Gene Card
Best human hits
TP53; TP63; TP73
Species
Unique Gene ID
Harore.g00006040
Gene Model ID
Harore.CG.MTP2014.S231.g06040
Location
S231:138224..139502
Transcript Models and Sequences
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
9 results
| IPR Term | Analysis | Definition |
|---|---|---|
| p53/RUNT-type_TF_DNA-bd_sf | Gene3D | p53/RUNT-type transcription factor, DNA-binding domain superfamily |
| p53_tumour_suppressor | PRINTS | p53 tumour suppressor family |
| p53_tumour_suppressor | PANTHER | p53 tumour suppressor family |
| p53_DNA-bd | CDD | p53, DNA-binding domain |
| p53-like_TF_DNA-bd | SUPERFAMILY | p53-like transcription factor, DNA-binding |
| p53_tetrameristn | Pfam | p53, tetramerisation domain |
| p53_tetramer_sf | Gene3D | p53-like tetramerisation domain superfamily |
| p53_tetramer_sf | SUPERFAMILY | p53-like tetramerisation domain superfamily |
| p53_DNA-bd | Pfam | p53, DNA-binding domain |
GOSlim
51 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | Blast | molecular function |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
| transcription factor activity, transcription factor binding | Blast | molecular function |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | Blast | molecular function |
| DNA binding | Blast | molecular function |
| chromatin binding | Blast | molecular function |
| double-stranded DNA binding | Blast | molecular function |
| transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| ATP binding | Blast | molecular function |
| intracellular | Blast | cellular component |
| nucleus | Blast | cellular component |
| nucleoplasm | Blast | cellular component |
| nucleolus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| mitochondrion | Blast | cellular component |
| mitochondrial matrix | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| cytosol | Blast | cellular component |
| regulation of transcription, DNA-templated | InterProScan | biological process |
| apoptotic process | InterProScan | biological process |
| transcription factor binding | Blast | molecular function |
| zinc ion binding | Blast | molecular function |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| nuclear body | Blast | cellular component |
| enzyme binding | Blast | molecular function |
| protein kinase binding | Blast | molecular function |
| cell junction | Blast | cellular component |
| ubiquitin protein ligase binding | Blast | molecular function |
| macromolecular complex | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| neuron projection | Blast | cellular component |
| intracellular membrane-bounded organelle | Blast | cellular component |
| sequence-specific DNA binding | Blast | molecular function |
| transcription regulatory region DNA binding | Blast | molecular function |
| metal ion binding | Blast | molecular function |
| protein heterodimerization activity | Blast | molecular function |
| protein N-terminus binding | Blast | molecular function |
| intracellular organelle part | Blast | cellular component |
| intracellular non-membrane-bounded organelle | Blast | cellular component |
| nuclear lumen | Blast | cellular component |
| transcription regulatory region sequence-specific DNA binding | Blast | molecular function |
| macromolecular complex binding | Blast | molecular function |
| RNA binding | Blast | molecular function |
| transition metal ion binding | Blast | molecular function |
| intracellular part | Blast | cellular component |
| nucleoplasm part | Blast | cellular component |
| receptor binding | Blast | molecular function |
| protein oligomerization | InterProScan | biological process |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
70 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| chromatin | Hs | cellular component | 191 | 2.28e-54 |
| nuclear chromatin | Hs | cellular component | 197 | 1.12e-56 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 191 | 2.28e-54 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 197 | 1.12e-56 |
| transcription factor activity, transcription factor binding | Hs | molecular function | 197 | 1.12e-56 |
| transcription factor activity, core RNA polymerase binding | Hs | molecular function | 158 | 4.93e-44 |
| core promoter sequence-specific DNA binding | Hs | molecular function | 158 | 4.93e-44 |
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly | Hs | molecular function | 158 | 4.93e-44 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | Hs | molecular function | 197 | 1.12e-56 |
| transcription factor activity, TFIID-class binding | Hs | molecular function | 158 | 4.93e-44 |
| RNA polymerase II transcription factor binding | Hs | molecular function | 158 | 4.93e-44 |
