive regulation of stress-activated MAPK cascade | Hs | biological process |
| positive regulation of apoptotic process | Hs | biological process |
| positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | Hs | biological process |
| extracellular exosome | Hs | cellular component |
GO (Blast)
22 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 116 | 3.92e-29 |
| pre-autophagosomal structure | Hs | cellular component | 116 | 3.92e-29 |
| autophagosome membrane | Hs | cellular component | 116 | 3.92e-29 |
| receptor binding | Hs | molecular function | 116 | 3.92e-29 |
| protein binding | Hs | molecular function | 453 | 1.19e-160 |
| cytoplasm | Hs | cellular component | 116 | 3.92e-29 |
| endosome | Hs | cellular component | 116 | 3.92e-29 |
| Golgi apparatus | Hs | cellular component | 116 | 3.92e-29 |
| trans-Golgi network | Hs | cellular component | 116 | 3.92e-29 |
| cytosol | Hs | cellular component | 453 | 1.19e-160 |
| cytoskeleton | Hs | cellular component | 116 | 3.92e-29 |
| endosome membrane | Hs | cellular component | 116 | 3.92e-29 |
| membrane | Hs | cellular component | 453 | 1.19e-160 |
| integral component of membrane | Hs | cellular component | 453 | 1.19e-160 |
| extrinsic component of membrane | Hs | cellular component | 453 | 1.19e-160 |
| clathrin-coated vesicle | Hs | cellular component | 116 | 3.92e-29 |
| estrogen receptor binding | Hs | molecular function | 116 | 3.92e-29 |
| cytoplasmic vesicle | Hs | cellular component | 116 | 3.92e-29 |
| phosphatidylinositol-3-phosphate binding | Hs | molecular function | 453 | 1.19e-160 |
| pre-autophagosomal structure membrane | Hs | cellular component | 453 | 1.19e-160 |
| androgen receptor binding | Hs | molecular function | 116 | 3.92e-29 |
| phosphatidylinositol-3,5-bisphosphate binding | Hs | molecular function | 453 | 1.19e-160 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | SUPERFAMILY | molecular function | 4.43E-32 |
| autophagy | PANTHER | biological process | 4.5E-150 |
