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GENE CARD

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Gene Card

Best human hits

ACVR1B; ACVR1C; TGFBR1

Species

H.aurantium

Unique Gene ID

Haaura.g00002288

Gene Model ID

Haaura.CG.MTP2014.S118.g02288

Location

S118:87329..91949

Transcript Models and Sequences

  Haaura.CG.MTP2014.S118.g02288.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Activin_recp Pfam Activin types I and II receptor domain
GS_dom ProSiteProfiles GS domain
Prot_kinase_dom SMART Protein kinase domain
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
GS_dom Pfam GS domain
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
TGFB_receptor PANTHER Ser/Thr protein kinase, TGFB receptor
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
GS_dom SMART GS domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

124 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
G1/S transition of mitotic cell cycle Hs biological process
nucleotide binding Hs molecular function
activation of MAPKK activity Hs biological process
skeletal system development Hs biological process
angiogenesis Hs biological process
kidney development Hs biological process
epithelial to mesenchymal transition Hs biological process
positive regulation of endothelial cell proliferation Hs biological process
response to dietary excess Hs biological process
lens development in camera-type eye Hs biological process
ventricular trabecula myocardium morphogenesis Hs biological process
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
transmembrane receptor protein serine/threonine kinase activity Hs molecular function
signal transducer, downstream of receptor, with serine/threonine kinase activity Hs molecular function
transforming growth factor beta-activated receptor activity Hs molecular function
transforming growth factor beta receptor activity, type I Hs molecular function
signal transducer activity, downstream of receptor Hs molecular function
receptor binding Hs molecular function
type II transforming growth factor beta receptor binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
cell Hs cellular component
endosome Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
bicellular tight junction Hs cellular component
regulation of transcription, DNA-templated Hs biological process
protein phosphorylation Hs biological process
apoptotic process Hs biological process
cell cycle arrest Hs biological process
signal transduction Hs biological process
transmembrane receptor protein serine/threonine kinase signaling pathway Hs biological process
transforming growth factor beta receptor signaling pathway Hs biological process
central nervous system development Hs biological process
heart development Hs biological process
positive regulation of cell proliferation Hs biological process
germ cell migration Hs biological process
male gonad development Hs biological process
response to glucose Hs biological process
post-embryonic development Hs biological process
anterior/posterior pattern specification Hs biological process
regulation of signal transduction Hs biological process
cell surface Hs cellular component
regulation of gene expression Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
regulation of epithelial to mesenchymal transition Hs biological process
positive regulation of epithelial to mesenchymal transition Hs biological process
positive regulation of pathway-restricted SMAD protein phosphorylation Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
activin receptor activity, type I Hs molecular function
protein deubiquitination Hs biological process
transferase activity Hs molecular function
activin-activated receptor activity Hs molecular function
peptidyl-serine phosphorylation Hs biological process
peptidyl-threonine phosphorylation Hs biological process
growth factor binding Hs molecular function
lipid storage Hs biological process
signal transduction by protein phosphorylation Hs biological process
cell junction Hs cellular component
cell differentiation Hs biological process
collagen fibril organization Hs biological process
positive regulation of cell growth Hs biological process
negative regulation of cell growth Hs biological process
positive regulation of cell migration Hs biological process
negative regulation of transforming growth factor beta receptor signaling pathway Hs biological process
regulation of protein ubiquitination Hs biological process
ubiquitin protein ligase binding Hs molecular function
response to insulin Hs biological process
activin receptor signaling pathway Hs biological process
positive regulation of activin receptor signaling pathway Hs biological process
inhibin binding Hs molecular function
intracellular signal transduction Hs biological process
nodal signaling pathway Hs biological process
nodal binding Hs molecular function
regulation of growth Hs biological process
wound healing Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
intracellular membrane-bounded organelle Hs cellular component
receptor complex Hs cellular component
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
regulation of protein binding Hs biological process
endothelial cell migration Hs biological process
membrane raft Hs cellular component
positive regulation of erythrocyte differentiation Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
SMAD binding Hs molecular function
development of primary female sexual characteristics Hs biological process
negative regulation of insulin secretion Hs biological process
protein autophosphorylation Hs biological process
metal ion binding Hs molecular function
activin receptor complex Hs cellular component
activin binding Hs molecular function
thymus development Hs biological process
neuron fate commitment Hs biological process
embryonic cranial skeleton morphogenesis Hs biological process
skeletal system morphogenesis Hs biological process
artery morphogenesis Hs biological process
cell motility Hs biological process
transforming growth factor beta binding Hs molecular function
positive regulation of filopodium assembly Hs biological process
positive regulation of stress fiber assembly Hs biological process
positive regulation of protein kinase B signaling Hs biological process
parathyroid gland development Hs biological process
palate development Hs biological process
pharyngeal system development Hs biological process
regulation of cardiac muscle cell proliferation Hs biological process
pathway-restricted SMAD protein phosphorylation Hs biological process
angiogenesis involved in coronary vascular morphogenesis Hs biological process
transforming growth factor beta receptor complex Hs cellular component
extracellular exosome Hs cellular component
I-SMAD binding Hs molecular function
cellular response to transforming growth factor beta stimulus Hs biological process
extrinsic apoptotic signaling pathway Hs biological process
positive regulation of trophoblast cell migration Hs biological process
positive regulation of apoptotic signaling pathway Hs biological process
negative regulation of extrinsic apoptotic signaling pathway Hs biological process

