Gene Card
Best human hits
IGF1R; INSR; INSRR
Species
Unique Gene ID
Boschl.g00069797
Gene Model ID
Boschl.CG.Botznik2013.chrUn.g69797
Location
chrUn:396477707..396478194
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Tyr_kinase_cat_dom | SMART | Tyrosine-protein kinase, catalytic domain |
Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Ser-Thr/Tyr_kinase_cat_dom | PRINTS | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 132 | 2.29e-37 |
amyloid-beta binding | Hs | molecular function | 130 | 2.28e-36 |
protein kinase activity | Hs | molecular function | 132 | 2.29e-37 |
protein tyrosine kinase activity | Hs | molecular function | 132 | 2.29e-37 |
transmembrane receptor protein tyrosine kinase activity | Hs | molecular function | 132 | 2.29e-37 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity | Hs | molecular function | 130 | 2.28e-36 |
insulin-activated receptor activity | Hs | molecular function | 130 | 2.28e-36 |
insulin-like growth factor-activated receptor activity | Hs | molecular function | 132 | 2.29e-37 |
insulin receptor binding | Hs | molecular function | 132 | 2.29e-37 |
insulin-like growth factor receptor binding | Hs | molecular function | 130 | 2.28e-36 |
protein binding | Hs | molecular function | 132 | 2.29e-37 |
insulin-like growth factor binding | Hs | molecular function | 132 | 2.29e-37 |
ATP binding | Hs | molecular function | 132 | 2.29e-37 |
GTP binding | Hs | molecular function | 130 | 2.28e-36 |
intracellular | Hs | cellular component | 130 | 2.28e-36 |
nuclear envelope | Hs | cellular component | 130 | 2.28e-36 |
plasma membrane | Hs | cellular component | 132 | 2.29e-37 |
integral component of plasma membrane | Hs | cellular component | 132 | 2.29e-37 |
insulin receptor complex | Hs | cellular component | 130 | 2.28e-36 |
caveola | Hs | cellular component | 130 | 2.28e-36 |
external side of plasma membrane | Hs | cellular component | 130 | 2.28e-36 |
endosome membrane | Hs | cellular component | 130 | 2.28e-36 |
membrane | Hs | cellular component | 132 | 2.29e-37 |
integral component of membrane | Hs | cellular component | 132 | 2.29e-37 |
kinase activity | Hs | molecular function | 132 | 2.29e-37 |
transferase activity | Hs | molecular function | 132 | 2.29e-37 |
protein domain specific binding | Hs | molecular function | 130 | 2.28e-36 |
nuclear lumen | Hs | cellular component | 130 | 2.28e-36 |
insulin-like growth factor I binding | Hs | molecular function | 132 | 2.29e-37 |
insulin-like growth factor II binding | Hs | molecular function | 130 | 2.28e-36 |
dendrite membrane | Hs | cellular component | 130 | 2.28e-36 |
neuronal cell body membrane | Hs | cellular component | 130 | 2.28e-36 |
alphav-beta3 integrin-IGF-1-IGF1R complex | Hs | cellular component | 132 | 2.29e-37 |
identical protein binding | Hs | molecular function | 132 | 2.29e-37 |
intracellular membrane-bounded organelle | Hs | cellular component | 132 | 2.29e-37 |
receptor complex | Hs | cellular component | 132 | 2.29e-37 |
phosphatidylinositol 3-kinase binding | Hs | molecular function | 132 | 2.29e-37 |
insulin binding | Hs | molecular function | 132 | 2.29e-37 |
insulin receptor substrate binding | Hs | molecular function | 132 | 2.29e-37 |
macromolecular complex binding | Hs | molecular function | 130 | 2.28e-36 |
PTB domain binding | Hs | molecular function | 130 | 2.28e-36 |
extracellular exosome | Hs | cellular component | 130 | 2.28e-36 |
amyloid-beta complex | Hs | cellular component | 130 | 2.28e-36 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 2.1E-30 |
protein tyrosine kinase activity | SMART | molecular function | 1.5E-5 |
ATP binding | ProSiteProfiles | molecular function | 14.535 |
protein phosphorylation | Pfam | biological process | 2.1E-30 |