Gene Card
Best human hits
EPS8; EPS8L1; EPS8L2
Species
Unique Gene ID
Boleac.g00005649
Gene Model ID
Boleac.CG.SB_v3.S238.g05649
Location
S238:101397..123968
Transcript Models and Sequences
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
EPS8 | PANTHER | Epidermal growth factor receptor kinase substrate 8 |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
SH3_domain | Pfam | SH3 domain |
PTB | Pfam | Tensin/EPS8 phosphotyrosine-binding domain |
PTB/PI_dom | SMART | PTB/PI domain |
SH3_domain | ProSiteProfiles | SH3 domain |
SH3_domain | SMART | SH3 domain |
EPS8_PTB | CDD | Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain |
SAM/pointed_sf | SUPERFAMILY | Sterile alpha motif/pointed domain superfamily |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
actin binding | Hs | molecular function |
SH3/SH2 adaptor activity | Hs | molecular function |
Rho guanyl-nucleotide exchange factor activity | Hs | molecular function |
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
brush border | Hs | cellular component |
cell cortex | Hs | cellular component |
signal transduction | Hs | biological process |
epidermal growth factor receptor signaling pathway | Hs | biological process |
Rho protein signal transduction | Hs | biological process |
sensory perception of sound | Hs | biological process |
cell proliferation | Hs | biological process |
adult locomotory behavior | Hs | biological process |
regulation of cell shape | Hs | biological process |
positive regulation of signal transduction | Hs | biological process |
exit from mitosis | Hs | biological process |
postsynaptic density | Hs | cellular component |
membrane | Hs | cellular component |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
Rac protein signal transduction | Hs | biological process |
NMDA selective glutamate receptor complex | Hs | cellular component |
cell junction | Hs | cellular component |
growth cone | Hs | cellular component |
Rac guanyl-nucleotide exchange factor activity | Hs | molecular function |
actin cytoskeleton reorganization | Hs | biological process |
vesicle | Hs | cellular component |
stereocilium | Hs | cellular component |
stereocilium bundle | Hs | cellular component |
stereocilium tip | Hs | cellular component |
ruffle membrane | Hs | cellular component |
macromolecular complex | Hs | cellular component |
regulation of Rho protein signal transduction | Hs | biological process |
signaling adaptor activity | Hs | molecular function |
T cell receptor binding | Hs | molecular function |
cell projection | Hs | cellular component |
neuron projection | Hs | cellular component |
synapse | Hs | cellular component |
cadherin binding | Hs | molecular function |
behavioral response to ethanol | Hs | biological process |
Rac GTPase binding | Hs | molecular function |
barbed-end actin filament capping | Hs | biological process |
actin filament bundle assembly | Hs | biological process |
actin crosslink formation | Hs | biological process |
regulation of molecular function | Hs | biological process |
extracellular exosome | Hs | cellular component |
positive regulation of ruffle assembly | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
actin binding | Hs | molecular function | 494 | 2.05e-164 |
SH3/SH2 adaptor activity | Hs | molecular function | 494 | 2.05e-164 |
Rho guanyl-nucleotide exchange factor activity | Hs | molecular function | 427 | 2.26e-139 |
protein binding | Hs | molecular function | 494 | 2.05e-164 |
cytoplasm | Hs | cellular component | 494 | 2.05e-164 |
cytosol | Hs | cellular component | 427 | 2.26e-139 |
plasma membrane | Hs | cellular component | 494 | 2.05e-164 |
brush border | Hs | cellular component | 494 | 2.05e-164 |
cell cortex | Hs | cellular component | 494 | 2.05e-164 |
postsynaptic density | Hs | cellular component | 494 | 2.05e-164 |
membrane | Hs | cellular component | 494 | 2.05e-164 |
kinase activity | Hs | molecular function | 375 | 1.04e-119 |
NMDA selective glutamate receptor complex | Hs | cellular component | 494 | 2.05e-164 |
cell junction | Hs | cellular component | 494 | 2.05e-164 |
growth cone | Hs | cellular component | 494 | 2.05e-164 |
Rac guanyl-nucleotide exchange factor activity | Hs | molecular function | 427 | 2.26e-139 |
vesicle | Hs | cellular component | 494 | 2.05e-164 |
stereocilium | Hs | cellular component | 494 | 2.05e-164 |
stereocilium bundle | Hs | cellular component | 494 | 2.05e-164 |
stereocilium tip | Hs | cellular component | 494 | 2.05e-164 |
ruffle membrane | Hs | cellular component | 494 | 2.05e-164 |
macromolecular complex | Hs | cellular component | 427 | 2.26e-139 |
signaling adaptor activity | Hs | molecular function | 494 | 2.05e-164 |
T cell receptor binding | Hs | molecular function | 375 | 1.04e-119 |
cell projection | Hs | cellular component | 494 | 2.05e-164 |
neuron projection | Hs | cellular component | 494 | 2.05e-164 |
synapse | Hs | cellular component | 494 | 2.05e-164 |
cadherin binding | Hs | molecular function | 427 | 2.26e-139 |
Rac GTPase binding | Hs | molecular function | 494 | 2.05e-164 |
extracellular exosome | Hs | cellular component | 494 | 2.05e-164 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
actin binding | PANTHER | molecular function | 7.3E-210 |
protein binding | Pfam | molecular function | 1.7E-35 |
signaling adaptor activity | PANTHER | molecular function | 7.3E-210 |
barbed-end actin filament capping | PANTHER | biological process | 7.3E-210 |