Gene Card
Best human hits
DBH; MOXD1; PAM
Species
Unique Gene ID
Cisavi.g00004134
Gene Model ID
Cisavi.CG.ENS81.R2.2315545-2321082
Location
R2:2315544..2321082
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
7 results
| IPR Term | Analysis | Definition |
|---|---|---|
| DOMON_domain | ProSiteProfiles | DOMON domain |
| DOMON_domain | Pfam | DOMON domain |
| PHM/PNGase_F_dom_sf | SUPERFAMILY | PHM/PNGase F domain superfamily |
| Cu2_ascorb_mOase_N_sf | Gene3D | Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily |
| DOMON_domain | SMART | DOMON domain |
| Cu2_ascorb_mOase_N | Pfam | Copper type II, ascorbate-dependent monooxygenase, N-terminal |
| Tbh/DBH | PRINTS | Tyramine beta-hydroxylase/Dopamine beta-hydroxylase |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
18 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| catalytic activity | Hs | molecular function |
| monooxygenase activity | Hs | molecular function |
| dopamine beta-monooxygenase activity | Hs | molecular function |
| copper ion binding | Hs | molecular function |
| protein binding | Hs | molecular function |
| extracellular space | Hs | cellular component |
| endoplasmic reticulum | Hs | cellular component |
| endoplasmic reticulum membrane | Hs | cellular component |
| octopamine biosynthetic process | Hs | biological process |
| membrane | Hs | cellular component |
| integral component of membrane | Hs | cellular component |
| oxidoreductase activity | Hs | molecular function |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | Hs | molecular function |
| secretory granule membrane | Hs | cellular component |
| dopamine catabolic process | Hs | biological process |
| norepinephrine biosynthetic process | Hs | biological process |
| metal ion binding | Hs | molecular function |
| oxidation-reduction process | Hs | biological process |
GO (Blast)
39 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| catalytic activity | Hs | molecular function | 145 | 3.32e-40 |
| monooxygenase activity | Hs | molecular function | 145 | 3.32e-40 |
| dopamine beta-monooxygenase activity | Hs | molecular function | 145 | 3.32e-40 |
| peptidylglycine monooxygenase activity | Hs | molecular function | 43.5 | 7.43e-05 |
| peptidylamidoglycolate lyase activity | Hs | molecular function | 43.5 | 7.43e-05 |
| copper ion binding | Hs | molecular function | 145 | 3.32e-40 |
| calcium ion binding | Hs | molecular function | 43.5 | 7.43e-05 |
| protein binding | Hs | molecular function | 145 | 3.32e-40 |
| extracellular region | Hs | cellular component | 104 | 1.83e-25 |
| extracellular space | Hs | cellular component | 145 | 3.32e-40 |
| cytoplasm | Hs | cellular component | 104 | 1.83e-25 |
| endoplasmic reticulum | Hs | cellular component | 145 | 3.32e-40 |
| endoplasmic reticulum membrane | Hs | cellular component | 145 | 3.32e-40 |
| trans-Golgi network | Hs | cellular component | 43.5 | 7.43e-05 |
| microtubule organizing center | Hs | cellular component | 104 | 1.83e-25 |
| plasma membrane | Hs | cellular component | 43.5 | 7.43e-05 |
| zinc ion binding | Hs | molecular function | 43.5 | 7.43e-05 |
| cell surface | Hs | cellular component | 43.5 | 7.43e-05 |
| membrane | Hs | cellular component | 145 | 3.32e-40 |
| integral component of membrane | Hs | cellular component | 145 | 3.32e-40 |
| oxidoreductase activity | Hs | molecular function | 145 | 3.32e-40 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | Hs | molecular function | 145 | 3.32e-40 |
| lyase activity | Hs | molecular function | 43.5 | 7.43e-05 |
| protein kinase binding | Hs | molecular function | 43.5 | 7.43e-05 |
| secretory granule | Hs | cellular component | 43.5 | 7.43e-05 |
| transport vesicle membrane | Hs | cellular component | 104 | 1.83e-25 |
| secretory granule membrane | Hs | cellular component | 145 | 3.32e-40 |
| cytoplasmic vesicle | Hs | cellular component | 104 | 1.83e-25 |
| L-ascorbic acid binding | Hs | molecular function | 104 | 1.83e-25 |
| chromaffin granule lumen | Hs | cellular component | 104 | 1.83e-25 |
| secretory granule lumen | Hs | cellular component | 104 | 1.83e-25 |
| chromaffin granule membrane | Hs | cellular component | 104 | 1.83e-25 |
| neuron projection | Hs | cellular component | 43.5 | 7.43e-05 |
| neuronal cell body | Hs | cellular component | 43.5 | 7.43e-05 |
| perikaryon | Hs | cellular component | 43.5 | 7.43e-05 |
| intracellular membrane-bounded organelle | Hs | cellular component | 104 | 1.83e-25 |
| metal ion binding | Hs | molecular function | 145 | 3.32e-40 |
| perinuclear region of cytoplasm | Hs | cellular component | 43.5 | 7.43e-05 |
| extracellular exosome | Hs | cellular component | 43.5 | 7.43e-05 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| catalytic activity | SUPERFAMILY | molecular function | 6.8E-29 |
| monooxygenase activity | Pfam | molecular function | 5.1E-38 |
| copper ion binding | Pfam | molecular function | 5.1E-38 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | Pfam | molecular function | 5.1E-38 |
| oxidation-reduction process | Pfam | biological process | 5.1E-38 |