| TFIID-class transcription factor binding | Hs | molecular function | 158 | 4.93e-44 |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | Hs | molecular function | 158 | 4.93e-44 |
| protease binding | Hs | molecular function | 158 | 4.93e-44 |
| p53 binding | Hs | molecular function | 197 | 1.12e-56 |
| DNA binding | Hs | molecular function | 197 | 1.12e-56 |
| chromatin binding | Hs | molecular function | 197 | 1.12e-56 |
| damaged DNA binding | Hs | molecular function | 197 | 1.12e-56 |
| double-stranded DNA binding | Hs | molecular function | 197 | 1.12e-56 |
| transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 197 | 1.12e-56 |
| mRNA 3'-UTR binding | Hs | molecular function | 158 | 4.93e-44 |
| copper ion binding | Hs | molecular function | 158 | 4.93e-44 |
| protein binding | Hs | molecular function | 197 | 1.12e-56 |
| ATP binding | Hs | molecular function | 158 | 4.93e-44 |
| intracellular | Hs | cellular component | 158 | 4.93e-44 |
| nucleus | Hs | cellular component | 197 | 1.12e-56 |
| nucleoplasm | Hs | cellular component | 197 | 1.12e-56 |
| replication fork | Hs | cellular component | 158 | 4.93e-44 |
| transcription factor complex | Hs | cellular component | 197 | 1.12e-56 |
| transcription factor TFIID complex | Hs | cellular component | 158 | 4.93e-44 |
| nucleolus | Hs | cellular component | 158 | 4.93e-44 |
| cytoplasm | Hs | cellular component | 197 | 1.12e-56 |
| mitochondrion | Hs | cellular component | 197 | 1.12e-56 |
| mitochondrial matrix | Hs | cellular component | 158 | 4.93e-44 |
| endoplasmic reticulum | Hs | cellular component | 158 | 4.93e-44 |
| rough endoplasmic reticulum | Hs | cellular component | 197 | 1.12e-56 |
| Golgi apparatus | Hs | cellular component | 197 | 1.12e-56 |
| cytosol | Hs | cellular component | 197 | 1.12e-56 |
| transcription factor binding | Hs | molecular function | 191 | 2.28e-54 |
| zinc ion binding | Hs | molecular function | 158 | 4.93e-44 |
| membrane | Hs | cellular component | 158 | 4.93e-44 |
| integral component of membrane | Hs | cellular component | 158 | 4.93e-44 |
| nuclear matrix | Hs | cellular component | 158 | 4.93e-44 |
| nuclear body | Hs | cellular component | 158 | 4.93e-44 |
| PML body | Hs | cellular component | 158 | 4.93e-44 |
| enzyme binding | Hs | molecular function | 158 | 4.93e-44 |
| protein kinase binding | Hs | molecular function | 191 | 2.28e-54 |
| protein phosphatase binding | Hs | molecular function | 158 | 4.93e-44 |
| protein domain specific binding | Hs | molecular function | 197 | 1.12e-56 |
| cell junction | Hs | cellular component | 191 | 2.28e-54 |
| dendrite | Hs | cellular component | 197 | 1.12e-56 |
| receptor tyrosine kinase binding | Hs | molecular function | 158 | 4.93e-44 |
| ubiquitin protein ligase binding | Hs | molecular function | 158 | 4.93e-44 |
| macromolecular complex | Hs | cellular component | 158 | 4.93e-44 |
| histone acetyltransferase binding | Hs | molecular function | 158 | 4.93e-44 |
| identical protein binding | Hs | molecular function | 197 | 1.12e-56 |
| histone deacetylase binding | Hs | molecular function | 158 | 4.93e-44 |
| neuron projection | Hs | cellular component | 197 | 1.12e-56 |
| intracellular membrane-bounded organelle | Hs | cellular component | 191 | 2.28e-54 |
| sequence-specific DNA binding | Hs | molecular function | 197 | 1.12e-56 |
| protein self-association | Hs | molecular function | 158 | 4.93e-44 |
| transcription regulatory region DNA binding | Hs | molecular function | 197 | 1.12e-56 |
| metal ion binding | Hs | molecular function | 197 | 1.12e-56 |
| protein heterodimerization activity | Hs | molecular function | 158 | 4.93e-44 |
| protein N-terminus binding | Hs | molecular function | 158 | 4.93e-44 |
| WW domain binding | Hs | molecular function | 197 | 1.12e-56 |
| chaperone binding | Hs | molecular function | 158 | 4.93e-44 |
| protein phosphatase 2A binding | Hs | molecular function | 158 | 4.93e-44 |
| MDM2/MDM4 family protein binding | Hs | molecular function | 197 | 1.12e-56 |
| disordered domain specific binding | Hs | molecular function | 158 | 4.93e-44 |
GO (InterProScan)
7 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| DNA binding | PANTHER | molecular function | 4.0E-81 |
| transcription factor activity, sequence-specific DNA binding | PANTHER | molecular function | 4.0E-81 |
| nucleus | PANTHER | cellular component | 4.0E-81 |
| regulation of transcription, DNA-templated | PANTHER | biological process | 4.0E-81 |
| apoptotic process | PANTHER | biological process | 4.0E-81 |
| transcription regulatory region DNA binding | CDD | molecular function | 2.19332E-66 |
| protein tetramerization | Gene3D | biological process | 8.7E-12 |