GO (Blast)

41 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 496 1.69e-172
protein kinase activity Hs molecular function 496 1.69e-172
protein serine/threonine kinase activity Hs molecular function 496 1.69e-172
transmembrane receptor protein serine/threonine kinase activity Hs molecular function 496 1.69e-172
signal transducer, downstream of receptor, with serine/threonine kinase activity Hs molecular function 496 1.69e-172
transforming growth factor beta-activated receptor activity Hs molecular function 496 1.69e-172
transforming growth factor beta receptor activity, type I Hs molecular function 496 1.69e-172
signal transducer activity, downstream of receptor Hs molecular function 496 1.69e-172
receptor binding Hs molecular function 496 1.69e-172
type II transforming growth factor beta receptor binding Hs molecular function 496 1.69e-172
protein binding Hs molecular function 496 1.69e-172
ATP binding Hs molecular function 496 1.69e-172
cell Hs cellular component 496 1.69e-172
endosome Hs cellular component 496 1.69e-172
cytosol Hs cellular component 443 2.96e-151
plasma membrane Hs cellular component 496 1.69e-172
integral component of plasma membrane Hs cellular component 443 2.96e-151
bicellular tight junction Hs cellular component 496 1.69e-172
cell surface Hs cellular component 496 1.69e-172
membrane Hs cellular component 496 1.69e-172
integral component of membrane Hs cellular component 496 1.69e-172
kinase activity Hs molecular function 496 1.69e-172
activin receptor activity, type I Hs molecular function 447 7.91e-154
transferase activity Hs molecular function 496 1.69e-172
activin-activated receptor activity Hs molecular function 443 2.96e-151
growth factor binding Hs molecular function 496 1.69e-172
cell junction Hs cellular component 496 1.69e-172
ubiquitin protein ligase binding Hs molecular function 443 2.96e-151
inhibin binding Hs molecular function 443 2.96e-151
nodal binding Hs molecular function 447 7.91e-154
intracellular membrane-bounded organelle Hs cellular component 496 1.69e-172
receptor complex Hs cellular component 496 1.69e-172
membrane raft Hs cellular component 496 1.69e-172
SMAD binding Hs molecular function 496 1.69e-172
metal ion binding Hs molecular function 496 1.69e-172
activin receptor complex Hs cellular component 447 7.91e-154
activin binding Hs molecular function 443 2.96e-151
transforming growth factor beta binding Hs molecular function 496 1.69e-172
transforming growth factor beta receptor complex Hs cellular component 496 1.69e-172
extracellular exosome Hs cellular component 443 2.96e-151
I-SMAD binding Hs molecular function 496 1.69e-172

GO (InterProScan)

6 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 3.9E-35
signal transducer, downstream of receptor, with serine/threonine kinase activity PANTHER molecular function 3.5E-175
ATP binding PANTHER molecular function 3.5E-175
protein phosphorylation Pfam biological process 3.9E-35
transmembrane receptor protein serine/threonine kinase signaling pathway PANTHER biological process 3.5E-175
membrane PANTHER cellular component 3.5E-175