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GENE CARD

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Gene Card

Best human hits

USP40; USP47; USP7

Species

H.aurantium

Unique Gene ID

Haaura.g00004528

Gene Model ID

Haaura.CG.MTP2014.S355.g04528

Location

S355:24680..50127

Transcript Models and Sequences

  Haaura.CG.MTP2014.S355.g04528.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
USP_CS ProSitePatterns Ubiquitin specific protease, conserved site
USP_dom ProSiteProfiles Ubiquitin specific protease domain
Peptidase_C19_UCH Pfam Peptidase C19, ubiquitin carboxyl-terminal hydrolase

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
thiol-dependent ubiquitin-specific protease activity Hs molecular function
protein binding Hs molecular function
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
DNA repair Hs biological process
base-excision repair Hs biological process
proteolysis Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
peptidase activity Hs molecular function
cysteine-type peptidase activity Hs molecular function
negative regulation of G2/M transition of mitotic cell cycle Hs biological process
protein deubiquitination Hs biological process
hydrolase activity Hs molecular function
SCF ubiquitin ligase complex Hs cellular component
positive regulation of cell growth Hs biological process
cellular response to UV Hs biological process
thiol-dependent ubiquitinyl hydrolase activity Hs molecular function
response to drug Hs biological process
negative regulation of apoptotic process Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
WD40-repeat domain binding Hs molecular function
positive regulation of canonical Wnt signaling pathway Hs biological process
ubiquitinyl hydrolase activity Hs molecular function
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
p53 binding Hs molecular function 188 3.87e-48
cysteine-type endopeptidase activity Hs molecular function 188 3.87e-48
thiol-dependent ubiquitin-specific protease activity Hs molecular function 673 0.0
protein binding Hs molecular function 673 0.0
nucleus Hs cellular component 188 3.87e-48
nucleoplasm Hs cellular component 673 0.0
chromosome Hs cellular component 188 3.87e-48
cytoplasm Hs cellular component 673 0.0
cytosol Hs cellular component 188 3.87e-48
protein C-terminus binding Hs molecular function 188 3.87e-48
transcription factor binding Hs molecular function 188 3.87e-48
peptidase activity Hs molecular function 673 0.0
cysteine-type peptidase activity Hs molecular function 673 0.0
nuclear body Hs cellular component 188 3.87e-48
PML body Hs cellular component 188 3.87e-48
hydrolase activity Hs molecular function 673 0.0
SCF ubiquitin ligase complex Hs cellular component 673 0.0
ubiquitin protein ligase binding Hs molecular function 188 3.87e-48
macromolecular complex Hs cellular component 188 3.87e-48
thiol-dependent ubiquitinyl hydrolase activity Hs molecular function 673 0.0
WD40-repeat domain binding Hs molecular function 673 0.0
ubiquitinyl hydrolase activity Hs molecular function 673 0.0
Lys48-specific deubiquitinase activity Hs molecular function 188 3.87e-48

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ubiquitin-dependent protein catabolic process ProSitePatterns biological process
protein deubiquitination Pfam biological process 1.1E-47
thiol-dependent ubiquitinyl hydrolase activity Pfam molecular function 1.1E-47

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