Gene Card
Best human hits
HACE1; HUWE1; UBR5
Species
Unique Gene ID
Boleac.g00008105
Gene Model ID
Boleac.CG.SB_v3.S346.g08105
Location
S346:31595..81247
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
13 results
| IPR Term | Analysis | Definition |
|---|---|---|
| PABP-dom | SUPERFAMILY | PABC (PABP) domain |
| HECT_dom | ProSiteProfiles | HECT domain |
| Znf_UBR | SMART | Zinc finger, UBR-type |
| PABP_HYD | ProSiteProfiles | Polyadenylate-binding protein/Hyperplastic disc protein |
| RCC1/BLIP-II | SUPERFAMILY | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
| E3_UbLigase_EDD_UBA | Pfam | E3 ubiquitin ligase EDD, ubiquitin-associated domain |
| Hect_E3_ubiquitin_ligase | SUPERFAMILY | HECT, E3 ligase catalytic domain |
| PABP_HYD | SMART | Polyadenylate-binding protein/Hyperplastic disc protein |
| HECT_dom | SMART | HECT domain |
| PABP_HYD | Pfam | Polyadenylate-binding protein/Hyperplastic disc protein |
| Znf_UBR | ProSiteProfiles | Zinc finger, UBR-type |
| E3_UbLigase_EDD_UBA | CDD | E3 ubiquitin ligase EDD, ubiquitin-associated domain |
| HECT_dom | Pfam | HECT domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
28 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| protein polyubiquitination | Hs | biological process |
| RNA binding | Hs | molecular function |
| ubiquitin-protein transferase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| nucleoplasm | Hs | cellular component |
| cytosol | Hs | cellular component |
| DNA repair | Hs | biological process |
| ubiquitin-dependent protein catabolic process | Hs | biological process |
| cellular response to DNA damage stimulus | Hs | biological process |
| zinc ion binding | Hs | molecular function |
| cell proliferation | Hs | biological process |
| positive regulation of gene expression | Hs | biological process |
| membrane | Hs | cellular component |
| protein ubiquitination | Hs | biological process |
| transferase activity | Hs | molecular function |
| macromolecular complex | Hs | cellular component |
| positive regulation of protein import into nucleus, translocation | Hs | biological process |
| ubiquitin-ubiquitin ligase activity | Hs | molecular function |
| ubiquitin binding | Hs | molecular function |
| metal ion binding | Hs | molecular function |
| perinuclear region of cytoplasm | Hs | cellular component |
| progesterone receptor signaling pathway | Hs | biological process |
| ubiquitin protein ligase activity | Hs | molecular function |
| protein K48-linked ubiquitination | Hs | biological process |
| positive regulation of canonical Wnt signaling pathway | Hs | biological process |
| negative regulation of histone H2A K63-linked ubiquitination | Hs | biological process |
| negative regulation of double-strand break repair | Hs | biological process |
GO (Blast)
29 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 92.0 | 4.65e-18 |
| DNA binding | Hs | molecular function | 90.9 | 1.36e-17 |
| RNA binding | Hs | molecular function | 830 | 0.0 |
| ubiquitin-protein transferase activity | Hs | molecular function | 830 | 0.0 |
| binding | Hs | molecular function | 90.9 | 1.36e-17 |
| protein binding | Hs | molecular function | 830 | 0.0 |
| extracellular region | Hs | cellular component | 90.9 | 1.36e-17 |
| nucleus | Hs | cellular component | 830 | 0.0 |
| nucleoplasm | Hs | cellular component | 830 | 0.0 |
| cytoplasm | Hs | cellular component | 92.0 | 4.65e-18 |
| endoplasmic reticulum | Hs | cellular component | 92.0 | 4.65e-18 |
| Golgi apparatus | Hs | cellular component | 92.0 | 4.65e-18 |
| cytosol | Hs | cellular component | 830 | 0.0 |
| zinc ion binding | Hs | molecular function | 830 | 0.0 |
| membrane | Hs | cellular component | 830 | 0.0 |
| nuclear body | Hs | cellular component | 92.0 | 4.65e-18 |
| transferase activity | Hs | molecular function | 830 | 0.0 |
| Rab GTPase binding | Hs | molecular function | 92.0 | 4.65e-18 |
| Golgi cisterna membrane | Hs | cellular component | 92.0 | 4.65e-18 |
| macromolecular complex | Hs | cellular component | 830 | 0.0 |
| ubiquitin-ubiquitin ligase activity | Hs | molecular function | 830 | 0.0 |
| secretory granule lumen | Hs | cellular component | 90.9 | 1.36e-17 |
| ubiquitin binding | Hs | molecular function | 830 | 0.0 |
| metal ion binding | Hs | molecular function | 830 | 0.0 |
| Rac GTPase binding | Hs | molecular function | 92.0 | 4.65e-18 |
| perinuclear region of cytoplasm | Hs | cellular component | 830 | 0.0 |
| ubiquitin protein ligase activity | Hs | molecular function | 830 | 0.0 |
| extracellular exosome | Hs | cellular component | 90.9 | 1.36e-17 |
| ficolin-1-rich granule lumen | Hs | cellular component | 90.9 | 1.36e-17 |
GO (InterProScan)
4 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| RNA binding | SUPERFAMILY | molecular function | 2.62E-13 |
| ubiquitin-protein transferase activity | SMART | molecular function | 2.6E-55 |
| zinc ion binding | SMART | molecular function | 2.0E-23 |
| ubiquitin binding | Pfam | molecular function | 8.6E-29 |
