Gene Card
Best human hits
AGAP1; AGAP2; AGAP3
Species
Unique Gene ID
Harore.g00000367
Gene Model ID
Harore.CG.MTP2014.S495.g00367
Location
S495:19113..44569
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
ArfGAP_dom | ProSiteProfiles | Arf GTPase activating protein |
PH_domain | ProSiteProfiles | Pleckstrin homology domain |
PH_domain | Pfam | Pleckstrin homology domain |
Ankyrin_rpt | ProSiteProfiles | Ankyrin repeat |
ARFGAP/RecO | SUPERFAMILY | ARFGAP/RecO-like zinc finger |
Ankyrin_rpt | SMART | Ankyrin repeat |
ArfGAP_dom_sf | Gene3D | ArfGAP domain superfamily |
Ankyrin_rpt-contain_dom | Pfam | Ankyrin repeat-containing domain |
Small_GTPase | Pfam | Small GTPase superfamily |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
Ankyrin_rpt-contain_sf | SUPERFAMILY | Ankyrin repeat-containing domain superfamily |
Ankyrin_rpt-contain_dom | CDD | Ankyrin repeat-containing domain |
ArfGAP_dom | SMART | Arf GTPase activating protein |
ArfGAP_dom | Pfam | Arf GTPase activating protein |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
ArfGAP_dom | PRINTS | Arf GTPase activating protein |
PH_domain | SMART | Pleckstrin homology domain |
Ankyrin_rpt-contain_sf | Gene3D | Ankyrin repeat-containing domain superfamily |
Ankyrin_rpt-contain_dom | ProSiteProfiles | Ankyrin repeat-containing domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
GTPase activity | Orthology | molecular function |
GTPase activator activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
GTP binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleolus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
signal transduction | Orthology | biological process |
protein transport | Orthology | biological process |
membrane | Orthology | cellular component |
protein kinase binding | Orthology | molecular function |
negative regulation of apoptotic process | Orthology | biological process |
positive regulation of GTPase activity | Orthology | biological process |
positive regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
metal ion binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
anion binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
enzyme activator activity | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
positive regulation of catalytic activity | Orthology | biological process |
protein metabolic process | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
GTPase activity | Hs | molecular function |
GTPase activator activity | Hs | molecular function |
protein binding | Hs | molecular function |
GTP binding | Hs | molecular function |
phospholipid binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleolus | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
signal transduction | Hs | biological process |
positive regulation of phosphatidylinositol 3-kinase signaling | Hs | biological process |
protein transport | Hs | biological process |
membrane | Hs | cellular component |
protein kinase binding | Hs | molecular function |
protein kinase activator activity | Hs | molecular function |
activation of protein kinase activity | Hs | biological process |
negative regulation of protein catabolic process | Hs | biological process |
negative regulation of apoptotic process | Hs | biological process |
negative regulation of neuron apoptotic process | Hs | biological process |
positive regulation of GTPase activity | Hs | biological process |
positive regulation of transcription from RNA polymerase II promoter | Hs | biological process |
positive regulation of JAK-STAT cascade | Hs | biological process |
metal ion binding | Hs | molecular function |
extracellular exosome | Hs | cellular component |
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 477 | 2.54e-156 |
GTPase activity | Hs | molecular function | 477 | 2.54e-156 |
GTPase activator activity | Hs | molecular function | 477 | 2.54e-156 |
protein binding | Hs | molecular function | 477 | 2.54e-156 |
GTP binding | Hs | molecular function | 477 | 2.54e-156 |
phospholipid binding | Hs | molecular function | 407 | 5.14e-128 |
nucleus | Hs | cellular component | 305 | 9.66e-90 |
nucleolus | Hs | cellular component | 305 | 9.66e-90 |
cytoplasm | Hs | cellular component | 477 | 2.54e-156 |
mitochondrion | Hs | cellular component | 305 | 9.66e-90 |
membrane | Hs | cellular component | 477 | 2.54e-156 |
protein kinase binding | Hs | molecular function | 305 | 9.66e-90 |
protein kinase activator activity | Hs | molecular function | 305 | 9.66e-90 |
metal ion binding | Hs | molecular function | 477 | 2.54e-156 |
extracellular exosome | Hs | cellular component | 305 | 9.66e-90 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
GTPase activity | Pfam | molecular function | 4.9E-15 |
GTPase activator activity | SMART | molecular function | 2.4E-38 |
protein binding | SMART | molecular function | 0.77 |
GTP binding | Pfam | molecular function | 4.9E-15 |