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Gene Card

Best human hits

MLH1; PMS1; PMS2

Species

B.schlosseri

Unique Gene ID

Boschl.g00048063

Gene Model ID

Boschl.CG.Botznik2013.chr10.g48063

Location

chr10:8336404..8338837

Transcript Models and Sequences

  Boschl.CG.Botznik2013.chr10.g48063.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
MutL_C SMART MutL, C-terminal, dimerisation
DNA_mismatch_repair_fam TIGRFAM DNA mismatch repair protein family
Ribosomal_S5_D2-typ_fold_subgr Gene3D Ribosomal protein S5 domain 2-type fold, subgroup
HATPase_C_sf Gene3D Histidine kinase/HSP90-like ATPase superfamily
MutL_C_sf SUPERFAMILY MutL, C-terminal domain superfamily
DNA_mismatch_repair_CS ProSitePatterns DNA mismatch repair, conserved site
Ribosomal_S5_D2-typ_fold SUPERFAMILY Ribosomal protein S5 domain 2-type fold
DNA_mismatch_repair_C Pfam DNA mismatch repair protein, C-terminal
HATPase_C_sf SUPERFAMILY Histidine kinase/HSP90-like ATPase superfamily
HATPase_C CDD Histidine kinase/HSP90-like ATPase
DNA_mismatch_repair_C SMART DNA mismatch repair protein, C-terminal
MutL_C Pfam MutL, C-terminal, dimerisation

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
DNA binding Hs molecular function
single-stranded DNA binding Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
DNA repair Hs biological process
mismatch repair Hs biological process
cellular response to DNA damage stimulus Hs biological process
microtubule cytoskeleton Hs cellular component
somatic hypermutation of immunoglobulin genes Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
mismatched DNA binding Hs molecular function
single base insertion or deletion binding Hs molecular function
MutLalpha complex Hs cellular component
MutSalpha complex binding Hs molecular function
cytoplasmic ribonucleoprotein granule Hs cellular component
response to drug Hs biological process
nucleic acid phosphodiester bond hydrolysis Hs biological process

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 150 1.12e-37
condensed chromosome Hs cellular component 150 1.12e-37
condensed nuclear chromosome Hs cellular component 150 1.12e-37
synaptonemal complex Hs cellular component 150 1.12e-37
male germ cell nucleus Hs cellular component 150 1.12e-37
DNA binding Hs molecular function 366 7.04e-114
chromatin binding Hs molecular function 150 1.12e-37
single-stranded DNA binding Hs molecular function 366 7.04e-114
nuclease activity Hs molecular function 366 7.04e-114
endonuclease activity Hs molecular function 366 7.04e-114
protein binding Hs molecular function 366 7.04e-114
ATP binding Hs molecular function 366 7.04e-114
nucleus Hs cellular component 366 7.04e-114
nucleoplasm Hs cellular component 366 7.04e-114
chromosome Hs cellular component 150 1.12e-37
chiasma Hs cellular component 150 1.12e-37
late recombination nodule Hs cellular component 150 1.12e-37
cytosol Hs cellular component 366 7.04e-114
plasma membrane Hs cellular component 366 7.04e-114
microtubule cytoskeleton Hs cellular component 366 7.04e-114
membrane Hs cellular component 150 1.12e-37
hydrolase activity Hs molecular function 366 7.04e-114
ATPase activity Hs molecular function 366 7.04e-114
mismatched DNA binding Hs molecular function 366 7.04e-114
guanine/thymine mispair binding Hs molecular function 150 1.12e-37
single base insertion or deletion binding Hs molecular function 366 7.04e-114
mismatch repair complex Hs cellular component 150 1.12e-37
MutLalpha complex Hs cellular component 366 7.04e-114
MutSalpha complex binding Hs molecular function 366 7.04e-114
cytoplasmic ribonucleoprotein granule Hs cellular component 366 7.04e-114

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ATP binding TIGRFAM molecular function 3.2E-85
mismatch repair TIGRFAM biological process 3.2E-85
mismatched DNA binding TIGRFAM molecular function 3.2E-85

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