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GENE CARD

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Gene Card

Best human hits

IGF1R; INSR; INSRR

Species

B.schlosseri

Unique Gene ID

Boschl.g00069797

Gene Model ID

Boschl.CG.Botznik2013.chrUn.g69797

Location

chrUn:396477707..396478194

Transcript Models and Sequences

  Boschl.CG.Botznik2013.chrUn.g69797.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Tyr_kinase_cat_dom SMART Tyrosine-protein kinase, catalytic domain
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Ser-Thr/Tyr_kinase_cat_dom PRINTS Serine-threonine/tyrosine-protein kinase, catalytic domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type

GO (Blast)

43 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 132 2.29e-37
amyloid-beta binding Hs molecular function 130 2.28e-36
protein kinase activity Hs molecular function 132 2.29e-37
protein tyrosine kinase activity Hs molecular function 132 2.29e-37
transmembrane receptor protein tyrosine kinase activity Hs molecular function 132 2.29e-37
signal transducer, downstream of receptor, with protein tyrosine kinase activity Hs molecular function 130 2.28e-36
insulin-activated receptor activity Hs molecular function 130 2.28e-36
insulin-like growth factor-activated receptor activity Hs molecular function 132 2.29e-37
insulin receptor binding Hs molecular function 132 2.29e-37
insulin-like growth factor receptor binding Hs molecular function 130 2.28e-36
protein binding Hs molecular function 132 2.29e-37
insulin-like growth factor binding Hs molecular function 132 2.29e-37
ATP binding Hs molecular function 132 2.29e-37
GTP binding Hs molecular function 130 2.28e-36
intracellular Hs cellular component 130 2.28e-36
nuclear envelope Hs cellular component 130 2.28e-36
plasma membrane Hs cellular component 132 2.29e-37
integral component of plasma membrane Hs cellular component 132 2.29e-37
insulin receptor complex Hs cellular component 130 2.28e-36
caveola Hs cellular component 130 2.28e-36
external side of plasma membrane Hs cellular component 130 2.28e-36
endosome membrane Hs cellular component 130 2.28e-36
membrane Hs cellular component 132 2.29e-37
integral component of membrane Hs cellular component 132 2.29e-37
kinase activity Hs molecular function 132 2.29e-37
transferase activity Hs molecular function 132 2.29e-37
protein domain specific binding Hs molecular function 130 2.28e-36
nuclear lumen Hs cellular component 130 2.28e-36
insulin-like growth factor I binding Hs molecular function 132 2.29e-37
insulin-like growth factor II binding Hs molecular function 130 2.28e-36
dendrite membrane Hs cellular component 130 2.28e-36
neuronal cell body membrane Hs cellular component 130 2.28e-36
alphav-beta3 integrin-IGF-1-IGF1R complex Hs cellular component 132 2.29e-37
identical protein binding Hs molecular function 132 2.29e-37
intracellular membrane-bounded organelle Hs cellular component 132 2.29e-37
receptor complex Hs cellular component 132 2.29e-37
phosphatidylinositol 3-kinase binding Hs molecular function 132 2.29e-37
insulin binding Hs molecular function 132 2.29e-37
insulin receptor substrate binding Hs molecular function 132 2.29e-37
macromolecular complex binding Hs molecular function 130 2.28e-36
PTB domain binding Hs molecular function 130 2.28e-36
extracellular exosome Hs cellular component 130 2.28e-36
amyloid-beta complex Hs cellular component 130 2.28e-36

GO (InterProScan)

4 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 2.1E-30
protein tyrosine kinase activity SMART molecular function 1.5E-5
ATP binding ProSiteProfiles molecular function 14.535
protein phosphorylation Pfam biological process 2.1E-30