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GENE CARD

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Gene Card

Best human hits

ACLY; SUCLA2; SUCLG1

Species

H.roretzi

Unique Gene ID

Harore.g00000713

Gene Model ID

Harore.CG.MTP2014.S28.g00713

Location

S28:208188..217330

Transcript Models and Sequences

  Harore.CG.MTP2014.S28.g00713.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
Citrate_synth-like_sm_a-sub Gene3D Citrate synthase-like, small alpha subdomain
Cit_synth/succinyl-CoA_lig_AS ProSitePatterns ATP-citrate lyase/succinyl-CoA ligase, active site
CoA-bd Pfam CoA-binding
NAD(P)-bd_dom_sf SUPERFAMILY NAD(P)-binding domain superfamily
Succinyl-CoA_synth-like SUPERFAMILY Succinyl-CoA synthetase-like
Citrt_syn/SCS-alpha_CS ProSitePatterns ATP-citrate lyase/succinyl-CoA ligase, conserved site
Citrate-bd Pfam ATP-citrate synthase, citrate-binding domain
Citrate_synthase_sf SUPERFAMILY Citrate synthase superfamily
ATP-citrate_synthase PIRSF ATP-citrate synthase
ATP-grasp_succ-CoA_synth-type Pfam ATP-grasp fold, succinyl-CoA synthetase-type
CoA_ligase Pfam ATP-citrate lyase/succinyl-CoA ligase
Succinyl-CoA_synth-like Gene3D Succinyl-CoA synthetase-like
Succ-CoA_synthase_bsu_CS ProSitePatterns Succinyl-CoA synthetase, beta subunit, conserved site
Citrate_synthase Pfam Citrate synthase

GOSlim

36 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
magnesium ion binding Blast molecular function
RNA binding Blast molecular function
catalytic activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular region Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
mitochondrial inner membrane Blast cellular component
mitochondrial matrix Blast cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
metabolic process Orthology biological process
membrane Orthology cellular component
transferase activity Orthology molecular function
ligase activity Blast molecular function
myelin sheath Blast cellular component
metal ion binding Orthology molecular function
cofactor binding Orthology molecular function
extracellular exosome Orthology cellular component
phosphate-containing compound metabolic process Orthology biological process
amide biosynthetic process Orthology biological process
cellular metabolic process Orthology biological process
organic substance metabolic process Orthology biological process
cellular biosynthetic process Orthology biological process
cytoplasmic part Orthology cellular component
macromolecular complex Orthology cellular component
nucleobase-containing compound metabolic process Orthology biological process
cytoplasmic vesicle Orthology cellular component
lysosome Orthology cellular component
vacuolar part Orthology cellular component
endomembrane system Orthology cellular component
intracellular organelle lumen Orthology cellular component
intracellular organelle part Orthology cellular component

GO (Orthology)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
catalytic activity Hs molecular function
ATP citrate synthase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
extracellular region Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
acetyl-CoA biosynthetic process Hs biological process
citrate metabolic process Hs biological process
oxaloacetate metabolic process Hs biological process
lipid metabolic process Hs biological process
fatty acid biosynthetic process Hs biological process
cholesterol biosynthetic process Hs biological process
metabolic process Hs biological process
lipid biosynthetic process Hs biological process
citrate lyase complex Hs cellular component
coenzyme A metabolic process Hs biological process
membrane Hs cellular component
transferase activity Hs molecular function
lyase activity Hs molecular function
azurophil granule lumen Hs cellular component
metal ion binding Hs molecular function
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Hs molecular function
cofactor binding Hs molecular function
extracellular exosome Hs cellular component
ficolin-1-rich granule lumen Hs cellular component

GO (Blast)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 1655 0.0
magnesium ion binding Hs molecular function 58.2 1.66e-08
RNA binding Hs molecular function 59.3 5.57e-09
catalytic activity Hs molecular function 1655 0.0
ATP citrate synthase activity Hs molecular function 1655 0.0
succinate-CoA ligase (ADP-forming) activity Hs molecular function 59.3 5.57e-09
succinate-CoA ligase (GDP-forming) activity Hs molecular function 59.3 5.57e-09
protein binding Hs molecular function 1655 0.0
ATP binding Hs molecular function 1655 0.0
extracellular region Hs cellular component 1655 0.0
nucleoplasm Hs cellular component 1655 0.0
cytoplasm Hs cellular component 1655 0.0
mitochondrion Hs cellular component 59.3 5.57e-09
mitochondrial inner membrane Hs cellular component 59.3 5.57e-09
mitochondrial matrix Hs cellular component 59.3 5.57e-09
cytosol Hs cellular component 1655 0.0
plasma membrane Hs cellular component 1655 0.0
citrate lyase complex Hs cellular component 1655 0.0
membrane Hs cellular component 1655 0.0
transferase activity Hs molecular function 1655 0.0
lyase activity Hs molecular function 1655 0.0
ligase activity Hs molecular function 59.3 5.57e-09
azurophil granule lumen Hs cellular component 1655 0.0
myelin sheath Hs cellular component 58.2 1.66e-08
metal ion binding Hs molecular function 1655 0.0
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Hs molecular function 1655 0.0
cofactor binding Hs molecular function 1655 0.0
extracellular exosome Hs cellular component 1655 0.0
ficolin-1-rich granule lumen Hs cellular component 1655 0.0

GO (InterProScan)

7 results

GO Term Analysis Type e-value
catalytic activity Pfam molecular function 4.7E-16
ATP citrate synthase activity PIRSF molecular function 0.0
acetyl-CoA biosynthetic process PIRSF biological process 0.0
citrate metabolic process PIRSF biological process 0.0
metabolic process Pfam biological process 4.7E-16
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer SUPERFAMILY molecular function 1.18E-74
cofactor binding Pfam molecular function 7.9E-11