Gene Card
Best human hits
ACVR1B; ACVR1C; TGFBR1
Species
Unique Gene ID
Boschl.g00010147
Gene Model ID
Boschl.CG.Botznik2013.chrUn.g10147
Location
chrUn:65497806..65502334
Transcript Models and Sequences
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
GS_dom | Pfam | GS domain |
Activin_recp | Pfam | Activin types I and II receptor domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Prot_kinase_dom | Pfam | Protein kinase domain |
GS_dom | ProSiteProfiles | GS domain |
Prot_kinase_dom | SMART | Protein kinase domain |
GS_dom | SMART | GS domain |
TGFB_receptor | PANTHER | Ser/Thr protein kinase, TGFB receptor |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 415 | 2.10e-141 |
protein kinase activity | Hs | molecular function | 415 | 2.10e-141 |
protein serine/threonine kinase activity | Hs | molecular function | 415 | 2.10e-141 |
transmembrane receptor protein serine/threonine kinase activity | Hs | molecular function | 415 | 2.10e-141 |
signal transducer, downstream of receptor, with serine/threonine kinase activity | Hs | molecular function | 415 | 2.10e-141 |
transforming growth factor beta-activated receptor activity | Hs | molecular function | 408 | 2.17e-138 |
transforming growth factor beta receptor activity, type I | Hs | molecular function | 408 | 2.17e-138 |
signal transducer activity, downstream of receptor | Hs | molecular function | 408 | 2.17e-138 |
receptor binding | Hs | molecular function | 408 | 2.17e-138 |
type II transforming growth factor beta receptor binding | Hs | molecular function | 408 | 2.17e-138 |
protein binding | Hs | molecular function | 408 | 2.17e-138 |
ATP binding | Hs | molecular function | 415 | 2.10e-141 |
cell | Hs | cellular component | 408 | 2.17e-138 |
endosome | Hs | cellular component | 408 | 2.17e-138 |
cytosol | Hs | cellular component | 371 | 2.28e-123 |
plasma membrane | Hs | cellular component | 415 | 2.10e-141 |
integral component of plasma membrane | Hs | cellular component | 371 | 2.28e-123 |
bicellular tight junction | Hs | cellular component | 408 | 2.17e-138 |
cell surface | Hs | cellular component | 408 | 2.17e-138 |
membrane | Hs | cellular component | 415 | 2.10e-141 |
integral component of membrane | Hs | cellular component | 415 | 2.10e-141 |
kinase activity | Hs | molecular function | 415 | 2.10e-141 |
activin receptor activity, type I | Hs | molecular function | 415 | 2.10e-141 |
transferase activity | Hs | molecular function | 415 | 2.10e-141 |
activin-activated receptor activity | Hs | molecular function | 371 | 2.28e-123 |
growth factor binding | Hs | molecular function | 415 | 2.10e-141 |
cell junction | Hs | cellular component | 408 | 2.17e-138 |
ubiquitin protein ligase binding | Hs | molecular function | 371 | 2.28e-123 |
inhibin binding | Hs | molecular function | 371 | 2.28e-123 |
nodal binding | Hs | molecular function | 415 | 2.10e-141 |
intracellular membrane-bounded organelle | Hs | cellular component | 408 | 2.17e-138 |
receptor complex | Hs | cellular component | 408 | 2.17e-138 |
membrane raft | Hs | cellular component | 408 | 2.17e-138 |
SMAD binding | Hs | molecular function | 408 | 2.17e-138 |
metal ion binding | Hs | molecular function | 415 | 2.10e-141 |
activin receptor complex | Hs | cellular component | 415 | 2.10e-141 |
activin binding | Hs | molecular function | 371 | 2.28e-123 |
transforming growth factor beta binding | Hs | molecular function | 408 | 2.17e-138 |
transforming growth factor beta receptor complex | Hs | cellular component | 408 | 2.17e-138 |
extracellular exosome | Hs | cellular component | 371 | 2.28e-123 |
I-SMAD binding | Hs | molecular function | 408 | 2.17e-138 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 8.0E-36 |
transmembrane receptor protein serine/threonine kinase activity | Pfam | molecular function | 7.1E-6 |
signal transducer, downstream of receptor, with serine/threonine kinase activity | PANTHER | molecular function | 5.7E-146 |
ATP binding | PANTHER | molecular function | 5.7E-146 |
protein phosphorylation | Pfam | biological process | 8.0E-36 |
transmembrane receptor protein serine/threonine kinase signaling pathway | PANTHER | biological process | 5.7E-146 |
membrane | PANTHER | cellular component | 5.7E-146 |