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GENE CARD

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Gene Card

Best human hits

EIF4G1; EIF4G2; EIF4G3

Species

H.roretzi

Unique Gene ID

Harore.g00008668

Gene Model ID

Harore.CG.MTP2014.S188.g08668

Location

S188:16830..35979

Transcript Models and Sequences

  Harore.CG.MTP2014.S188.g08668.01.t
Harore.CG.MTP2014.S188.g08668.02.t
Harore.CG.MTP2014.S188.g08668.03.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
W2_domain ProSiteProfiles W2 domain
ARM-type_fold SUPERFAMILY Armadillo-type fold
MIF4-like_sf Gene3D MIF4G-like domain superfamily
EIF4G1 PANTHER Eukaryotic translation initiation factor 4 gamma 1
W2_domain Pfam W2 domain
MIF4G-like_typ-3 SMART MIF4G-like, type 3
W2_domain SMART W2 domain
Initiation_fac_eIF4g_MI ProSiteProfiles Initiation factor eIF-4 gamma, MA3
Initiation_fac_eIF4g_MI Pfam Initiation factor eIF-4 gamma, MA3
MIF4G-like_typ-3 Pfam MIF4G-like, type 3
Initiation_fac_eIF4g_MI SMART Initiation factor eIF-4 gamma, MA3
EIF4G3 PANTHER Eukaryotic translation initiation factor 4 gamma 3

GOSlim

35 results

GO Term Annotation Origin Type
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Orthology biological process
RNA binding Orthology molecular function
binding Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
nucleus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
translational initiation Orthology biological process
positive regulation of cell proliferation Orthology biological process
positive regulation of cell death Orthology biological process
membrane Orthology cellular component
axon Blast cellular component
developmental process Orthology biological process
identical protein binding Orthology molecular function
nuclear-transcribed mRNA catabolic process Orthology biological process
regulation of gene expression Orthology biological process
macromolecular complex Orthology cellular component
organelle organization Orthology biological process
cytoplasmic part Orthology cellular component
intracellular organelle part Orthology cellular component
ribosome Orthology cellular component
cellular component organization Orthology biological process
cell communication Orthology biological process
protein phosphorylation Orthology biological process
mRNA catabolic process Orthology biological process
cell adhesion molecule binding Orthology molecular function
cell development Orthology biological process
neuron differentiation Orthology biological process
negative regulation of gene expression Orthology biological process
cellular response to stress Orthology biological process
G1/S transition of mitotic cell cycle Orthology biological process
negative regulation of cell death Orthology biological process
nervous system development Orthology biological process
adherens junction Blast cellular component

GO (Orthology)

44 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Hs biological process
nuclear-transcribed mRNA poly(A) tail shortening Hs biological process
RNA cap binding Hs molecular function
cap-dependent translational initiation Hs biological process
RNA binding Hs molecular function
mRNA binding Hs molecular function
translation initiation factor activity Hs molecular function
binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
polysome Hs cellular component
translation Hs biological process
translational initiation Hs biological process
regulation of translation Hs biological process
regulation of translational initiation Hs biological process
mitochondrion organization Hs biological process
translation factor activity, RNA binding Hs molecular function
eukaryotic initiation factor 4E binding Hs molecular function
positive regulation of cell proliferation Hs biological process
negative regulation of autophagy Hs biological process
positive regulation of cell death Hs biological process
membrane Hs cellular component
viral process Hs biological process
eukaryotic translation initiation factor 4F complex Hs cellular component
cytosolic small ribosomal subunit Hs cellular component
positive regulation of cell growth Hs biological process
translation initiation factor binding Hs molecular function
cellular response to nutrient levels Hs biological process
developmental process Hs biological process
protein complex scaffold activity Hs molecular function
positive regulation of peptidyl-serine phosphorylation Hs biological process
identical protein binding Hs molecular function
regulation of mRNA stability Hs biological process
cadherin binding Hs molecular function
positive regulation of neuron differentiation Hs biological process
regulation of gene silencing by miRNA Hs biological process
regulation of cellular response to stress Hs biological process
energy homeostasis Hs biological process
positive regulation of G1/S transition of mitotic cell cycle Hs biological process
negative regulation of neuron death Hs biological process
regulation of presynapse assembly Hs biological process

GO (Blast)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA cap binding Hs molecular function 671 0.0
RNA binding Hs molecular function 671 0.0
mRNA binding Hs molecular function 631 0.0
translation initiation factor activity Hs molecular function 671 0.0
binding Hs molecular function 671 0.0
protein binding Hs molecular function 671 0.0
ATP binding Hs molecular function 631 0.0
nucleus Hs cellular component 631 0.0
cytoplasm Hs cellular component 631 0.0
cytosol Hs cellular component 671 0.0
polysome Hs cellular component 631 0.0
cell-cell adherens junction Hs cellular component 232 1.52e-62
translation factor activity, RNA binding Hs molecular function 671 0.0
eukaryotic initiation factor 4E binding Hs molecular function 631 0.0
membrane Hs cellular component 631 0.0
eukaryotic translation initiation factor 4F complex Hs cellular component 671 0.0
cytosolic small ribosomal subunit Hs cellular component 631 0.0
axon Hs cellular component 232 1.52e-62
translation initiation factor binding Hs molecular function 631 0.0
protein complex scaffold activity Hs molecular function 631 0.0
identical protein binding Hs molecular function 631 0.0
cadherin binding Hs molecular function 631 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
RNA cap binding PANTHER molecular function 2.1E-46
RNA binding Pfam molecular function 1.2E-54
mRNA binding PANTHER molecular function 2.2E-244
translation initiation factor activity PANTHER molecular function 2.2E-244
binding SUPERFAMILY molecular function 2.09E-64
protein binding SMART molecular function 1.4E-18

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