Aniseed - Gene card

Gene Card

Best human hits

ERN2; PINK1; STK35

Species

H.aurantium

Unique Gene ID

Haaura.g00007378

Gene Model ID

Haaura.CG.MTP2014.S1006.g07378

Location

S1006:26669..29937

Transcript Models and Sequences

Haaura.CG.MTP2014.S1006.g07378.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term	Analysis	Definition
Prot_kinase_dom	SMART	Protein kinase domain
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily
Ser/Thr_kinase_AS	ProSitePatterns	Serine/threonine-protein kinase, active site
Prot_kinase_dom	Pfam	Protein kinase domain
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

90 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
ubiquitin ligase complex	Hs	cellular component
nucleotide binding	Hs	molecular function
magnesium ion binding	Hs	molecular function
autophagy of mitochondrion	Hs	biological process
chromatin	Hs	cellular component
positive regulation of protein phosphorylation	Hs	biological process
protease binding	Hs	molecular function
regulation of oxidative phosphorylation	Hs	biological process
response to ischemia	Hs	biological process
protein kinase activity	Hs	molecular function
protein serine/threonine kinase activity	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
mitochondrial outer membrane	Hs	cellular component
mitochondrial outer membrane translocase complex	Hs	cellular component
mitochondrial inner membrane	Hs	cellular component
mitochondrial intermembrane space	Hs	cellular component
cytosol	Hs	cellular component
cytoskeleton	Hs	cellular component
protein phosphorylation	Hs	biological process
ubiquitin-dependent protein catabolic process	Hs	biological process
autophagy	Hs	biological process
response to oxidative stress	Hs	biological process
mitochondrion organization	Hs	biological process
regulation of hydrogen peroxide metabolic process	Hs	biological process
negative regulation of gene expression	Hs	biological process
regulation of mitochondrion organization	Hs	biological process
calcium-dependent protein kinase activity	Hs	molecular function
positive regulation of peptidase activity	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
macroautophagy	Hs	biological process
positive regulation of macroautophagy	Hs	biological process
negative regulation of macroautophagy	Hs	biological process
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
peptidase activator activity	Hs	molecular function
protein ubiquitination	Hs	biological process
transferase activity	Hs	molecular function
peptidyl-serine phosphorylation	Hs	biological process
respiratory electron transport chain	Hs	biological process
axon	Hs	cellular component
growth cone	Hs	cellular component
integral component of mitochondrial outer membrane	Hs	cellular component
regulation of protein ubiquitination	Hs	biological process
positive regulation of protein ubiquitination	Hs	biological process
ubiquitin protein ligase binding	Hs	molecular function
TORC2 complex	Hs	cellular component
positive regulation of synaptic transmission, dopaminergic	Hs	biological process
positive regulation of peptidyl-serine phosphorylation	Hs	biological process
cellular response to oxidative stress	Hs	biological process
positive regulation of protein dephosphorylation	Hs	biological process
intracellular signal transduction	Hs	biological process
TORC2 signaling	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
protein kinase B binding	Hs	molecular function
regulation of neuron apoptotic process	Hs	biological process
negative regulation of neuron apoptotic process	Hs	biological process
cell body	Hs	cellular component
positive regulation of translation	Hs	biological process
negative regulation of JNK cascade	Hs	biological process
metal ion binding	Hs	molecular function
perinuclear region of cytoplasm	Hs	cellular component
protein stabilization	Hs	biological process
positive regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
positive regulation of ubiquitin-protein transferase activity	Hs	biological process
regulation of mitochondrial membrane potential	Hs	biological process
positive regulation of protein kinase B signaling	Hs	biological process
C3HC4-type RING finger domain binding	Hs	molecular function
regulation of proteasomal protein catabolic process	Hs	biological process
cellular response to hypoxia	Hs	biological process
positive regulation of mitochondrial fission	Hs	biological process
positive regulation of release of cytochrome c from mitochondria	Hs	biological process
cellular response to toxic substance	Hs	biological process
Lewy body	Hs	cellular component
astrocyte projection	Hs	cellular component
regulation of cellular response to oxidative stress	Hs	biological process
negative regulation of neuron death	Hs	biological process
negative regulation of autophagosome assembly	Hs	biological process
regulation of autophagy of mitochondrion	Hs	biological process
negative regulation of autophagy of mitochondrion	Hs	biological process
negative regulation of oxidative stress-induced neuron death	Hs	biological process
regulation of reactive oxygen species metabolic process	Hs	biological process
negative regulation of reactive oxygen species metabolic process	Hs	biological process
positive regulation of ATP biosynthetic process	Hs	biological process
negative regulation of intrinsic apoptotic signaling pathway	Hs	biological process

