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GENE CARD

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Gene Card

Best human hits

DOCK1; DOCK2; DOCK5

Species

H.roretzi

Unique Gene ID

Harore.g00000059

Gene Model ID

Harore.CG.MTP2014.S4.g00059

Location

S4:74789..92191

Transcript Models and Sequences

  Harore.CG.MTP2014.S4.g00059.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
DHR-1_domain ProSiteProfiles DHR-1 domain
SH3-like_dom_sf SUPERFAMILY SH3-like domain superfamily
ARM-type_fold SUPERFAMILY Armadillo-type fold
C2_domain_sf Gene3D C2 domain superfamily
DOCK PANTHER Dedicator of cytokinesis
DHR-2 ProSiteProfiles DHR-2 domain
DOCK_C Pfam Dedicator of cytokinesis, C-terminal
SH3_domain Pfam SH3 domain
SH3_domain SMART SH3 domain
DHR-1_domain Pfam DHR-1 domain
SH3_domain ProSiteProfiles SH3 domain
DOCK_N Pfam Dedicator of cytokinesis, N-terminal domain
DOCK1 PANTHER Dedicator of cytokinesis protein 1

GOSlim

40 results

GO Term Annotation Origin Type
GTPase activator activity Orthology molecular function
binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
intracellular Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
apoptotic process Orthology biological process
chemotaxis Orthology biological process
signal transduction Orthology biological process
small GTPase mediated signal transduction Orthology biological process
blood coagulation Orthology biological process
endomembrane system Orthology cellular component
membrane Orthology cellular component
cell migration Orthology biological process
nuclear speck Orthology cellular component
positive regulation of GTPase activity Orthology biological process
regulation of molecular function Orthology biological process
extracellular exosome Orthology cellular component
membrane organization Orthology biological process
animal organ development Orthology biological process
immune system process Orthology biological process
cell differentiation Orthology biological process
enzyme binding Orthology molecular function
molecular function regulator Orthology molecular function
organelle organization Orthology biological process
cell surface receptor signaling pathway Orthology biological process
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
intracellular organelle part Orthology cellular component
cytoplasmic vesicle Orthology cellular component
intracellular organelle lumen Orthology cellular component
cellular process Orthology biological process
receptor binding Orthology molecular function
macromolecular complex binding Orthology molecular function
cell morphogenesis involved in differentiation Orthology biological process
cell adhesion Orthology biological process

GO (Orthology)

41 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
membrane raft polarization Hs biological process
hematopoietic progenitor cell differentiation Hs biological process
guanyl-nucleotide exchange factor activity Hs molecular function
Rho guanyl-nucleotide exchange factor activity Hs molecular function
GTPase activator activity Hs molecular function
binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
plasma membrane Hs cellular component
phagocytosis Hs biological process
phagocytosis, engulfment Hs biological process
apoptotic process Hs biological process
chemotaxis Hs biological process
cytoskeleton organization Hs biological process
signal transduction Hs biological process
integrin-mediated signaling pathway Hs biological process
small GTPase mediated signal transduction Hs biological process
blood coagulation Hs biological process
endomembrane system Hs cellular component
membrane Hs cellular component
cell migration Hs biological process
nuclear speck Hs cellular component
SH3 domain binding Hs molecular function
actin cytoskeleton organization Hs biological process
Rac guanyl-nucleotide exchange factor activity Hs molecular function
guanyl-nucleotide exchange factor complex Hs cellular component
specific granule lumen Hs cellular component
T cell activation Hs biological process
T cell receptor binding Hs molecular function
positive regulation of GTPase activity Hs biological process
macropinocytosis Hs biological process
vascular endothelial growth factor receptor signaling pathway Hs biological process
positive regulation of phagocytosis Hs biological process
regulation of molecular function Hs biological process
extracellular exosome Hs cellular component
positive regulation of substrate adhesion-dependent cell spreading Hs biological process

GO (Blast)

21 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
guanyl-nucleotide exchange factor activity Hs molecular function 957 0.0
Rho guanyl-nucleotide exchange factor activity Hs molecular function 957 0.0
GTPase activator activity Hs molecular function 957 0.0
binding Hs molecular function 957 0.0
protein binding Hs molecular function 957 0.0
extracellular region Hs cellular component 900 0.0
intracellular Hs cellular component 900 0.0
nucleus Hs cellular component 957 0.0
cytoplasm Hs cellular component 957 0.0
cytosol Hs cellular component 957 0.0
cytoskeleton Hs cellular component 900 0.0
plasma membrane Hs cellular component 886 0.0
endomembrane system Hs cellular component 900 0.0
membrane Hs cellular component 957 0.0
nuclear speck Hs cellular component 957 0.0
SH3 domain binding Hs molecular function 957 0.0
Rac guanyl-nucleotide exchange factor activity Hs molecular function 900 0.0
guanyl-nucleotide exchange factor complex Hs cellular component 957 0.0
specific granule lumen Hs cellular component 900 0.0
T cell receptor binding Hs molecular function 900 0.0
extracellular exosome Hs cellular component 900 0.0

GO (InterProScan)

7 results

GO Term Analysis Type e-value
guanyl-nucleotide exchange factor activity PANTHER molecular function 0.0
GTPase activator activity PANTHER molecular function 0.0
binding SUPERFAMILY molecular function 6.62E-5
protein binding SMART molecular function 3.2E-12
cytoskeleton organization PANTHER biological process 0.0
small GTPase mediated signal transduction PANTHER biological process 0.0
cell migration PANTHER biological process 0.0

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