Gene Card
Best human hits
MFN1; MFN2
Species
Unique Gene ID
Boleac.g00005002
Gene Model ID
Boleac.CG.SB_v3.S214.g05002
Location
S214:11530..17475
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
6 results
| IPR Term | Analysis | Definition |
|---|---|---|
| G_DYNAMIN_dom | ProSiteProfiles | Dynamin-type guanine nucleotide-binding (G) domain |
| P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
| Mitofusin_fam | PANTHER | Mitofusin family |
| Dynamin_SF | Pfam | Dynamin superfamily |
| Fzo/mitofusin_HR2 | Pfam | Fzo/mitofusin HR2 domain |
| Mitofusin-2 | PANTHER | Mitofusin-2 |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
30 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| nucleotide binding | Hs | molecular function |
| GTPase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| GTP binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| mitochondrion | Hs | cellular component |
| mitochondrial outer membrane | Hs | cellular component |
| cytosol | Hs | cellular component |
| protein targeting to mitochondrion | Hs | biological process |
| autophagy | Hs | biological process |
| apoptotic process | Hs | biological process |
| response to unfolded protein | Hs | biological process |
| mitochondrial membrane organization | Hs | biological process |
| blood coagulation | Hs | biological process |
| mitochondrial fusion | Hs | biological process |
| microtubule cytoskeleton | Hs | cellular component |
| membrane | Hs | cellular component |
| integral component of membrane | Hs | cellular component |
| macroautophagy | Hs | biological process |
| hydrolase activity | Hs | molecular function |
| intrinsic component of mitochondrial outer membrane | Hs | cellular component |
| integral component of mitochondrial outer membrane | Hs | cellular component |
| ubiquitin protein ligase binding | Hs | molecular function |
| protein localization to pre-autophagosomal structure | Hs | biological process |
| GTP metabolic process | Hs | biological process |
| negative regulation of Ras protein signal transduction | Hs | biological process |
| camera-type eye morphogenesis | Hs | biological process |
| negative regulation of smooth muscle cell proliferation | Hs | biological process |
| mitochondrion localization | Hs | biological process |
| outer mitochondrial membrane protein complex | Hs | cellular component |
GO (Blast)
16 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 727 | 0.0 |
| GTPase activity | Hs | molecular function | 727 | 0.0 |
| protein binding | Hs | molecular function | 727 | 0.0 |
| GTP binding | Hs | molecular function | 727 | 0.0 |
| cytoplasm | Hs | cellular component | 662 | 0.0 |
| mitochondrion | Hs | cellular component | 727 | 0.0 |
| mitochondrial outer membrane | Hs | cellular component | 727 | 0.0 |
| cytosol | Hs | cellular component | 727 | 0.0 |
| microtubule cytoskeleton | Hs | cellular component | 727 | 0.0 |
| membrane | Hs | cellular component | 727 | 0.0 |
| integral component of membrane | Hs | cellular component | 727 | 0.0 |
| hydrolase activity | Hs | molecular function | 727 | 0.0 |
| intrinsic component of mitochondrial outer membrane | Hs | cellular component | 727 | 0.0 |
| integral component of mitochondrial outer membrane | Hs | cellular component | 662 | 0.0 |
| ubiquitin protein ligase binding | Hs | molecular function | 727 | 0.0 |
| outer mitochondrial membrane protein complex | Hs | cellular component | 662 | 0.0 |
GO (InterProScan)
7 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| GTPase activity | PANTHER | molecular function | 2.1E-256 |
| GTP binding | ProSiteProfiles | molecular function | 45.099 |
| mitochondrion | PANTHER | cellular component | 2.1E-256 |
| mitochondrial outer membrane | Pfam | cellular component | 1.1E-52 |
| mitochondrial fusion | PANTHER | biological process | 2.1E-256 |
| integral component of membrane | PANTHER | cellular component | 2.1E-256 |
| negative regulation of smooth muscle cell proliferation | PANTHER | biological process | 2.1E-256 |
