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GENE CARD

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Gene Card

Best human hits

E2F2; E2F3

Species

B.schlosseri

Unique Gene ID

Boschl.g00053779

Gene Model ID

Boschl.CG.Botznik2013.chr13.g53779

Location

chr13:4376099..4381367

Transcript Models and Sequences

  Boschl.CG.Botznik2013.chr13.g53779.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
E2F_WHTH_DNA-bd_dom Pfam E2F/DP family, winged-helix DNA-binding domain
WH_DNA-bd_sf SUPERFAMILY Winged helix DNA-binding domain superfamily
E2F_CC-MB CDD E2F transcription factor, CC-MB domain
E2F PANTHER E2F Family
WH-like_DNA-bd_sf Gene3D Winged helix-like DNA-binding domain superfamily
E2F-DP_heterodim SUPERFAMILY E2F-DP heterodimerization region
E2F_CC-MB Pfam E2F transcription factor, CC-MB domain
E2F_WHTH_DNA-bd_dom SMART E2F/DP family, winged-helix DNA-binding domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
core promoter binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
cell cycle Hs biological process
transcription factor binding Hs molecular function
positive regulation of cell proliferation Hs biological process
sequence-specific DNA binding Hs molecular function
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
protein dimerization activity Hs molecular function
regulation of cell cycle Hs biological process
intrinsic apoptotic signaling pathway by p53 class mediator Hs biological process
RNA polymerase II transcription factor complex Hs cellular component
negative regulation of sprouting angiogenesis Hs biological process
DNA damage checkpoint Hs biological process
negative regulation of transcription from RNA polymerase II promoter Hs biological process
nuclear chromatin Hs cellular component
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
cytoplasm Hs cellular component
mitochondrion Hs cellular component
centrosome Hs cellular component
apoptotic process Hs biological process
spermatogenesis Hs biological process
intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
positive regulation of gene expression Hs biological process
protein kinase binding Hs molecular function
forebrain development Hs biological process
macromolecular complex Hs cellular component
Rb-E2F complex Hs cellular component
positive regulation of apoptotic process Hs biological process
negative regulation of DNA binding Hs biological process
transcription regulatory region DNA binding Hs molecular function
negative regulation of transcription, DNA-templated Hs biological process
mRNA stabilization Hs biological process
cellular response to hypoxia Hs biological process
cellular response to xenobiotic stimulus Hs biological process
negative regulation of transcription involved in G1/S transition of mitotic cell cycle Hs biological process
regulation of G1/S transition of mitotic cell cycle Hs biological process

GO (Blast)

14 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 191 1.39e-56
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 191 1.39e-56
core promoter binding Hs molecular function 191 1.39e-56
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 191 1.39e-56
DNA binding Hs molecular function 191 1.39e-56
transcription factor activity, sequence-specific DNA binding Hs molecular function 191 1.39e-56
protein binding Hs molecular function 191 1.39e-56
nucleus Hs cellular component 191 1.39e-56
nucleoplasm Hs cellular component 191 1.39e-56
transcription factor complex Hs cellular component 191 1.39e-56
transcription factor binding Hs molecular function 179 1.43e-52
sequence-specific DNA binding Hs molecular function 191 1.39e-56
protein dimerization activity Hs molecular function 191 1.39e-56
RNA polymerase II transcription factor complex Hs cellular component 191 1.39e-56

GO (InterProScan)

4 results

GO Term Analysis Type e-value
transcription factor activity, sequence-specific DNA binding SMART molecular function 1.7E-29
transcription factor complex SMART cellular component 1.7E-29
regulation of transcription, DNA-templated SMART biological process 1.7E-29
protein dimerization activity CDD molecular function 1.27203E-26

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