GO (Blast)

45 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
ubiquitin ligase complex	Hs	cellular component	200	1.86e-56
nucleotide binding	Hs	molecular function	200	1.86e-56
magnesium ion binding	Hs	molecular function	200	1.86e-56
chromatin	Hs	cellular component	200	1.86e-56
protease binding	Hs	molecular function	200	1.86e-56
catalytic activity	Hs	molecular function	59.3	5.51e-09
endonuclease activity	Hs	molecular function	59.3	5.51e-09
ribonuclease activity	Hs	molecular function	59.3	5.51e-09
protein kinase activity	Hs	molecular function	200	1.86e-56
protein serine/threonine kinase activity	Hs	molecular function	200	1.86e-56
protein binding	Hs	molecular function	200	1.86e-56
ATP binding	Hs	molecular function	200	1.86e-56
nucleus	Hs	cellular component	200	1.86e-56
nucleolus	Hs	cellular component	55.5	6.90e-08
cytoplasm	Hs	cellular component	200	1.86e-56
mitochondrion	Hs	cellular component	200	1.86e-56
mitochondrial outer membrane	Hs	cellular component	200	1.86e-56
mitochondrial outer membrane translocase complex	Hs	cellular component	200	1.86e-56
mitochondrial inner membrane	Hs	cellular component	200	1.86e-56
mitochondrial intermembrane space	Hs	cellular component	200	1.86e-56
endoplasmic reticulum	Hs	cellular component	59.3	5.51e-09
endoplasmic reticulum membrane	Hs	cellular component	59.3	5.51e-09
cytosol	Hs	cellular component	200	1.86e-56
cytoskeleton	Hs	cellular component	200	1.86e-56
calcium-dependent protein kinase activity	Hs	molecular function	200	1.86e-56
membrane	Hs	cellular component	200	1.86e-56
integral component of membrane	Hs	cellular component	200	1.86e-56
kinase activity	Hs	molecular function	200	1.86e-56
peptidase activator activity	Hs	molecular function	200	1.86e-56
nuclear body	Hs	cellular component	55.5	6.90e-08
transferase activity	Hs	molecular function	200	1.86e-56
hydrolase activity	Hs	molecular function	59.3	5.51e-09
axon	Hs	cellular component	200	1.86e-56
growth cone	Hs	cellular component	200	1.86e-56
integral component of mitochondrial outer membrane	Hs	cellular component	200	1.86e-56
ubiquitin protein ligase binding	Hs	molecular function	200	1.86e-56
TORC2 complex	Hs	cellular component	200	1.86e-56
protein kinase B binding	Hs	molecular function	200	1.86e-56
cell body	Hs	cellular component	200	1.86e-56
metal ion binding	Hs	molecular function	200	1.86e-56
perinuclear region of cytoplasm	Hs	cellular component	200	1.86e-56
C3HC4-type RING finger domain binding	Hs	molecular function	200	1.86e-56
Lewy body	Hs	cellular component	200	1.86e-56
astrocyte projection	Hs	cellular component	200	1.86e-56
IRE1-TRAF2-ASK1 complex	Hs	cellular component	59.3	5.51e-09

GO (InterProScan)

3 results

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	5.1E-18
ATP binding	Pfam	molecular function	5.1E-18
protein phosphorylation	Pfam	biological process	5.1E-18