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GENE CARD

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Gene Card

Best human hits

TRAF3; TRAF5; TRAF6

Species

B.schlosseri

Unique Gene ID

Boschl.g00010617

Gene Model ID

Boschl.CG.Botznik2013.chrUn.g10617

Location

chrUn:68454406..68463415

Transcript Models and Sequences

  Boschl.CG.Botznik2013.chrUn.g10617.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
Znf_RING/FYVE/PHD Gene3D Zinc finger, RING/FYVE/PHD-type
Znf_TRAF Pfam Zinc finger, TRAF-type
TRAF-like SUPERFAMILY TRAF-like
Znf_TRAF ProSiteProfiles Zinc finger, TRAF-type

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

73 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
activation of MAPK activity Hs biological process
protein polyubiquitination Hs biological process
ossification Hs biological process
neural tube closure Hs biological process
toll-like receptor signaling pathway Hs biological process
immune system process Hs biological process
MyD88-dependent toll-like receptor signaling pathway Hs biological process
ubiquitin-protein transferase activity Hs molecular function
tumor necrosis factor receptor binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
lipid droplet Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
cell cortex Hs cellular component
immune response Hs biological process
cellular response to DNA damage stimulus Hs biological process
signal transduction Hs biological process
I-kappaB kinase/NF-kappaB signaling Hs biological process
activation of NF-kappaB-inducing kinase activity Hs biological process
JNK cascade Hs biological process
zinc ion binding Hs molecular function
animal organ morphogenesis Hs biological process
cytoplasmic side of plasma membrane Hs cellular component
endosome membrane Hs cellular component
protein ubiquitination Hs biological process
protein deubiquitination Hs biological process
transferase activity Hs molecular function
cytokine-mediated signaling pathway Hs biological process
antigen processing and presentation of exogenous peptide antigen via MHC class II Hs biological process
protein kinase binding Hs molecular function
osteoclast differentiation Hs biological process
membrane protein intracellular domain proteolysis Hs biological process
positive regulation of protein ubiquitination Hs biological process
mitogen-activated protein kinase kinase kinase binding Hs molecular function
ubiquitin conjugating enzyme binding Hs molecular function
ubiquitin protein ligase binding Hs molecular function
thioesterase binding Hs molecular function
activation of protein kinase activity Hs biological process
macromolecular complex Hs cellular component
toll-like receptor 9 signaling pathway Hs biological process
CD40 receptor complex Hs cellular component
Fc-epsilon receptor signaling pathway Hs biological process
T-helper 1 type immune response Hs biological process
identical protein binding Hs molecular function
histone deacetylase binding Hs molecular function
regulation of apoptotic process Hs biological process
myeloid dendritic cell differentiation Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
protein kinase B binding Hs molecular function
positive regulation of JUN kinase activity Hs biological process
positive regulation of interleukin-6 biosynthetic process Hs biological process
bone resorption Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
bone remodeling Hs biological process
metal ion binding Hs molecular function
protein N-terminus binding Hs molecular function
cell development Hs biological process
perinuclear region of cytoplasm Hs cellular component
T cell receptor signaling pathway Hs biological process
positive regulation of sequence-specific DNA binding transcription factor activity Hs biological process
positive regulation of NF-kappaB transcription factor activity Hs biological process
protein autoubiquitination Hs biological process
ubiquitin protein ligase activity Hs molecular function
interleukin-1-mediated signaling pathway Hs biological process
protein K63-linked ubiquitination Hs biological process
cellular response to lipopolysaccharide Hs biological process

GO (Blast)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
ubiquitin-protein transferase activity Hs molecular function 115 3.46e-29
signal transducer activity Hs molecular function 67.4 1.42e-12
tumor necrosis factor receptor binding Hs molecular function 115 3.46e-29
protein binding Hs molecular function 115 3.46e-29
nucleus Hs cellular component 115 3.46e-29
cytoplasm Hs cellular component 115 3.46e-29
mitochondrion Hs cellular component 67.4 1.42e-12
endosome Hs cellular component 67.4 1.42e-12
lipid droplet Hs cellular component 115 3.46e-29
centrosome Hs cellular component 84.3 3.34e-18
cytosol Hs cellular component 115 3.46e-29
plasma membrane Hs cellular component 115 3.46e-29
cell cortex Hs cellular component 115 3.46e-29
zinc ion binding Hs molecular function 115 3.46e-29
cytoplasmic side of plasma membrane Hs cellular component 115 3.46e-29
endosome membrane Hs cellular component 115 3.46e-29
transferase activity Hs molecular function 115 3.46e-29
protein kinase binding Hs molecular function 115 3.46e-29
protein phosphatase binding Hs molecular function 67.4 1.42e-12
mitogen-activated protein kinase kinase kinase binding Hs molecular function 115 3.46e-29
ubiquitin conjugating enzyme binding Hs molecular function 115 3.46e-29
ubiquitin protein ligase binding Hs molecular function 115 3.46e-29
thioesterase binding Hs molecular function 115 3.46e-29
macromolecular complex Hs cellular component 115 3.46e-29
CD40 receptor complex Hs cellular component 115 3.46e-29
identical protein binding Hs molecular function 115 3.46e-29
histone deacetylase binding Hs molecular function 115 3.46e-29
protein kinase B binding Hs molecular function 115 3.46e-29
metal ion binding Hs molecular function 115 3.46e-29
protein N-terminus binding Hs molecular function 115 3.46e-29
perinuclear region of cytoplasm Hs cellular component 115 3.46e-29
ubiquitin protein ligase activity Hs molecular function 115 3.46e-29

GO (InterProScan)

2 results

GO Term Analysis Type e-value
protein binding SUPERFAMILY molecular function 1.5E-6
zinc ion binding Pfam molecular function 1.4E-7