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Gene Card

Best human hits

BMP2; BMP4; NODAL

Species

H.aurantium

Unique Gene ID

Haaura.g00001372

Gene Model ID

Haaura.CG.MTP2014.S56.g01372

Location

S56:111072..113278

Transcript Models and Sequences

  Haaura.CG.MTP2014.S56.g01372.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
TGF-beta-rel PANTHER Transforming growth factor-beta-related
TGFb_CS ProSitePatterns Transforming growth factor beta, conserved site
TGF-b_C SMART Transforming growth factor-beta, C-terminal
TGF-b_C Pfam Transforming growth factor-beta, C-terminal
TGF-b_C ProSiteProfiles Transforming growth factor-beta, C-terminal
Cystine-knot_cytokine Gene3D Cystine-knot cytokine
Cystine-knot_cytokine SUPERFAMILY Cystine-knot cytokine

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

59 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
gastrulation with mouth forming second Hs biological process
mesoderm formation Hs biological process
liver development Hs biological process
vasculature development Hs biological process
heart looping Hs biological process
cytokine activity Hs molecular function
transforming growth factor beta receptor binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
multicellular organism development Hs biological process
determination of left/right symmetry Hs biological process
gastrulation Hs biological process
nervous system development Hs biological process
brain development Hs biological process
endoderm development Hs biological process
heart development Hs biological process
growth factor activity Hs molecular function
positive regulation of cell proliferation Hs biological process
embryonic pattern specification Hs biological process
anterior/posterior axis specification Hs biological process
anterior/posterior pattern specification Hs biological process
regulation of signal transduction Hs biological process
polarity specification of proximal/distal axis Hs biological process
regulation of receptor activity Hs biological process
regulation of gastrulation Hs biological process
positive regulation of vascular endothelial growth factor production Hs biological process
positive regulation of pathway-restricted SMAD protein phosphorylation Hs biological process
morphogen activity Hs molecular function
cell migration Hs biological process
stem cell population maintenance Hs biological process
positive regulation of cell-cell adhesion Hs biological process
lung development Hs biological process
BMP signaling pathway Hs biological process
positive regulation of activin receptor signaling pathway Hs biological process
embryonic heart tube development Hs biological process
endodermal cell differentiation Hs biological process
nodal signaling pathway Hs biological process
cell migration involved in gastrulation Hs biological process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
cell fate commitment Hs biological process
negative regulation of cell differentiation Hs biological process
positive regulation of angiogenesis Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
receptor ligand activity Hs molecular function
mesendoderm development Hs biological process
cell development Hs biological process
digestive tract morphogenesis Hs biological process
anatomical structure formation involved in morphogenesis Hs biological process
embryonic cranial skeleton morphogenesis Hs biological process
tissue morphogenesis Hs biological process
formation of anatomical boundary Hs biological process
positive regulation of epithelial cell proliferation Hs biological process
positive regulation of sequence-specific DNA binding transcription factor activity Hs biological process
digestive system development Hs biological process
SMAD protein signal transduction Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
type I activin receptor binding Hs molecular function
primitive streak formation Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
retinol dehydrogenase activity Hs molecular function 108 3.58e-26
receptor binding Hs molecular function 108 3.58e-26
cytokine activity Hs molecular function 140 5.62e-38
transforming growth factor beta receptor binding Hs molecular function 140 5.62e-38
protein binding Hs molecular function 108 3.58e-26
extracellular region Hs cellular component 140 5.62e-38
proteinaceous extracellular matrix Hs cellular component 106 3.28e-25
extracellular space Hs cellular component 140 5.62e-38
endoplasmic reticulum lumen Hs cellular component 106 3.28e-25
growth factor activity Hs molecular function 140 5.62e-38
heparin binding Hs molecular function 106 3.28e-25
cell surface Hs cellular component 108 3.58e-26
morphogen activity Hs molecular function 140 5.62e-38
phosphatase activator activity Hs molecular function 108 3.58e-26
co-receptor binding Hs molecular function 108 3.58e-26
chemoattractant activity Hs molecular function 106 3.28e-25
intracellular membrane-bounded organelle Hs cellular component 108 3.58e-26
SMAD binding Hs molecular function 108 3.58e-26
protein heterodimerization activity Hs molecular function 108 3.58e-26
receptor ligand activity Hs molecular function 140 5.62e-38
type I activin receptor binding Hs molecular function 140 5.62e-38
BMP receptor binding Hs molecular function 108 3.58e-26
BMP receptor complex Hs cellular component 108 3.58e-26

GO (InterProScan)

1 result

GO Term Analysis Type e-value
growth factor activity SMART molecular function 1.3E-48

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