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GENE CARD

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Gene Card

Best human hits

MYC; MYCL; MYCN

Species

C.savignyi

Unique Gene ID

Cisavi.g00008638

Gene Model ID

Cisavi.CG.ENS81.R5.239883-255452

Location

R5:239882..255452

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
Tscrpt_reg_Myc PRINTS Transcription regulator Myc
Tscrpt_reg_Myc_N Pfam Transcription regulator Myc, N-terminal
bHLH_dom Pfam Myc-type, basic helix-loop-helix (bHLH) domain
bHLH_dom ProSiteProfiles Myc-type, basic helix-loop-helix (bHLH) domain
HLH_DNA-bd_sf SUPERFAMILY Helix-loop-helix DNA-binding domain superfamily
bHLH_dom SMART Myc-type, basic helix-loop-helix (bHLH) domain
bHLH_dom CDD Myc-type, basic helix-loop-helix (bHLH) domain
HLH_DNA-bd_sf Gene3D Helix-loop-helix DNA-binding domain superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

103 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
G1/S transition of mitotic cell cycle Hs biological process
negative regulation of transcription from RNA polymerase II promoter Hs biological process
MAPK cascade Hs biological process
chromatin Hs cellular component
nuclear chromatin Hs cellular component
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
cartilage condensation Hs biological process
ovarian follicle development Hs biological process
branching involved in ureteric bud morphogenesis Hs biological process
regulation of oxidative phosphorylation Hs biological process
DNA binding Hs molecular function
double-stranded DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
mRNA binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nuclear envelope Hs cellular component
nucleoplasm Hs cellular component
nucleolus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
rough endoplasmic reticulum Hs cellular component
cytosol Hs cellular component
glucose metabolic process Hs biological process
energy reserve metabolic process Hs biological process
chromatin remodeling Hs biological process
transcription, DNA-templated Hs biological process
DNA-templated transcription, initiation Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
amino acid transport Hs biological process
cellular iron ion homeostasis Hs biological process
cellular response to DNA damage stimulus Hs biological process
inner mitochondrial membrane organization Hs biological process
cell cycle arrest Hs biological process
Notch signaling pathway Hs biological process
regulation of mitotic cell cycle Hs biological process
transcription factor binding Hs molecular function
cell proliferation Hs biological process
positive regulation of cell proliferation Hs biological process
response to wounding Hs biological process
response to gamma radiation Hs biological process
regulation of gene expression Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
positive regulation of mitochondrial membrane potential Hs biological process
positive regulation of cell death Hs biological process
oxygen transport Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
protein deubiquitination Hs biological process
cytokine-mediated signaling pathway Hs biological process
kinase binding Hs molecular function
hypothalamus development Hs biological process
lung development Hs biological process
ovulation Hs biological process
response to estradiol Hs biological process
cellular response to insulin stimulus Hs biological process
negative regulation of stress-activated MAPK cascade Hs biological process
macromolecular complex Hs cellular component
activating transcription factor binding Hs molecular function
cellular response to UV Hs biological process
response to drug Hs biological process
negative regulation of apoptotic process Hs biological process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
positive regulation of DNA binding Hs biological process
sequence-specific DNA binding Hs molecular function
nucleoplasmic reticulum Hs cellular component
macromolecular complex binding Hs molecular function
response to ethanol Hs biological process
positive regulation of translation Hs biological process
positive regulation of cell cycle Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
protein heterodimerization activity Hs molecular function
protein dimerization activity Hs molecular function
branching morphogenesis of an epithelial tube Hs biological process
positive regulation of epithelial cell proliferation Hs biological process
chromosome organization Hs biological process
negative regulation of cell division Hs biological process
canonical Wnt signaling pathway Hs biological process
positive regulation of glial cell proliferation Hs biological process
negative regulation of cell death Hs biological process
repressing transcription factor binding Hs molecular function
response to growth factor Hs biological process
E-box binding Hs molecular function
eukaryotic initiation factor eIF2 binding Hs molecular function
cellular response to retinoic acid Hs biological process
cellular response to carbohydrate stimulus Hs biological process
cellular response to interferon-gamma Hs biological process
cellular response to interleukin-1 Hs biological process
cellular response to epidermal growth factor stimulus Hs biological process
cellular response to estrogen stimulus Hs biological process
cellular response to organic cyclic compound Hs biological process
cellular response to hypoxia Hs biological process
positive regulation of cellular respiration Hs biological process
positive regulation of oxidative phosphorylation Hs biological process
negative regulation of reactive oxygen species metabolic process Hs biological process
positive regulation of response to DNA damage stimulus Hs biological process
positive regulation of ATP biosynthetic process Hs biological process

GO (Blast)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
chromatin Hs cellular component 75.9 2.07e-14
nuclear chromatin Hs cellular component 73.2 1.45e-13
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 75.9 2.07e-14
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 75.9 2.07e-14
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 75.9 2.07e-14
DNA binding Hs molecular function 75.9 2.07e-14
double-stranded DNA binding Hs molecular function 73.2 1.45e-13
transcription factor activity, sequence-specific DNA binding Hs molecular function 75.9 2.07e-14
mRNA binding Hs molecular function 73.2 1.45e-13
protein binding Hs molecular function 75.9 2.07e-14
nucleus Hs cellular component 75.9 2.07e-14
nuclear envelope Hs cellular component 73.2 1.45e-13
nucleoplasm Hs cellular component 73.2 1.45e-13
nucleolus Hs cellular component 75.9 2.07e-14
cytoplasm Hs cellular component 73.2 1.45e-13
mitochondrion Hs cellular component 73.2 1.45e-13
rough endoplasmic reticulum Hs cellular component 73.2 1.45e-13
cytosol Hs cellular component 73.2 1.45e-13
transcription factor binding Hs molecular function 73.2 1.45e-13
membrane Hs cellular component 73.2 1.45e-13
integral component of membrane Hs cellular component 73.2 1.45e-13
kinase binding Hs molecular function 75.9 2.07e-14
macromolecular complex Hs cellular component 73.2 1.45e-13
activating transcription factor binding Hs molecular function 73.2 1.45e-13
sequence-specific DNA binding Hs molecular function 73.2 1.45e-13
nucleoplasmic reticulum Hs cellular component 73.2 1.45e-13
macromolecular complex binding Hs molecular function 73.2 1.45e-13
protein heterodimerization activity Hs molecular function 73.2 1.45e-13
protein dimerization activity Hs molecular function 75.9 2.07e-14
repressing transcription factor binding Hs molecular function 73.2 1.45e-13
E-box binding Hs molecular function 73.2 1.45e-13
eukaryotic initiation factor eIF2 binding Hs molecular function 73.2 1.45e-13

GO (InterProScan)

4 results

GO Term Analysis Type e-value
transcription factor activity, sequence-specific DNA binding Pfam molecular function 1.4E-16
nucleus PRINTS cellular component 6.7E-9
regulation of transcription, DNA-templated Pfam biological process 1.4E-16
protein dimerization activity Gene3D molecular function 2.3E-18