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Gene Card

Best human hits

DDR1; DDR2

Species

H.roretzi

Unique Gene ID

Harore.g00012348

Gene Model ID

Harore.CG.MTP2014.S125.g12348

Location

S125:162900..173816

Transcript Models and Sequences

  Harore.CG.MTP2014.S125.g12348.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
Tyr_kinase_cat_dom SMART Tyrosine-protein kinase, catalytic domain
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Ser-Thr/Tyr_kinase_cat_dom PRINTS Serine-threonine/tyrosine-protein kinase, catalytic domain
FA58C ProSiteProfiles Coagulation factor 5/8 C-terminal domain
FA58C ProSitePatterns Coagulation factor 5/8 C-terminal domain
Tyr_kinase_AS ProSitePatterns Tyrosine-protein kinase, active site
Galactose-bd-like_sf Gene3D Galactose-binding-like domain superfamily
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Galactose-bd-like_sf SUPERFAMILY Galactose-binding-like domain superfamily
DDR1 PANTHER Epithelial discoidin domain-containing receptor 1
FA58C Pfam Coagulation factor 5/8 C-terminal domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily

GOSlim

40 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
protein kinase activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
protein phosphorylation Orthology biological process
cell adhesion Orthology biological process
signal transduction Orthology biological process
positive regulation of cell proliferation Orthology biological process
membrane Orthology cellular component
integral component of membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
apical plasma membrane Orthology cellular component
transferase activity Orthology molecular function
extracellular matrix organization Orthology biological process
protein autophosphorylation Orthology biological process
metal ion binding Orthology molecular function
extracellular exosome Orthology cellular component
negative regulation of cell proliferation Orthology biological process
axon development Orthology biological process
transmembrane signaling receptor activity Orthology molecular function
macromolecular complex binding Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
cytoskeleton Orthology cellular component
animal organ development Orthology biological process
cell proliferation Orthology biological process
macromolecular complex Orthology cellular component
cell migration Orthology biological process
wound healing Orthology biological process
anatomical structure morphogenesis Orthology biological process
cell differentiation Orthology biological process
positive regulation of catalytic activity Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
cellular component organization Orthology biological process
neuron projection morphogenesis Orthology biological process

GO (Orthology)

47 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
ossification Hs biological process
protein kinase activity Hs molecular function
protein tyrosine kinase activity Hs molecular function
transmembrane receptor protein tyrosine kinase activity Hs molecular function
protein binding Hs molecular function
collagen binding Hs molecular function
ATP binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
focal adhesion Hs cellular component
protein phosphorylation Hs biological process
cell adhesion Hs biological process
signal transduction Hs biological process
transmembrane receptor protein tyrosine kinase signaling pathway Hs biological process
positive regulation of cell proliferation Hs biological process
actin cytoskeleton Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
apical plasma membrane Hs cellular component
transferase activity Hs molecular function
peptidyl-tyrosine phosphorylation Hs biological process
extracellular matrix organization Hs biological process
collagen fibril organization Hs biological process
regulation of bone mineralization Hs biological process
chondrocyte proliferation Hs biological process
protein tyrosine kinase collagen receptor activity Hs molecular function
collagen-activated tyrosine kinase receptor signaling pathway Hs biological process
peptidyl-tyrosine autophosphorylation Hs biological process
receptor complex Hs cellular component
wound healing, spreading of cells Hs biological process
positive regulation of osteoblast differentiation Hs biological process
positive regulation of protein kinase activity Hs biological process
protein autophosphorylation Hs biological process
metal ion binding Hs molecular function
positive regulation of sequence-specific DNA binding transcription factor activity Hs biological process
extracellular exosome Hs cellular component
regulation of cell growth Hs biological process
regulation of cell-matrix adhesion Hs biological process
negative regulation of cell proliferation Hs biological process
ear development Hs biological process
axon development Hs biological process
neuron projection extension Hs biological process

GO (Blast)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 584 0.0
protein kinase activity Hs molecular function 584 0.0
protein tyrosine kinase activity Hs molecular function 584 0.0
transmembrane receptor protein tyrosine kinase activity Hs molecular function 584 0.0
protein binding Hs molecular function 584 0.0
collagen binding Hs molecular function 584 0.0
ATP binding Hs molecular function 584 0.0
extracellular region Hs cellular component 382 1.93e-117
extracellular space Hs cellular component 382 1.93e-117
plasma membrane Hs cellular component 584 0.0
integral component of plasma membrane Hs cellular component 584 0.0
focal adhesion Hs cellular component 584 0.0
actin cytoskeleton Hs cellular component 584 0.0
membrane Hs cellular component 584 0.0
integral component of membrane Hs cellular component 584 0.0
kinase activity Hs molecular function 584 0.0
apical plasma membrane Hs cellular component 584 0.0
transferase activity Hs molecular function 584 0.0
protein tyrosine kinase collagen receptor activity Hs molecular function 584 0.0
receptor complex Hs cellular component 382 1.93e-117
metal ion binding Hs molecular function 382 1.93e-117
extracellular exosome Hs cellular component 584 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 4.6E-82
protein tyrosine kinase activity SMART molecular function 2.3E-115
ATP binding ProSiteProfiles molecular function 35.128
integral component of plasma membrane PANTHER cellular component 2.1E-214
protein phosphorylation SMART biological process 2.3E-115
protein tyrosine kinase collagen receptor activity PANTHER molecular function 2.1E-214

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