Gene Card
Best human hits
ANKFY1; HGS; TOM1
Species
Unique Gene ID
Haaura.g00004145
Gene Model ID
Haaura.CG.MTP2014.S302.g04145
Location
S302:41001..48448
Transcript Models and Sequences
Haaura.CG.MTP2014.S302.g04145.01.t
Haaura.CG.MTP2014.S302.g04145.02.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
13 results
| IPR Term | Analysis | Definition |
|---|---|---|
| ENTH_VHS | Gene3D | ENTH/VHS |
| HRS_helical | Pfam | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain |
| Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
| Ubi-bd_Hrs_VPS27 | PIRSF | Ubiquitin binding protein, Hrs/VPS27 |
| VHS_dom | SMART | VHS domain |
| Znf_FYVE | SMART | FYVE zinc finger |
| Znf_FYVE_PHD | SUPERFAMILY | Zinc finger, FYVE/PHD-type |
| VHS_dom | ProSiteProfiles | VHS domain |
| UIM_dom | ProSiteProfiles | Ubiquitin interacting motif |
| ENTH_VHS | SUPERFAMILY | ENTH/VHS |
| VHS_dom | Pfam | VHS domain |
| Znf_FYVE-rel | ProSiteProfiles | Zinc finger, FYVE-related |
| Znf_FYVE | Pfam | FYVE zinc finger |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
36 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| protein binding | Hs | molecular function |
| intracellular | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| lysosome | Hs | cellular component |
| endosome | Hs | cellular component |
| early endosome | Hs | cellular component |
| cytosol | Hs | cellular component |
| protein targeting to lysosome | Hs | biological process |
| intracellular protein transport | Hs | biological process |
| signal transduction | Hs | biological process |
| negative regulation of cell proliferation | Hs | biological process |
| positive regulation of gene expression | Hs | biological process |
| protein transport | Hs | biological process |
| membrane | Hs | cellular component |
| endosomal transport | Hs | biological process |
| macroautophagy | Hs | biological process |
| kinase activity | Hs | molecular function |
| phosphorylation | Hs | biological process |
| negative regulation of angiogenesis | Hs | biological process |
| protein deubiquitination | Hs | biological process |
| protein domain specific binding | Hs | molecular function |
| negative regulation of vascular endothelial growth factor receptor signaling pathway | Hs | biological process |
| early endosome membrane | Hs | cellular component |
| multivesicular body membrane | Hs | cellular component |
| ESCRT-0 complex | Hs | cellular component |
| multivesicular body assembly | Hs | biological process |
| negative regulation of epidermal growth factor receptor signaling pathway | Hs | biological process |
| regulation of protein catabolic process | Hs | biological process |
| intracellular membrane-bounded organelle | Hs | cellular component |
| regulation of MAP kinase activity | Hs | biological process |
| ubiquitin-like protein ligase binding | Hs | molecular function |
| negative regulation of JAK-STAT cascade | Hs | biological process |
| metal ion binding | Hs | molecular function |
| membrane organization | Hs | biological process |
| extracellular exosome | Hs | cellular component |
| protein localization to membrane | Hs | biological process |
GO (Blast)
27 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| protein binding | Hs | molecular function | 565 | 0.0 |
| intracellular | Hs | cellular component | 565 | 0.0 |
| cytoplasm | Hs | cellular component | 565 | 0.0 |
| lysosome | Hs | cellular component | 565 | 0.0 |
| lysosomal membrane | Hs | cellular component | 82.8 | 4.64e-16 |
| endosome | Hs | cellular component | 565 | 0.0 |
| early endosome | Hs | cellular component | 565 | 0.0 |
| cytosol | Hs | cellular component | 565 | 0.0 |
| plasma membrane | Hs | cellular component | 78.6 | 4.38e-15 |
| endosome membrane | Hs | cellular component | 82.8 | 4.64e-16 |
| membrane | Hs | cellular component | 565 | 0.0 |
| kinase activity | Hs | molecular function | 565 | 0.0 |
| Rab GTPase binding | Hs | molecular function | 82.8 | 4.64e-16 |
| protein domain specific binding | Hs | molecular function | 565 | 0.0 |
| clathrin binding | Hs | molecular function | 78.6 | 4.38e-15 |
| retromer complex | Hs | cellular component | 82.8 | 4.64e-16 |
| early endosome membrane | Hs | cellular component | 565 | 0.0 |
| multivesicular body membrane | Hs | cellular component | 565 | 0.0 |
| ESCRT-0 complex | Hs | cellular component | 565 | 0.0 |
| azurophil granule membrane | Hs | cellular component | 78.6 | 4.38e-15 |
| specific granule membrane | Hs | cellular component | 78.6 | 4.38e-15 |
| intracellular membrane-bounded organelle | Hs | cellular component | 565 | 0.0 |
| macropinosome | Hs | cellular component | 82.8 | 4.64e-16 |
| ubiquitin-like protein ligase binding | Hs | molecular function | 565 | 0.0 |
| metal ion binding | Hs | molecular function | 565 | 0.0 |
| extracellular exosome | Hs | cellular component | 565 | 0.0 |
| phosphatidylinositol phosphate binding | Hs | molecular function | 82.8 | 4.64e-16 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| intracellular protein transport | Pfam | biological process | 3.5E-33 |
| metal ion binding | Pfam | molecular function | 3.8E-12 |
