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GENE CARD

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Gene Card

Best human hits

AGAP1; AGAP2; AGAP3

Species

H.roretzi

Unique Gene ID

Harore.g00000367

Gene Model ID

Harore.CG.MTP2014.S495.g00367

Location

S495:19113..44569

Transcript Models and Sequences

  Harore.CG.MTP2014.S495.g00367.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

19 results

IPR Term Analysis Definition
ArfGAP_dom ProSiteProfiles Arf GTPase activating protein
PH_domain ProSiteProfiles Pleckstrin homology domain
PH_domain Pfam Pleckstrin homology domain
Ankyrin_rpt ProSiteProfiles Ankyrin repeat
ARFGAP/RecO SUPERFAMILY ARFGAP/RecO-like zinc finger
Ankyrin_rpt SMART Ankyrin repeat
ArfGAP_dom_sf Gene3D ArfGAP domain superfamily
Ankyrin_rpt-contain_dom Pfam Ankyrin repeat-containing domain
Small_GTPase Pfam Small GTPase superfamily
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
Ankyrin_rpt-contain_sf SUPERFAMILY Ankyrin repeat-containing domain superfamily
Ankyrin_rpt-contain_dom CDD Ankyrin repeat-containing domain
ArfGAP_dom SMART Arf GTPase activating protein
ArfGAP_dom Pfam Arf GTPase activating protein
PH-like_dom_sf Gene3D PH-like domain superfamily
ArfGAP_dom PRINTS Arf GTPase activating protein
PH_domain SMART Pleckstrin homology domain
Ankyrin_rpt-contain_sf Gene3D Ankyrin repeat-containing domain superfamily
Ankyrin_rpt-contain_dom ProSiteProfiles Ankyrin repeat-containing domain

GOSlim

27 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
GTPase activity Orthology molecular function
GTPase activator activity Orthology molecular function
protein binding Orthology molecular function
GTP binding Orthology molecular function
nucleus Orthology cellular component
nucleolus Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
signal transduction Orthology biological process
protein transport Orthology biological process
membrane Orthology cellular component
protein kinase binding Orthology molecular function
negative regulation of apoptotic process Orthology biological process
positive regulation of GTPase activity Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
extracellular exosome Orthology cellular component
anion binding Orthology molecular function
intracellular signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
enzyme activator activity Orthology molecular function
protein kinase activity Orthology molecular function
positive regulation of catalytic activity Orthology biological process
protein metabolic process Orthology biological process
cell surface receptor signaling pathway Orthology biological process
negative regulation of signal transduction Orthology biological process

GO (Orthology)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
GTPase activity Hs molecular function
GTPase activator activity Hs molecular function
protein binding Hs molecular function
GTP binding Hs molecular function
phospholipid binding Hs molecular function
nucleus Hs cellular component
nucleolus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
signal transduction Hs biological process
positive regulation of phosphatidylinositol 3-kinase signaling Hs biological process
protein transport Hs biological process
membrane Hs cellular component
protein kinase binding Hs molecular function
protein kinase activator activity Hs molecular function
activation of protein kinase activity Hs biological process
negative regulation of protein catabolic process Hs biological process
negative regulation of apoptotic process Hs biological process
negative regulation of neuron apoptotic process Hs biological process
positive regulation of GTPase activity Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
positive regulation of JAK-STAT cascade Hs biological process
metal ion binding Hs molecular function
extracellular exosome Hs cellular component
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Hs biological process

GO (Blast)

15 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 477 2.54e-156
GTPase activity Hs molecular function 477 2.54e-156
GTPase activator activity Hs molecular function 477 2.54e-156
protein binding Hs molecular function 477 2.54e-156
GTP binding Hs molecular function 477 2.54e-156
phospholipid binding Hs molecular function 407 5.14e-128
nucleus Hs cellular component 305 9.66e-90
nucleolus Hs cellular component 305 9.66e-90
cytoplasm Hs cellular component 477 2.54e-156
mitochondrion Hs cellular component 305 9.66e-90
membrane Hs cellular component 477 2.54e-156
protein kinase binding Hs molecular function 305 9.66e-90
protein kinase activator activity Hs molecular function 305 9.66e-90
metal ion binding Hs molecular function 477 2.54e-156
extracellular exosome Hs cellular component 305 9.66e-90

GO (InterProScan)

4 results

GO Term Analysis Type e-value
GTPase activity Pfam molecular function 4.9E-15
GTPase activator activity SMART molecular function 2.4E-38
protein binding SMART molecular function 0.77
GTP binding Pfam molecular function 4.9E-15