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Gene Card

Best human hits

IRAK1; IRAK3; IRAK4

Species

H.roretzi

Unique Gene ID

Harore.g00011159

Gene Model ID

Harore.CG.MTP2014.S29.g11159

Location

S29:321184..323797

Transcript Models and Sequences

  Harore.CG.MTP2014.S29.g11159.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Prot_kinase_dom SMART Protein kinase domain
DEATH-like_dom_sf SUPERFAMILY Death-like domain superfamily
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site

GOSlim

40 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
magnesium ion binding Blast molecular function
protein kinase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular space Blast cellular component
intracellular Blast cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
protein phosphorylation Orthology biological process
signal transduction Orthology biological process
membrane Blast cellular component
kinase activity Blast molecular function
transferase activity Blast molecular function
cytokine-mediated signaling pathway Orthology biological process
response to lipopolysaccharide Orthology biological process
protein homodimerization activity Orthology molecular function
innate immune response Orthology biological process
protein heterodimerization activity Orthology molecular function
intracellular signal transduction Orthology biological process
positive regulation of catalytic activity Orthology biological process
positive regulation of signal transduction Orthology biological process
cellular response to stress Orthology biological process
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
endosome Orthology cellular component
bounding membrane of organelle Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
regulation of molecular function Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
defense response Orthology biological process
enzyme regulator activity Blast molecular function
receptor binding Blast molecular function
intracellular non-membrane-bounded organelle Blast cellular component
integral component of plasma membrane Blast cellular component
macromolecular complex Blast cellular component

GO (Orthology)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
activation of MAPK activity Hs biological process
toll-like receptor signaling pathway Hs biological process
MyD88-dependent toll-like receptor signaling pathway Hs biological process
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
protein phosphorylation Hs biological process
signal transduction Hs biological process
JNK cascade Hs biological process
endosome membrane Hs cellular component
lipopolysaccharide-mediated signaling pathway Hs biological process
negative regulation of NF-kappaB transcription factor activity Hs biological process
toll-like receptor 9 signaling pathway Hs biological process
protein homodimerization activity Hs molecular function
protein heterodimerization activity Hs molecular function
positive regulation of NF-kappaB transcription factor activity Hs biological process
interleukin-1-mediated signaling pathway Hs biological process
inflammatory response Hs biological process
I-kappaB kinase/NF-kappaB signaling Hs biological process
intracellular signal transduction Hs biological process
negative regulation of sequence-specific DNA binding transcription factor activity Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 192 1.23e-51
magnesium ion binding Hs molecular function 158 2.19e-41
protein kinase activity Hs molecular function 192 1.23e-51
protein serine/threonine kinase activity Hs molecular function 192 1.23e-51
NF-kappaB-inducing kinase activity Hs molecular function 192 1.23e-51
interleukin-1 receptor binding Hs molecular function 158 2.19e-41
protein binding Hs molecular function 192 1.23e-51
ATP binding Hs molecular function 192 1.23e-51
extracellular space Hs cellular component 158 2.19e-41
intracellular Hs cellular component 158 2.19e-41
nucleus Hs cellular component 192 1.23e-51
cytoplasm Hs cellular component 192 1.23e-51
lipid droplet Hs cellular component 192 1.23e-51
cytosol Hs cellular component 192 1.23e-51
plasma membrane Hs cellular component 192 1.23e-51
endosome membrane Hs cellular component 192 1.23e-51
membrane Hs cellular component 192 1.23e-51
kinase activity Hs molecular function 192 1.23e-51
transferase activity Hs molecular function 192 1.23e-51
heat shock protein binding Hs molecular function 192 1.23e-51
protein homodimerization activity Hs molecular function 192 1.23e-51
interleukin-1 receptor complex Hs cellular component 192 1.23e-51
protein heterodimerization activity Hs molecular function 192 1.23e-51

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 7.2E-42
ATP binding Pfam molecular function 7.2E-42
protein phosphorylation Pfam biological process 7.2E-42

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