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GENE CARD

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Gene Card

Best human hits

VAV1; VAV2; VAV3

Species

C.savignyi

Unique Gene ID

Cisavi.g00001963

Gene Model ID

Cisavi.CG.ENS81.R132.683492-711253

Location

R132:683491..711253

Transcript Models and Sequences

  Cisavi.CG.ENS81.R132.683492-711253.07751.t
Cisavi.CG.ENS81.R132.683492-711253.07752.t
Cisavi.CG.ENS81.R132.683492-711253.07753.t
Cisavi.CG.ENS81.R132.683492-711253.07754.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

31 results

IPR Term Analysis Definition
CH-domain SMART Calponin homology domain
SH3_domain ProSiteProfiles SH3 domain
PE/DAG-bd CDD Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
SH2_dom_sf Gene3D SH2 domain superfamily
SH3-like_dom_sf SUPERFAMILY SH3-like domain superfamily
SH2 ProSiteProfiles SH2 domain
CH-domain ProSiteProfiles Calponin homology domain
DBL_dom_sf Gene3D Dbl homology (DH) domain superfamily
SH2_dom_sf SUPERFAMILY SH2 domain superfamily
SH3_domain Pfam SH3 domain
CH_dom_sf Gene3D CH domain superfamily
PH-like_dom_sf Gene3D PH-like domain superfamily
PE/DAG-bd SMART Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
DH-domain CDD Dbl homology (DH) domain
CH-domain CDD Calponin homology domain
GDS_CDC24_CS ProSitePatterns Guanine-nucleotide dissociation stimulator, CDC24, conserved site
PE/DAG-bd Pfam Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PH_domain SMART Pleckstrin homology domain
PH_domain ProSiteProfiles Pleckstrin homology domain
DBL_dom_sf SUPERFAMILY Dbl homology (DH) domain superfamily
PE/DAG-bd ProSiteProfiles Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
DH-domain Pfam Dbl homology (DH) domain
CH_dom_sf SUPERFAMILY CH domain superfamily
DH-domain SMART Dbl homology (DH) domain
CH-domain Pfam Calponin homology domain
DH-domain ProSiteProfiles Dbl homology (DH) domain
SH3_domain SMART SH3 domain
SH2 SMART SH2 domain
Vav1 PANTHER Protein vav1
SH2 Pfam SH2 domain
SH2 PRINTS SH2 domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

54 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
angiogenesis Hs biological process
phosphotyrosine residue binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
SH3/SH2 adaptor activity Hs molecular function
guanyl-nucleotide exchange factor activity Hs molecular function
Rho guanyl-nucleotide exchange factor activity Hs molecular function
GTPase activator activity Hs molecular function
epidermal growth factor receptor binding Hs molecular function
protein binding Hs molecular function
intracellular Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
cell-cell junction Hs cellular component
regulation of transcription, DNA-templated Hs biological process
vesicle fusion Hs biological process
phagocytosis Hs biological process
immune response Hs biological process
cellular response to DNA damage stimulus Hs biological process
signal transduction Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
integrin-mediated signaling pathway Hs biological process
small GTPase mediated signal transduction Hs biological process
regulation of cell size Hs biological process
positive regulation of signal transduction Hs biological process
cell migration Hs biological process
cytokine-mediated signaling pathway Hs biological process
cell projection assembly Hs biological process
lamellipodium assembly Hs biological process
platelet activation Hs biological process
T cell differentiation Hs biological process
neutrophil chemotaxis Hs biological process
Rac guanyl-nucleotide exchange factor activity Hs molecular function
regulation of Rho protein signal transduction Hs biological process
intracellular signal transduction Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
T cell activation Hs biological process
response to drug Hs biological process
positive regulation of apoptotic process Hs biological process
regulation of GTPase activity Hs biological process
positive regulation of GTPase activity Hs biological process
positive regulation of cell adhesion Hs biological process
positive regulation of natural killer cell mediated cytotoxicity Hs biological process
phosphatidylinositol phosphorylation Hs biological process
metal ion binding Hs molecular function
phosphatidylinositol-4,5-bisphosphate 3-kinase activity Hs molecular function
vascular endothelial growth factor receptor signaling pathway Hs biological process
ephrin receptor signaling pathway Hs biological process
B cell receptor signaling pathway Hs biological process
regulation of small GTPase mediated signal transduction Hs biological process
positive regulation of protein kinase B signaling Hs biological process
regulation of molecular function Hs biological process
extracellular exosome Hs cellular component
reactive oxygen species metabolic process Hs biological process

GO (Blast)

17 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
phosphotyrosine residue binding Hs molecular function 533 2.04e-177
transcription factor activity, sequence-specific DNA binding Hs molecular function 515 6.64e-171
SH3/SH2 adaptor activity Hs molecular function 520 2.42e-172
guanyl-nucleotide exchange factor activity Hs molecular function 533 2.04e-177
Rho guanyl-nucleotide exchange factor activity Hs molecular function 533 2.04e-177
GTPase activator activity Hs molecular function 520 2.42e-172
epidermal growth factor receptor binding Hs molecular function 533 2.04e-177
protein binding Hs molecular function 533 2.04e-177
intracellular Hs cellular component 520 2.42e-172
cytoplasm Hs cellular component 533 2.04e-177
cytosol Hs cellular component 533 2.04e-177
plasma membrane Hs cellular component 533 2.04e-177
cell-cell junction Hs cellular component 515 6.64e-171
Rac guanyl-nucleotide exchange factor activity Hs molecular function 520 2.42e-172
metal ion binding Hs molecular function 533 2.04e-177
phosphatidylinositol-4,5-bisphosphate 3-kinase activity Hs molecular function 515 6.64e-171
extracellular exosome Hs cellular component 520 2.42e-172

GO (InterProScan)

6 results

GO Term Analysis Type e-value
guanyl-nucleotide exchange factor activity ProSitePatterns molecular function
Rho guanyl-nucleotide exchange factor activity SMART molecular function 4.6E-51
protein binding Pfam molecular function 1.2E-18
small GTPase mediated signal transduction PANTHER biological process 2.9E-190
regulation of Rho protein signal transduction SMART biological process 4.6E-51
intracellular signal transduction ProSiteProfiles biological process 8.495

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