Gene Card
Best human hits
ARFGEF1; ARFGEF2; GBF1
Species
Unique Gene ID
Boschl.g00030702
Gene Model ID
Boschl.CG.Botznik2013.chrUn.g30702
Location
chrUn:200950744..200961295
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
8 results
| IPR Term | Analysis | Definition |
|---|---|---|
| ARM-type_fold | SUPERFAMILY | Armadillo-type fold |
| Sec7_dom_sf | SUPERFAMILY | Sec7 domain superfamily |
| Sec7_C_sf | Gene3D | Sec7, C-terminal domain superfamily |
| Sec7_dom | SMART | Sec7 domain |
| Sec7_dom | Pfam | Sec7 domain |
| Sec7_C | Pfam | Sec7, C-terminal |
| Sec7_N | Pfam | Guanine nucleotide exchange factor, N-terminal |
| Sec7_dom | ProSiteProfiles | Sec7 domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
47 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| Golgi membrane | Hs | cellular component |
| receptor recycling | Hs | biological process |
| guanyl-nucleotide exchange factor activity | Hs | molecular function |
| ARF guanyl-nucleotide exchange factor activity | Hs | molecular function |
| binding | Hs | molecular function |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| nucleoplasm | Hs | cellular component |
| nucleolus | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| endosome | Hs | cellular component |
| Golgi apparatus | Hs | cellular component |
| trans-Golgi network | Hs | cellular component |
| microtubule organizing center | Hs | cellular component |
| cytosol | Hs | cellular component |
| cytoskeleton | Hs | cellular component |
| axonemal microtubule | Hs | cellular component |
| exocytosis | Hs | biological process |
| Golgi to plasma membrane transport | Hs | biological process |
| Golgi organization | Hs | biological process |
| endosome organization | Hs | biological process |
| protein transport | Hs | biological process |
| membrane | Hs | cellular component |
| nuclear matrix | Hs | cellular component |
| myosin binding | Hs | molecular function |
| cell junction | Hs | cellular component |
| dendrite | Hs | cellular component |
| small nuclear ribonucleoprotein complex | Hs | cellular component |
| negative regulation of actin filament polymerization | Hs | biological process |
| neuron projection development | Hs | biological process |
| cytoplasmic vesicle | Hs | cellular component |
| regulation of ARF protein signal transduction | Hs | biological process |
| asymmetric synapse | Hs | cellular component |
| symmetric synapse | Hs | cellular component |
| protein kinase A regulatory subunit binding | Hs | molecular function |
| negative regulation of GTPase activity | Hs | biological process |
| intracellular signal transduction | Hs | biological process |
| cell projection | Hs | cellular component |
| dendritic spine | Hs | cellular component |
| synapse | Hs | cellular component |
| perinuclear region of cytoplasm | Hs | cellular component |
| GABA receptor binding | Hs | molecular function |
| positive regulation of protein kinase B signaling | Hs | biological process |
| recycling endosome | Hs | cellular component |
| regulation of molecular function | Hs | biological process |
| positive regulation of wound healing | Hs | biological process |
| regulation of establishment of cell polarity | Hs | biological process |
GO (Blast)
43 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 1219 | 0.0 |
| guanyl-nucleotide exchange factor activity | Hs | molecular function | 1219 | 0.0 |
| ARF guanyl-nucleotide exchange factor activity | Hs | molecular function | 1219 | 0.0 |
| binding | Hs | molecular function | 1219 | 0.0 |
| protein binding | Hs | molecular function | 1219 | 0.0 |
| phosphatidylinositol-3,4,5-trisphosphate binding | Hs | molecular function | 211 | 4.71e-56 |
| nucleus | Hs | cellular component | 1219 | 0.0 |
| nucleoplasm | Hs | cellular component | 1219 | 0.0 |
| nucleolus | Hs | cellular component | 1219 | 0.0 |
| cytoplasm | Hs | cellular component | 1219 | 0.0 |
| mitochondrion | Hs | cellular component | 211 | 4.71e-56 |
| endosome | Hs | cellular component | 1196 | 0.0 |
| peroxisome | Hs | cellular component | 211 | 4.71e-56 |
| endoplasmic reticulum lumen | Hs | cellular component | 211 | 4.71e-56 |
| endoplasmic reticulum-Golgi intermediate compartment | Hs | cellular component | 211 | 4.71e-56 |
| Golgi apparatus | Hs | cellular component | 1219 | 0.0 |
| Golgi stack | Hs | cellular component | 211 | 4.71e-56 |
| cis-Golgi network | Hs | cellular component | 211 | 4.71e-56 |
| trans-Golgi network | Hs | cellular component | 1219 | 0.0 |
| lipid droplet | Hs | cellular component | 211 | 4.71e-56 |
| microtubule organizing center | Hs | cellular component | 1196 | 0.0 |
| cytosol | Hs | cellular component | 1219 | 0.0 |
| cytoskeleton | Hs | cellular component | 1196 | 0.0 |
| axonemal microtubule | Hs | cellular component | 1196 | 0.0 |
| lipid binding | Hs | molecular function | 211 | 4.71e-56 |
| membrane | Hs | cellular component | 1219 | 0.0 |
| nuclear matrix | Hs | cellular component | 1219 | 0.0 |
| myosin binding | Hs | molecular function | 1219 | 0.0 |
| cell junction | Hs | cellular component | 1196 | 0.0 |
| dendrite | Hs | cellular component | 1196 | 0.0 |
| small nuclear ribonucleoprotein complex | Hs | cellular component | 1219 | 0.0 |
| cell leading edge | Hs | cellular component | 211 | 4.71e-56 |
| cytoplasmic vesicle | Hs | cellular component | 1196 | 0.0 |
| asymmetric synapse | Hs | cellular component | 1196 | 0.0 |
| symmetric synapse | Hs | cellular component | 1196 | 0.0 |
| protein kinase A regulatory subunit binding | Hs | molecular function | 1219 | 0.0 |
| cell projection | Hs | cellular component | 1196 | 0.0 |
| dendritic spine | Hs | cellular component | 1196 | 0.0 |
| synapse | Hs | cellular component | 1196 | 0.0 |
| perinuclear region of cytoplasm | Hs | cellular component | 1219 | 0.0 |
| GABA receptor binding | Hs | molecular function | 1196 | 0.0 |
| recycling endosome | Hs | cellular component | 1196 | 0.0 |
| phosphatidylinositol-3,5-bisphosphate binding | Hs | molecular function | 211 | 4.71e-56 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| ARF guanyl-nucleotide exchange factor activity | SMART | molecular function | 2.6E-91 |
| binding | SUPERFAMILY | molecular function | 1.28E-11 |
| regulation of ARF protein signal transduction | SMART | biological process | 2.6E-91 |
