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Gene Card

Best human hits

CTGF; CYR61; WISP1

Species

C.savignyi

Unique Gene ID

Cisavi.g00003649

Gene Model ID

Cisavi.CG.ENS81.R19.1631247-1634693

Location

R19:1631246..1634693

Transcript Models and Sequences

  Cisavi.CG.ENS81.R19.1631247-1634693.14463.t
Cisavi.CG.ENS81.R19.1631247-1634693.14464.t
Cisavi.CG.ENS81.R19.1631247-1634693.14465.t
Cisavi.CG.ENS81.R19.1631247-1634693.14466.t
Cisavi.CG.ENS81.R19.1631247-1634693.14467.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
TSP1_rpt ProSiteProfiles Thrombospondin type-1 (TSP1) repeat
VWF_dom SMART VWFC domain
Cys_knot_C SMART Cystine knot, C-terminal
IGFBP-like ProSiteProfiles Insulin-like growth factor-binding protein, IGFBP
IGFBP-like Pfam Insulin-like growth factor-binding protein, IGFBP
TSP1_rpt_sf SUPERFAMILY Thrombospondin type-1 (TSP1) repeat superfamily
Glyco_hormone_CN Pfam Glycoprotein hormone subunit beta
Cys_knot_C ProSiteProfiles Cystine knot, C-terminal
Cys_knot_C ProSitePatterns Cystine knot, C-terminal
Growth_fac_rcpt_cys_sf SUPERFAMILY Growth factor receptor cysteine-rich domain superfamily
IGFBP-like SMART Insulin-like growth factor-binding protein, IGFBP
TSP1_rpt_sf Gene3D Thrombospondin type-1 (TSP1) repeat superfamily
VWF_dom ProSiteProfiles VWFC domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

105 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
cartilage condensation Hs biological process
ossification Hs biological process
angiogenesis Hs biological process
regulation of cell growth Hs biological process
osteoblast differentiation Hs biological process
tissue homeostasis Hs biological process
positive regulation of protein phosphorylation Hs biological process
fibronectin binding Hs molecular function
atrioventricular valve morphogenesis Hs biological process
integrin binding Hs molecular function
protein binding Hs molecular function
insulin-like growth factor binding Hs molecular function
extracellular region Hs cellular component
proteinaceous extracellular matrix Hs cellular component
extracellular space Hs cellular component
endoplasmic reticulum lumen Hs cellular component
cis-Golgi network Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
cell cortex Hs cellular component
transcription initiation from RNA polymerase II promoter Hs biological process
chemotaxis Hs biological process
cell adhesion Hs biological process
cell-matrix adhesion Hs biological process
signal transduction Hs biological process
integrin-mediated signaling pathway Hs biological process
cell-cell signaling Hs biological process
aging Hs biological process
protein C-terminus binding Hs molecular function
growth factor activity Hs molecular function
heparin binding Hs molecular function
cell proliferation Hs biological process
positive regulation of cell proliferation Hs biological process
fibroblast growth factor receptor signaling pathway Hs biological process
epidermis development Hs biological process
response to wounding Hs biological process
anatomical structure morphogenesis Hs biological process
response to glucose Hs biological process
regulation of receptor activity Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
positive regulation of cell-substrate adhesion Hs biological process
positive regulation of cell death Hs biological process
response to organic cyclic compound Hs biological process
Wnt signaling pathway Hs biological process
cell migration Hs biological process
regulation of lipid metabolic process Hs biological process
growth factor binding Hs molecular function
cell differentiation Hs biological process
extracellular matrix organization Hs biological process
lung development Hs biological process
positive regulation of cell migration Hs biological process
positive regulation of BMP signaling pathway Hs biological process
extracellular matrix Hs cellular component
regulation of chondrocyte differentiation Hs biological process
response to estradiol Hs biological process
intracellular signal transduction Hs biological process
chondrocyte proliferation Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
response to amino acid Hs biological process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
response to peptide hormone Hs biological process
post-translational protein modification Hs biological process
wound healing, spreading of cells Hs biological process
positive regulation of cell differentiation Hs biological process
positive regulation of osteoblast differentiation Hs biological process
positive regulation of protein kinase activity Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
positive regulation of JNK cascade Hs biological process
perinuclear region of cytoplasm Hs cellular component
extracellular matrix binding Hs molecular function
positive regulation of stress fiber assembly Hs biological process
negative regulation of cell death Hs biological process
positive regulation of cartilage development Hs biological process
regulation of ERK1 and ERK2 cascade Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
DNA biosynthetic process Hs biological process
reactive oxygen species metabolic process Hs biological process
cell-cell adhesion Hs biological process
positive regulation of ceramide biosynthetic process Hs biological process
chondrocyte differentiation Hs biological process
Notch binding Hs molecular function
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
gap junction Hs cellular component
regulation of gene expression Hs biological process
cell junction Hs cellular component
negative regulation of cell growth Hs biological process
axon Hs cellular component
dendrite Hs cellular component
cell adhesion mediated by integrin Hs biological process
endothelial cell chemotaxis Hs biological process
neuronal cell body Hs cellular component
intracellular membrane-bounded organelle Hs cellular component
type B pancreatic cell proliferation Hs biological process
positive regulation of Notch signaling pathway Hs biological process
negative regulation of insulin secretion Hs biological process
smooth muscle cell proliferation Hs biological process
negative regulation of inflammatory response Hs biological process
cell chemotaxis Hs biological process
hematopoietic stem cell homeostasis Hs biological process
extracellular exosome Hs cellular component
bone regeneration Hs biological process

GO (Blast)

20 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 207 4.95e-64
fibronectin binding Hs molecular function 278 6.38e-92
integrin binding Hs molecular function 278 6.38e-92
protein binding Hs molecular function 278 6.38e-92
insulin-like growth factor binding Hs molecular function 278 6.38e-92
extracellular region Hs cellular component 278 6.38e-92
proteinaceous extracellular matrix Hs cellular component 278 6.38e-92
extracellular space Hs cellular component 278 6.38e-92
endoplasmic reticulum lumen Hs cellular component 207 4.95e-64
cis-Golgi network Hs cellular component 278 6.38e-92
cytosol Hs cellular component 278 6.38e-92
plasma membrane Hs cellular component 278 6.38e-92
cell cortex Hs cellular component 278 6.38e-92
protein C-terminus binding Hs molecular function 278 6.38e-92
growth factor activity Hs molecular function 278 6.38e-92
heparin binding Hs molecular function 278 6.38e-92
growth factor binding Hs molecular function 207 4.95e-64
extracellular matrix Hs cellular component 207 4.95e-64
perinuclear region of cytoplasm Hs cellular component 278 6.38e-92
extracellular matrix binding Hs molecular function 207 4.95e-64

GO (InterProScan)

4 results

GO Term Analysis Type e-value
regulation of cell growth ProSiteProfiles biological process 13.253
protein binding SMART molecular function 1.5E-6
insulin-like growth factor binding ProSiteProfiles molecular function 13.253
extracellular region ProSiteProfiles cellular component 13.253

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