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Gene Card

Best human hits

RBPJ; RBPJL

Species

H.roretzi

Unique Gene ID

Harore.g00001677

Gene Model ID

Harore.CG.MTP2014.S3.g01677

Location

S3:180209..190743

Transcript Models and Sequences

  Harore.CG.MTP2014.S3.g01677.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
RBP-J/Cbf11/Cbf12_DNA-bd_sf Gene3D RBP-J/Cbf11/Cbf12, DNA binding domain superfamily
p53-like_TF_DNA-bd SUPERFAMILY p53-like transcription factor, DNA-binding
RBP-J/Cbf11/Cbf12_DNA-bd SMART RBP-J/Cbf11/Cbf12, DNA binding
Ig_E-set SUPERFAMILY Immunoglobulin E-set
Ig-like_fold Gene3D Immunoglobulin-like fold
RBP-Jkappa_IPT CDD RBP-Jkappa, IPT domain
Beta-trefoil_DNA-bd_dom SMART Beta-trefoil DNA-binding domain
RBP-J/Cbf11/Cbf12_DNA-bd Pfam RBP-J/Cbf11/Cbf12, DNA binding
BTD_sf SUPERFAMILY Beta-trefoil domain superfamily
Beta-trefoil_DNA-bd_dom Pfam Beta-trefoil DNA-binding domain

GOSlim

52 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Blast molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
angiogenesis Orthology biological process
DNA binding Orthology molecular function
chromatin binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
nucleolus Orthology cellular component
cytoplasm Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
Notch signaling pathway Orthology biological process
heart development Orthology biological process
transcription factor binding Orthology molecular function
positive regulation of cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
regulation of gene expression Orthology biological process
positive regulation of gene expression Orthology biological process
neuron differentiation Orthology biological process
regulation of cell proliferation Orthology biological process
sequence-specific DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
protein N-terminus binding Orthology molecular function
DNA metabolic process Orthology biological process
catalytic activity Orthology molecular function
anatomical structure formation involved in morphogenesis Orthology biological process
multicellular organism development Orthology biological process
animal organ development Orthology biological process
cell differentiation Orthology biological process
macromolecular complex Orthology cellular component
anatomical structure morphogenesis Orthology biological process
intracellular part Orthology cellular component
immune response Orthology biological process
anatomical structure development Orthology biological process
brain development Orthology biological process
immune system process Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
positive regulation of signal transduction Orthology biological process
developmental process Orthology biological process
blood vessel morphogenesis Orthology biological process
response to bacterium Orthology biological process
defense response Orthology biological process
blood vessel development Orthology biological process

GO (Orthology)

67 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
recombinase activity Hs molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
RNA polymerase II repressing transcription factor binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
angiogenesis Hs biological process
somitogenesis Hs biological process
epithelial to mesenchymal transition Hs biological process
MAML1-RBP-Jkappa- ICN1 complex Hs cellular component
outflow tract morphogenesis Hs biological process
endocardium development Hs biological process
endocardium morphogenesis Hs biological process
ventricular trabecula myocardium morphogenesis Hs biological process
DNA binding Hs molecular function
chromatin binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
nucleolus Hs cellular component
cytoplasm Hs cellular component
DNA recombination Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
humoral immune response Hs biological process
Notch signaling pathway Hs biological process
positive regulation of transcription of Notch receptor target Hs biological process
heart development Hs biological process
transcription factor binding Hs molecular function
positive regulation of cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
epidermal cell fate specification Hs biological process
regulation of gene expression Hs biological process
positive regulation of gene expression Hs biological process
transcriptional repressor complex Hs cellular component
pituitary gland development Hs biological process
hemopoiesis Hs biological process
neuron differentiation Hs biological process
B cell differentiation Hs biological process
keratinocyte differentiation Hs biological process
negative regulation of ossification Hs biological process
positive regulation of BMP signaling pathway Hs biological process
somatic stem cell population maintenance Hs biological process
dorsal aorta morphogenesis Hs biological process
atrioventricular canal development Hs biological process
regulation of cell proliferation Hs biological process
defense response to bacterium Hs biological process
myeloid dendritic cell differentiation Hs biological process
sequence-specific DNA binding Hs molecular function
cell fate commitment Hs biological process
negative regulation of cell differentiation Hs biological process
positive regulation of Notch signaling pathway Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
protein N-terminus binding Hs molecular function
regulation of timing of cell differentiation Hs biological process
artery morphogenesis Hs biological process
arterial endothelial cell fate commitment Hs biological process
repressing transcription factor binding Hs molecular function
blood vessel lumenization Hs biological process
blood vessel endothelial cell fate specification Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
recombinase activity Hs molecular function 763 0.0
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 482 1.91e-166
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 763 0.0
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 763 0.0
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 763 0.0
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 763 0.0
RNA polymerase II repressing transcription factor binding Hs molecular function 763 0.0
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 763 0.0
MAML1-RBP-Jkappa- ICN1 complex Hs cellular component 763 0.0
DNA binding Hs molecular function 763 0.0
chromatin binding Hs molecular function 763 0.0
transcription factor activity, sequence-specific DNA binding Hs molecular function 763 0.0
protein binding Hs molecular function 763 0.0
nucleus Hs cellular component 763 0.0
nucleoplasm Hs cellular component 763 0.0
transcription factor complex Hs cellular component 763 0.0
nucleolus Hs cellular component 763 0.0
cytoplasm Hs cellular component 763 0.0
transcription factor binding Hs molecular function 763 0.0
transcriptional repressor complex Hs cellular component 763 0.0
sequence-specific DNA binding Hs molecular function 763 0.0
protein N-terminus binding Hs molecular function 763 0.0
repressing transcription factor binding Hs molecular function 763 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
RNA polymerase II core promoter proximal region sequence-specific DNA binding SMART molecular function 2.5E-90
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding SMART molecular function 2.5E-90
DNA binding Gene3D molecular function 1.3E-165
transcription factor activity, sequence-specific DNA binding Gene3D molecular function 1.3E-165
nucleus Gene3D cellular component 1.3E-165
regulation of transcription, DNA-templated Gene3D biological process 1.3E-165

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