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GENE CARD

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Gene Card

Best human hits

ARFGEF1; ARFGEF2; GBF1

Species

H.roretzi

Unique Gene ID

Harore.g00008562

Gene Model ID

Harore.CG.MTP2014.S16.g08562

Location

S16:226881..242272

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

9 results

IPR Term Analysis Definition
ARM-type_fold SUPERFAMILY Armadillo-type fold
Sec7_dom ProSiteProfiles Sec7 domain
Sec7_dom Pfam Sec7 domain
Sec7_C_sf Gene3D Sec7, C-terminal domain superfamily
DCB_dom Pfam Mon2, dimerisation and cyclophilin-binding domain
Sec7_dom SMART Sec7 domain
Sec7_N Pfam Guanine nucleotide exchange factor, N-terminal
Sec7_C Pfam Sec7, C-terminal
Sec7_dom_sf SUPERFAMILY Sec7 domain superfamily

GOSlim

51 results

GO Term Annotation Origin Type
Golgi membrane Orthology cellular component
binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
nucleolus Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
endosome Orthology cellular component
peroxisome Blast cellular component
endoplasmic reticulum lumen Blast cellular component
Golgi apparatus Orthology cellular component
microtubule organizing center Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
protein transport Orthology biological process
membrane Orthology cellular component
cell junction Orthology cellular component
neuron projection development Orthology biological process
cell leading edge Blast cellular component
cytoplasmic vesicle Orthology cellular component
intracellular signal transduction Orthology biological process
cell projection Orthology cellular component
synapse Orthology cellular component
perinuclear region of cytoplasm Orthology cellular component
regulation of molecular function Orthology biological process
membrane organization Orthology biological process
organelle organization Orthology biological process
enzyme binding Orthology molecular function
molecular function regulator Orthology molecular function
Golgi apparatus part Orthology cellular component
cell projection part Orthology cellular component
microtubule Orthology cellular component
macromolecular complex Orthology cellular component
cytoplasmic part Orthology cellular component
plasma membrane region Orthology cellular component
nuclear lumen Orthology cellular component
cytoskeletal protein binding Orthology molecular function
nuclear part Orthology cellular component
small GTPase mediated signal transduction Orthology biological process
regulation of signal transduction Orthology biological process
organelle Orthology cellular component
postsynapse Orthology cellular component
neuron part Orthology cellular component
regulation of GTPase activity Orthology biological process
receptor binding Orthology molecular function
positive regulation of signal transduction Orthology biological process
wound healing Orthology biological process
anion binding Blast molecular function
intracellular membrane-bounded organelle Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component

GO (Orthology)

47 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
Golgi membrane Hs cellular component
receptor recycling Hs biological process
guanyl-nucleotide exchange factor activity Hs molecular function
ARF guanyl-nucleotide exchange factor activity Hs molecular function
binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
nucleolus Hs cellular component
cytoplasm Hs cellular component
endosome Hs cellular component
Golgi apparatus Hs cellular component
trans-Golgi network Hs cellular component
microtubule organizing center Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
axonemal microtubule Hs cellular component
exocytosis Hs biological process
Golgi to plasma membrane transport Hs biological process
Golgi organization Hs biological process
endosome organization Hs biological process
protein transport Hs biological process
membrane Hs cellular component
nuclear matrix Hs cellular component
myosin binding Hs molecular function
cell junction Hs cellular component
dendrite Hs cellular component
small nuclear ribonucleoprotein complex Hs cellular component
negative regulation of actin filament polymerization Hs biological process
neuron projection development Hs biological process
cytoplasmic vesicle Hs cellular component
regulation of ARF protein signal transduction Hs biological process
asymmetric synapse Hs cellular component
symmetric synapse Hs cellular component
protein kinase A regulatory subunit binding Hs molecular function
negative regulation of GTPase activity Hs biological process
intracellular signal transduction Hs biological process
cell projection Hs cellular component
dendritic spine Hs cellular component
synapse Hs cellular component
perinuclear region of cytoplasm Hs cellular component
GABA receptor binding Hs molecular function
positive regulation of protein kinase B signaling Hs biological process
recycling endosome Hs cellular component
regulation of molecular function Hs biological process
positive regulation of wound healing Hs biological process
regulation of establishment of cell polarity Hs biological process

GO (Blast)

43 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
Golgi membrane Hs cellular component 1877 0.0
guanyl-nucleotide exchange factor activity Hs molecular function 1877 0.0
ARF guanyl-nucleotide exchange factor activity Hs molecular function 1877 0.0
binding Hs molecular function 1877 0.0
protein binding Hs molecular function 1877 0.0
phosphatidylinositol-3,4,5-trisphosphate binding Hs molecular function 221 7.72e-58
nucleus Hs cellular component 1753 0.0
nucleoplasm Hs cellular component 1753 0.0
nucleolus Hs cellular component 1753 0.0
cytoplasm Hs cellular component 1877 0.0
mitochondrion Hs cellular component 221 7.72e-58
endosome Hs cellular component 1877 0.0
peroxisome Hs cellular component 221 7.72e-58
endoplasmic reticulum lumen Hs cellular component 221 7.72e-58
endoplasmic reticulum-Golgi intermediate compartment Hs cellular component 221 7.72e-58
Golgi apparatus Hs cellular component 1877 0.0
Golgi stack Hs cellular component 221 7.72e-58
cis-Golgi network Hs cellular component 221 7.72e-58
trans-Golgi network Hs cellular component 1877 0.0
lipid droplet Hs cellular component 221 7.72e-58
microtubule organizing center Hs cellular component 1877 0.0
cytosol Hs cellular component 1877 0.0
cytoskeleton Hs cellular component 1877 0.0
axonemal microtubule Hs cellular component 1877 0.0
lipid binding Hs molecular function 221 7.72e-58
membrane Hs cellular component 1877 0.0
nuclear matrix Hs cellular component 1753 0.0
myosin binding Hs molecular function 1877 0.0
cell junction Hs cellular component 1877 0.0
dendrite Hs cellular component 1877 0.0
small nuclear ribonucleoprotein complex Hs cellular component 1753 0.0
cell leading edge Hs cellular component 221 7.72e-58
cytoplasmic vesicle Hs cellular component 1877 0.0
asymmetric synapse Hs cellular component 1877 0.0
symmetric synapse Hs cellular component 1877 0.0
protein kinase A regulatory subunit binding Hs molecular function 1877 0.0
cell projection Hs cellular component 1877 0.0
dendritic spine Hs cellular component 1877 0.0
synapse Hs cellular component 1877 0.0
perinuclear region of cytoplasm Hs cellular component 1877 0.0
GABA receptor binding Hs molecular function 1877 0.0
recycling endosome Hs cellular component 1877 0.0
phosphatidylinositol-3,5-bisphosphate binding Hs molecular function 221 7.72e-58

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ARF guanyl-nucleotide exchange factor activity SMART molecular function 9.3E-93
binding SUPERFAMILY molecular function 2.04E-20
regulation of ARF protein signal transduction SMART biological process 9.3E-93