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GENE CARD

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Gene Card

Best human hits

SHMT1; SHMT2

Species

C.savignyi

Unique Gene ID

Cisavi.g00010196

Gene Model ID

Cisavi.CG.ENS81.R7.2308031-2312975

Location

R7:2308030..2312975

Transcript Models and Sequences

  Cisavi.CG.ENS81.R7.2308031-2312975.11965.t
Cisavi.CG.ENS81.R7.2308031-2312975.11966.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Ser_HO-MeTrfase_PLP_BS ProSitePatterns Serine hydroxymethyltransferase, pyridoxal phosphate binding site
PyrdxlP-dep_Trfase_major Gene3D Pyridoxal phosphate-dependent transferase, major domain
Ser_HO-MeTrfase Hamap Serine hydroxymethyltransferase
Ser_HO-MeTrfase CDD Serine hydroxymethyltransferase
PyrdxlP-dep_Trfase SUPERFAMILY Pyridoxal phosphate-dependent transferase
Ser_HO-MeTrfase PIRSF Serine hydroxymethyltransferase
PyrdxlP-dep_Trfase_dom1 Gene3D Pyridoxal phosphate-dependent transferase domain 1

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
translation repressor activity, nucleic acid binding Hs molecular function
catalytic activity Hs molecular function
glycine hydroxymethyltransferase activity Hs molecular function
thiol-dependent ubiquitin-specific protease activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
dTMP biosynthetic process Hs biological process
glycine metabolic process Hs biological process
glycine biosynthetic process Hs biological process
L-serine metabolic process Hs biological process
one-carbon metabolic process Hs biological process
L-allo-threonine aldolase activity Hs molecular function
purine nucleobase biosynthetic process Hs biological process
protein deubiquitination Hs biological process
amino acid binding Hs molecular function
transferase activity Hs molecular function
negative regulation of translation Hs biological process
glycine biosynthetic process from serine Hs biological process
pyridoxal phosphate binding Hs molecular function
tetrahydrofolate interconversion Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
carnitine biosynthetic process Hs biological process
tetrahydrofolate metabolic process Hs biological process
folic acid metabolic process Hs biological process
mRNA 5'-UTR binding Hs molecular function
protein tetramerization Hs biological process
protein homotetramerization Hs biological process
extracellular exosome Hs cellular component
serine binding Hs molecular function

GO (Blast)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
translation repressor activity, nucleic acid binding Hs molecular function 616 0.0
chromatin binding Hs molecular function 579 0.0
catalytic activity Hs molecular function 616 0.0
glycine hydroxymethyltransferase activity Hs molecular function 616 0.0
thiol-dependent ubiquitin-specific protease activity Hs molecular function 616 0.0
protein binding Hs molecular function 616 0.0
nucleus Hs cellular component 616 0.0
cytoplasm Hs cellular component 616 0.0
mitochondrion Hs cellular component 616 0.0
mitochondrial inner membrane Hs cellular component 579 0.0
mitochondrial intermembrane space Hs cellular component 579 0.0
mitochondrial matrix Hs cellular component 579 0.0
cytosol Hs cellular component 616 0.0
methyltransferase activity Hs molecular function 579 0.0
L-allo-threonine aldolase activity Hs molecular function 616 0.0
microtubule cytoskeleton Hs cellular component 579 0.0
membrane Hs cellular component 579 0.0
amino acid binding Hs molecular function 616 0.0
transferase activity Hs molecular function 616 0.0
pyridoxal phosphate binding Hs molecular function 616 0.0
mitochondrial nucleoid Hs cellular component 579 0.0
identical protein binding Hs molecular function 616 0.0
protein homodimerization activity Hs molecular function 616 0.0
mRNA 5'-UTR binding Hs molecular function 616 0.0
extracellular exosome Hs cellular component 616 0.0
BRISC complex Hs cellular component 579 0.0
serine binding Hs molecular function 616 0.0

GO (InterProScan)

5 results

GO Term Analysis Type e-value
catalytic activity Gene3D molecular function 3.9E-197
glycine hydroxymethyltransferase activity CDD molecular function 0.0
glycine biosynthetic process from serine CDD biological process 0.0
pyridoxal phosphate binding CDD molecular function 0.0
tetrahydrofolate interconversion CDD biological process 0.0

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