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GENE CARD

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Gene Card

Best human hits

PLCB1; PLCB3; PLCB4

Species

H.aurantium

Unique Gene ID

Haaura.g00007719

Gene Model ID

Haaura.CG.MTP2014.S1143.g07719

Location

S1143:4001..21929

Transcript Models and Sequences

  Haaura.CG.MTP2014.S1143.g07719.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

16 results

IPR Term Analysis Definition
PLC_EF-hand-like Pfam Phosphoinositide-specific phospholipase C, EF-hand-like domain
PLipase_C_Pinositol-sp_Y SMART Phospholipase C, phosphatidylinositol-specific, Y domain
PI-PLC_fam PANTHER Phosphoinositide phospholipase C family
PLipase_C_Pinositol-sp_Y Pfam Phospholipase C, phosphatidylinositol-specific, Y domain
C2_dom ProSiteProfiles C2 domain
PLC-like_Pdiesterase_TIM-brl SUPERFAMILY PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
PLipase_C_PInositol-sp_X_dom ProSiteProfiles Phosphatidylinositol-specific phospholipase C, X domain
PLipase_C_PInositol-sp_X_dom SMART Phosphatidylinositol-specific phospholipase C, X domain
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
PLC-beta PIRSF Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
PLipase_C_PInositol-sp_X_dom Pfam Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC_fam PRINTS Phosphoinositide phospholipase C family
PLC-like_Pdiesterase_TIM-brl Gene3D PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
C2_domain_sf Gene3D C2 domain superfamily
C2_dom SMART C2 domain
PLipase_C_Pinositol-sp_Y ProSiteProfiles Phospholipase C, phosphatidylinositol-specific, Y domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

57 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
G2/M transition of mitotic cell cycle Hs biological process
nuclear chromatin Hs cellular component
phosphatidylinositol phospholipase C activity Hs molecular function
phospholipase C activity Hs molecular function
signal transducer activity Hs molecular function
GTPase activator activity Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
calmodulin binding Hs molecular function
lamin binding Hs molecular function
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
lipid metabolic process Hs biological process
signal transduction Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
G-protein coupled acetylcholine receptor signaling pathway Hs biological process
Wnt signaling pathway, calcium modulating pathway Hs biological process
brain development Hs biological process
memory Hs biological process
phosphoric diester hydrolase activity Hs molecular function
regulation of G-protein coupled receptor protein signaling pathway Hs biological process
membrane Hs cellular component
lipid catabolic process Hs biological process
nuclear speck Hs cellular component
hydrolase activity Hs molecular function
enzyme binding Hs molecular function
cerebral cortex development Hs biological process
nuclear membrane Hs cellular component
macromolecular complex Hs cellular component
intracellular signal transduction Hs biological process
positive regulation of embryonic development Hs biological process
protein homodimerization activity Hs molecular function
myelin sheath Hs cellular component
positive regulation of GTPase activity Hs biological process
cadherin binding Hs molecular function
fat cell differentiation Hs biological process
positive regulation of myoblast differentiation Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of JNK cascade Hs biological process
phosphatidylinositol metabolic process Hs biological process
insulin-like growth factor receptor signaling pathway Hs biological process
positive regulation of developmental growth Hs biological process
regulation of cell cycle Hs biological process
extracellular exosome Hs cellular component
interleukin-1-mediated signaling pathway Hs biological process
regulation of fertilization Hs biological process
positive regulation of G1/S transition of mitotic cell cycle Hs biological process
positive regulation of acrosome reaction Hs biological process
phospholipid metabolic process Hs biological process
activation of phospholipase C activity Hs biological process
metal ion binding Hs molecular function
sensory perception of bitter taste Hs biological process

GO (Blast)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nuclear chromatin Hs cellular component 397 2.34e-120
phosphatidylinositol phospholipase C activity Hs molecular function 397 2.34e-120
phospholipase C activity Hs molecular function 397 2.34e-120
signal transducer activity Hs molecular function 397 2.34e-120
GTPase activator activity Hs molecular function 397 2.34e-120
calcium ion binding Hs molecular function 397 2.34e-120
protein binding Hs molecular function 397 2.34e-120
calmodulin binding Hs molecular function 397 2.34e-120
lamin binding Hs molecular function 397 2.34e-120
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function 397 2.34e-120
intracellular Hs cellular component 362 5.57e-108
nucleus Hs cellular component 397 2.34e-120
nucleoplasm Hs cellular component 365 1.74e-108
cytoplasm Hs cellular component 397 2.34e-120
smooth endoplasmic reticulum Hs cellular component 362 5.57e-108
cytosol Hs cellular component 397 2.34e-120
phosphoric diester hydrolase activity Hs molecular function 397 2.34e-120
postsynaptic density Hs cellular component 362 5.57e-108
membrane Hs cellular component 397 2.34e-120
nuclear speck Hs cellular component 397 2.34e-120
hydrolase activity Hs molecular function 397 2.34e-120
enzyme binding Hs molecular function 397 2.34e-120
dendrite Hs cellular component 362 5.57e-108
nuclear membrane Hs cellular component 397 2.34e-120
macromolecular complex Hs cellular component 365 1.74e-108
protein homodimerization activity Hs molecular function 397 2.34e-120
myelin sheath Hs cellular component 397 2.34e-120
cadherin binding Hs molecular function 365 1.74e-108
extracellular exosome Hs cellular component 397 2.34e-120

GO (InterProScan)

6 results

GO Term Analysis Type e-value
phosphatidylinositol phospholipase C activity PIRSF molecular function 6.1E-158
calcium ion binding PIRSF molecular function 6.1E-158
lipid metabolic process SUPERFAMILY biological process 9.68E-126
signal transduction SMART biological process 5.4E-67
phosphoric diester hydrolase activity SUPERFAMILY molecular function 9.68E-126
intracellular signal transduction PANTHER biological process 3.2E-275

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