Gene Card
Best human hits
DMC1; RAD51; RAD51B
Species
Unique Gene ID
Boschl.g00007745
Gene Model ID
Boschl.CG.Botznik2013.chrUn.g07745
Location
chrUn:50512053..50516982
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
RecA_monomer-monomer_interface | ProSiteProfiles | DNA recombination and repair protein RecA, monomer-monomer interface |
RecA_ATP-bd | ProSiteProfiles | DNA recombination and repair protein RecA-like, ATP-binding domain |
AAA+_ATPase | SMART | AAA+ ATPase domain |
DNA_recomb/repair_Rad51_C | Pfam | DNA recombination and repair protein Rad51-like, C-terminal |
Rad51_DMC1_RadA | CDD | Rad51/DMC1/RadA |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
recombinase activity | Hs | molecular function |
nucleotide binding | Hs | molecular function |
nuclear chromosome | Hs | cellular component |
four-way junction DNA binding | Hs | molecular function |
telomere maintenance via recombination | Hs | biological process |
double-strand break repair via homologous recombination | Hs | biological process |
DNA recombinase assembly | Hs | biological process |
DNA synthesis involved in DNA repair | Hs | biological process |
strand displacement | Hs | biological process |
nuclear chromosome, telomeric region | Hs | cellular component |
chromatin | Hs | cellular component |
nuclear chromatin | Hs | cellular component |
condensed chromosome | Hs | cellular component |
condensed nuclear chromosome | Hs | cellular component |
lateral element | Hs | cellular component |
DNA binding | Hs | molecular function |
double-stranded DNA binding | Hs | molecular function |
single-stranded DNA binding | Hs | molecular function |
endodeoxyribonuclease activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
nucleolus | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
microtubule organizing center | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
DNA metabolic process | Hs | biological process |
DNA unwinding involved in DNA replication | Hs | biological process |
DNA repair | Hs | biological process |
DNA recombination | Hs | biological process |
mitotic recombination | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
reciprocal meiotic recombination | Hs | biological process |
protein C-terminus binding | Hs | molecular function |
DNA-dependent ATPase activity | Hs | molecular function |
regulation of double-strand break repair via homologous recombination | Hs | biological process |
telomere maintenance via telomere lengthening | Hs | biological process |
PML body | Hs | cellular component |
replication fork processing | Hs | biological process |
macromolecular complex | Hs | cellular component |
site of double-strand break | Hs | cellular component |
interstrand cross-link repair | Hs | biological process |
strand invasion | Hs | biological process |
identical protein binding | Hs | molecular function |
single-stranded DNA-dependent ATPase activity | Hs | molecular function |
perinuclear region of cytoplasm | Hs | cellular component |
protein homooligomerization | Hs | biological process |
meiotic cell cycle | Hs | biological process |
DNA polymerase binding | Hs | molecular function |
chromosome organization involved in meiotic cell cycle | Hs | biological process |
cellular response to ionizing radiation | Hs | biological process |
mitotic recombination-dependent replication fork processing | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
recombinase activity | Hs | molecular function | 405 | 1.73e-143 |
nucleotide binding | Hs | molecular function | 405 | 1.73e-143 |
nuclear chromosome | Hs | cellular component | 405 | 1.73e-143 |
four-way junction DNA binding | Hs | molecular function | 405 | 1.73e-143 |
chromosome, telomeric region | Hs | cellular component | 250 | 2.22e-82 |
nuclear chromosome, telomeric region | Hs | cellular component | 405 | 1.73e-143 |
chromatin | Hs | cellular component | 405 | 1.73e-143 |
nuclear chromatin | Hs | cellular component | 405 | 1.73e-143 |
condensed chromosome | Hs | cellular component | 405 | 1.73e-143 |
condensed nuclear chromosome | Hs | cellular component | 405 | 1.73e-143 |
lateral element | Hs | cellular component | 405 | 1.73e-143 |
DNA binding | Hs | molecular function | 405 | 1.73e-143 |
double-stranded DNA binding | Hs | molecular function | 405 | 1.73e-143 |
single-stranded DNA binding | Hs | molecular function | 405 | 1.73e-143 |
endodeoxyribonuclease activity | Hs | molecular function | 405 | 1.73e-143 |
protein binding | Hs | molecular function | 405 | 1.73e-143 |
ATP binding | Hs | molecular function | 405 | 1.73e-143 |
nucleus | Hs | cellular component | 405 | 1.73e-143 |
nucleoplasm | Hs | cellular component | 405 | 1.73e-143 |
replication fork | Hs | cellular component | 83.2 | 3.34e-18 |
chromosome | Hs | cellular component | 250 | 2.22e-82 |
nucleolus | Hs | cellular component | 405 | 1.73e-143 |
cytoplasm | Hs | cellular component | 405 | 1.73e-143 |
mitochondrion | Hs | cellular component | 405 | 1.73e-143 |
mitochondrial matrix | Hs | cellular component | 405 | 1.73e-143 |
microtubule organizing center | Hs | cellular component | 405 | 1.73e-143 |
cytosol | Hs | cellular component | 405 | 1.73e-143 |
cytoskeleton | Hs | cellular component | 405 | 1.73e-143 |
protein C-terminus binding | Hs | molecular function | 405 | 1.73e-143 |
DNA-dependent ATPase activity | Hs | molecular function | 405 | 1.73e-143 |
membrane | Hs | cellular component | 83.2 | 3.34e-18 |
integral component of membrane | Hs | cellular component | 83.2 | 3.34e-18 |
PML body | Hs | cellular component | 405 | 1.73e-143 |
macromolecular complex | Hs | cellular component | 405 | 1.73e-143 |
Rad51B-Rad51C-Rad51D-XRCC2 complex | Hs | cellular component | 83.2 | 3.34e-18 |
site of double-strand break | Hs | cellular component | 405 | 1.73e-143 |
identical protein binding | Hs | molecular function | 405 | 1.73e-143 |
single-stranded DNA-dependent ATPase activity | Hs | molecular function | 405 | 1.73e-143 |
perinuclear region of cytoplasm | Hs | cellular component | 405 | 1.73e-143 |
DNA polymerase binding | Hs | molecular function | 405 | 1.73e-143 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
DNA binding | CDD | molecular function | 4.70615E-134 |
ATP binding | ProSiteProfiles | molecular function | 20.766 |
DNA metabolic process | ProSiteProfiles | biological process | 20.766 |
DNA repair | ProSiteProfiles | biological process | 35.551 |
DNA-dependent ATPase activity | ProSiteProfiles | molecular function | 20.766 |