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GENE CARD

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Gene Card

Best human hits

NVL; SPATA5; VCP

Species

C.savignyi

Unique Gene ID

Cisavi.g00008035

Gene Model ID

Cisavi.CG.ENS81.R48.2152627-2164543

Location

R48:2152626..2164543

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
Asp_de-COase-like_dom_sf SUPERFAMILY Aspartate decarboxylase-like domain superfamily
Cdc48_dom2 Pfam CDC48, domain 2
ATPase_AAA_core Pfam ATPase, AAA-type, core
CDC4_N-term_subdom SMART CDC48, N-terminal subdomain
Cdc48_dom2 SMART CDC48, domain 2
AAA_ATPase_CDC48 TIGRFAM AAA ATPase, CDC48 family
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
CDC48_domain_2-like_sf SUPERFAMILY CDC48 domain 2-like superfamily
AAA+_ATPase SMART AAA+ ATPase domain
ATPase_AAA_CS ProSitePatterns ATPase, AAA-type, conserved site
Vps4_C Pfam Vps4 oligomerisation, C-terminal
CDC4_N-term_subdom Pfam CDC48, N-terminal subdomain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

81 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
proteasome complex Hs cellular component
RNA binding Hs molecular function
receptor binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
extracellular region Hs cellular component
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
endoplasmic reticulum membrane Hs cellular component
lipid droplet Hs cellular component
cytosol Hs cellular component
DNA repair Hs biological process
double-strand break repair Hs biological process
protein folding Hs biological process
protein methylation Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
NADH metabolic process Hs biological process
ER to Golgi vesicle-mediated transport Hs biological process
autophagy Hs biological process
activation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
lipid binding Hs molecular function
proteasomal protein catabolic process Hs biological process
positive regulation of mitochondrial membrane potential Hs biological process
macroautophagy Hs biological process
protein ubiquitination Hs biological process
protein deubiquitination Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
protein N-linked glycosylation via asparagine Hs biological process
viral genome replication Hs biological process
protein phosphatase binding Hs molecular function
protein domain specific binding Hs molecular function
translesion synthesis Hs biological process
ubiquitin-dependent ERAD pathway Hs biological process
endoplasmic reticulum unfolded protein response Hs biological process
retrograde protein transport, ER to cytosol Hs biological process
positive regulation of protein complex assembly Hs biological process
polyubiquitin modification-dependent protein binding Hs molecular function
ubiquitin protein ligase binding Hs molecular function
positive regulation of proteasomal ubiquitin-dependent protein catabolic process Hs biological process
endosome to lysosome transport via multivesicular body sorting pathway Hs biological process
macromolecular complex Hs cellular component
VCP-NPL4-UFD1 AAA ATPase complex Hs cellular component
protein hexamerization Hs biological process
secretory granule lumen Hs cellular component
azurophil granule lumen Hs cellular component
deubiquitinase activator activity Hs molecular function
site of double-strand break Hs cellular component
K48-linked polyubiquitin modification-dependent protein binding Hs molecular function
ERAD pathway Hs biological process
Derlin-1 retrotranslocation complex Hs cellular component
MHC class I protein binding Hs molecular function
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
myelin sheath Hs cellular component
intracellular membrane-bounded organelle Hs cellular component
ADP binding Hs molecular function
ubiquitin-like protein ligase binding Hs molecular function
establishment of protein localization Hs biological process
positive regulation of protein catabolic process Hs biological process
ATP metabolic process Hs biological process
perinuclear region of cytoplasm Hs cellular component
protein homooligomerization Hs biological process
transmembrane transport Hs biological process
extracellular exosome Hs cellular component
ER-associated misfolded protein catabolic process Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
autophagosome maturation Hs biological process
positive regulation of oxidative phosphorylation Hs biological process
BAT3 complex binding Hs molecular function
ficolin-1-rich granule lumen Hs cellular component
ATPase complex Hs cellular component
ubiquitin-specific protease binding Hs molecular function
VCP-NSFL1C complex Hs cellular component
positive regulation of ubiquitin-specific protease activity Hs biological process
positive regulation of ATP biosynthetic process Hs biological process

GO (Blast)

47 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 1342 0.0
proteasome complex Hs cellular component 1342 0.0
RNA binding Hs molecular function 1342 0.0
receptor binding Hs molecular function 1342 0.0
protein binding Hs molecular function 1342 0.0
ATP binding Hs molecular function 1342 0.0
extracellular region Hs cellular component 1342 0.0
nucleus Hs cellular component 1342 0.0
nucleoplasm Hs cellular component 1342 0.0
telomerase holoenzyme complex Hs cellular component 462 3.80e-150
nucleolus Hs cellular component 462 3.80e-150
cytoplasm Hs cellular component 1342 0.0
mitochondrion Hs cellular component 544 0.0
endoplasmic reticulum Hs cellular component 1342 0.0
endoplasmic reticulum membrane Hs cellular component 1342 0.0
lipid droplet Hs cellular component 1342 0.0
cytosol Hs cellular component 1342 0.0
lipid binding Hs molecular function 1342 0.0
membrane Hs cellular component 462 3.80e-150
hydrolase activity Hs molecular function 1342 0.0
ATPase activity Hs molecular function 1342 0.0
protein phosphatase binding Hs molecular function 1342 0.0
protein domain specific binding Hs molecular function 1342 0.0
polyubiquitin modification-dependent protein binding Hs molecular function 1342 0.0
ubiquitin protein ligase binding Hs molecular function 1342 0.0
macromolecular complex Hs cellular component 1342 0.0
VCP-NPL4-UFD1 AAA ATPase complex Hs cellular component 1342 0.0
secretory granule lumen Hs cellular component 1342 0.0
azurophil granule lumen Hs cellular component 1342 0.0
deubiquitinase activator activity Hs molecular function 1342 0.0
site of double-strand break Hs cellular component 1342 0.0
K48-linked polyubiquitin modification-dependent protein binding Hs molecular function 1342 0.0
Derlin-1 retrotranslocation complex Hs cellular component 1342 0.0
MHC class I protein binding Hs molecular function 1342 0.0
identical protein binding Hs molecular function 1342 0.0
myelin sheath Hs cellular component 1342 0.0
intracellular membrane-bounded organelle Hs cellular component 1342 0.0
ADP binding Hs molecular function 1342 0.0
ubiquitin-like protein ligase binding Hs molecular function 1342 0.0
perinuclear region of cytoplasm Hs cellular component 1342 0.0
extracellular exosome Hs cellular component 1342 0.0
BAT3 complex binding Hs molecular function 1342 0.0
ficolin-1-rich granule lumen Hs cellular component 1342 0.0
ATPase complex Hs cellular component 1342 0.0
preribosome binding Hs molecular function 462 3.80e-150
ubiquitin-specific protease binding Hs molecular function 1342 0.0
VCP-NSFL1C complex Hs cellular component 1342 0.0

GO (InterProScan)

2 results

GO Term Analysis Type e-value
ATP binding Pfam molecular function 5.8E-46
hydrolase activity TIGRFAM molecular function 8.3E-254