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GENE CARD

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Gene Card

Best human hits

PKD1; PKD2; PKD2L1

Species

B.leachii

Unique Gene ID

Boleac.g00007687

Gene Model ID

Boleac.CG.SB_v3.S323.g07687

Location

S323:11228..17445

Transcript Models and Sequences

  Boleac.CG.SB_v3.S323.g07687.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

2 results

IPR Term Analysis Definition
PKD1_2_channel Pfam Polycystin cation channel, PKD1/PKD2
PC1 PRINTS Polycystic kidney disease type 1 protein

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

60 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
Golgi membrane Hs cellular component
cartilage condensation Hs biological process
blood vessel development Hs biological process
kidney development Hs biological process
liver development Hs biological process
polycystin complex Hs cellular component
calcium channel activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
Golgi apparatus Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
cilium Hs cellular component
protein export from nucleus Hs biological process
nitrogen compound metabolic process Hs biological process
calcium ion transport Hs biological process
cell cycle arrest Hs biological process
homophilic cell adhesion via plasma membrane adhesion molecules Hs biological process
cell-matrix adhesion Hs biological process
positive regulation of cytosolic calcium ion concentration Hs biological process
JAK-STAT cascade Hs biological process
heart development Hs biological process
anatomical structure morphogenesis Hs biological process
cell surface Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
basolateral plasma membrane Hs cellular component
lateral plasma membrane Hs cellular component
peptidyl-serine phosphorylation Hs biological process
protein kinase binding Hs molecular function
protein domain specific binding Hs molecular function
spinal cord development Hs biological process
neural tube development Hs biological process
establishment of cell polarity Hs biological process
regulation of cell adhesion Hs biological process
carbohydrate binding Hs molecular function
Golgi-associated vesicle membrane Hs cellular component
motile cilium Hs cellular component
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle Hs biological process
positive regulation of protein binding Hs biological process
response to fluid shear stress Hs biological process
lymph vessel morphogenesis Hs biological process
cytoplasmic sequestering of transcription factor Hs biological process
cell projection Hs cellular component
skin development Hs biological process
ion channel binding Hs molecular function
positive regulation of transcription from RNA polymerase II promoter Hs biological process
digestive tract development Hs biological process
branching morphogenesis of an epithelial tube Hs biological process
genitalia development Hs biological process
detection of mechanical stimulus Hs biological process
cartilage development Hs biological process
ciliary membrane Hs cellular component
regulation of mitotic spindle organization Hs biological process
regulation of proteasomal protein catabolic process Hs biological process
extracellular exosome Hs cellular component
calcium ion transmembrane transport Hs biological process
renal system development Hs biological process
cell-cell adhesion Hs biological process

GO (Blast)

69 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
Golgi membrane Hs cellular component 170 1.70e-42
polycystin complex Hs cellular component 170 1.70e-42
receptor binding Hs molecular function 108 1.04e-23
calcium activated cation channel activity Hs molecular function 114 1.11e-25
voltage-gated ion channel activity Hs molecular function 108 1.04e-23
voltage-gated calcium channel activity Hs molecular function 108 1.04e-23
voltage-gated sodium channel activity Hs molecular function 108 1.04e-23
voltage-gated potassium channel activity Hs molecular function 108 1.04e-23
cation channel activity Hs molecular function 114 1.11e-25
calcium channel activity Hs molecular function 170 1.70e-42
potassium channel activity Hs molecular function 108 1.04e-23
sodium channel activity Hs molecular function 114 1.11e-25
calcium ion binding Hs molecular function 114 1.11e-25
protein binding Hs molecular function 170 1.70e-42
nucleus Hs cellular component 170 1.70e-42
cytoplasm Hs cellular component 170 1.70e-42
endoplasmic reticulum Hs cellular component 114 1.11e-25
endoplasmic reticulum membrane Hs cellular component 108 1.04e-23
Golgi apparatus Hs cellular component 170 1.70e-42
plasma membrane Hs cellular component 170 1.70e-42
integral component of plasma membrane Hs cellular component 170 1.70e-42
cell-cell junction Hs cellular component 108 1.04e-23
cilium Hs cellular component 170 1.70e-42
cytoskeletal protein binding Hs molecular function 114 1.11e-25
cation transmembrane transporter activity Hs molecular function 114 1.11e-25
basal plasma membrane Hs cellular component 108 1.04e-23
cell surface Hs cellular component 170 1.70e-42
channel activity Hs molecular function 108 1.04e-23
calcium-activated potassium channel activity Hs molecular function 114 1.11e-25
outward rectifier potassium channel activity Hs molecular function 108 1.04e-23
membrane Hs cellular component 170 1.70e-42
integral component of membrane Hs cellular component 170 1.70e-42
basolateral plasma membrane Hs cellular component 170 1.70e-42
lateral plasma membrane Hs cellular component 170 1.70e-42
protein kinase binding Hs molecular function 170 1.70e-42
protein domain specific binding Hs molecular function 170 1.70e-42
voltage-gated cation channel activity Hs molecular function 108 1.04e-23
lamellipodium Hs cellular component 108 1.04e-23
carbohydrate binding Hs molecular function 170 1.70e-42
cytoplasmic vesicle membrane Hs cellular component 108 1.04e-23
Golgi-associated vesicle membrane Hs cellular component 170 1.70e-42
cytoplasmic vesicle Hs cellular component 108 1.04e-23
motile cilium Hs cellular component 170 1.70e-42
filamentous actin Hs cellular component 108 1.04e-23
sour taste receptor activity Hs molecular function 114 1.11e-25
cation channel complex Hs cellular component 114 1.11e-25
calcium channel complex Hs cellular component 114 1.11e-25
ciliary basal body Hs cellular component 108 1.04e-23
identical protein binding Hs molecular function 114 1.11e-25
protein homodimerization activity Hs molecular function 108 1.04e-23
actinin binding Hs molecular function 108 1.04e-23
cell projection Hs cellular component 170 1.70e-42
intracellular membrane-bounded organelle Hs cellular component 114 1.11e-25
receptor complex Hs cellular component 114 1.11e-25
HLH domain binding Hs molecular function 108 1.04e-23
ion channel binding Hs molecular function 170 1.70e-42
basal cortex Hs cellular component 108 1.04e-23
metal ion binding Hs molecular function 108 1.04e-23
calcium-induced calcium release activity Hs molecular function 108 1.04e-23
ATPase binding Hs molecular function 108 1.04e-23
phosphoprotein binding Hs molecular function 108 1.04e-23
muscle alpha-actinin binding Hs molecular function 114 1.11e-25
alpha-actinin binding Hs molecular function 114 1.11e-25
ciliary membrane Hs cellular component 170 1.70e-42
extracellular exosome Hs cellular component 170 1.70e-42
integral component of cytoplasmic side of endoplasmic reticulum membrane Hs cellular component 108 1.04e-23
integral component of lumenal side of endoplasmic reticulum membrane Hs cellular component 108 1.04e-23
mitotic spindle Hs cellular component 108 1.04e-23
non-motile cilium Hs cellular component 114 1.11e-25

GO (InterProScan)

2 results

GO Term Analysis Type e-value
kidney development PRINTS biological process 1.4E-8
integral component of membrane PRINTS cellular component 1.4E-8