Aniseed - Gene card

Gene Card

Best human hits

TRAF2; TRAF3; TRAF5

Species

B.leachii

Unique Gene ID

Boleac.g00002180

Gene Model ID

Boleac.CG.SB_v3.S13.g02180

Location

S13:518591..528876

Transcript Models and Sequences

Boleac.CG.SB_v3.S13.g02180.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

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Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term	Analysis	Definition
TRAF-like	SUPERFAMILY	TRAF-like
Znf_TRAF	Pfam	Zinc finger, TRAF-type
Znf_RING	SMART	Zinc finger, RING-type
Znf_RING/FYVE/PHD	Gene3D	Zinc finger, RING/FYVE/PHD-type
MATH/TRAF_dom	ProSiteProfiles	MATH/TRAF domain
TRAF3	PANTHER	TNF receptor-associated factor 3
TRAF-like	Gene3D	TRAF-like
Znf_RING	ProSiteProfiles	Zinc finger, RING-type
TNF_rcpt--assoc_TRAF	PIRSF	TNF receptor-associated factor TRAF
Znf_TRAF	ProSiteProfiles	Zinc finger, TRAF-type
MATH/TRAF_dom	SMART	MATH/TRAF domain
MATH/TRAF_dom	Pfam	MATH/TRAF domain
Znf_RING_CS	ProSitePatterns	Zinc finger, RING-type, conserved site

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

73 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
toll-like receptor signaling pathway	Hs	biological process
immune system process	Hs	biological process
ubiquitin-protein transferase activity	Hs	molecular function
tumor necrosis factor receptor binding	Hs	molecular function
protein binding	Hs	molecular function
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
cell cortex	Hs	cellular component
signal transduction	Hs	biological process
I-kappaB kinase/NF-kappaB signaling	Hs	biological process
activation of NF-kappaB-inducing kinase activity	Hs	biological process
zinc ion binding	Hs	molecular function
cytoplasmic side of plasma membrane	Hs	cellular component
protein ubiquitination	Hs	biological process
protein deubiquitination	Hs	biological process
transferase activity	Hs	molecular function
protein kinase binding	Hs	molecular function
mitogen-activated protein kinase kinase kinase binding	Hs	molecular function
ubiquitin protein ligase binding	Hs	molecular function
thioesterase binding	Hs	molecular function
CD40 receptor complex	Hs	cellular component
identical protein binding	Hs	molecular function
regulation of apoptotic process	Hs	biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
positive regulation of JUN kinase activity	Hs	biological process
metal ion binding	Hs	molecular function
positive regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
positive regulation of NF-kappaB transcription factor activity	Hs	biological process
protein autoubiquitination	Hs	biological process
protein K63-linked ubiquitination	Hs	biological process
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
activation of MAPK activity	Hs	biological process
protein polyubiquitination	Hs	biological process
ossification	Hs	biological process
neural tube closure	Hs	biological process
MyD88-dependent toll-like receptor signaling pathway	Hs	biological process
nucleus	Hs	cellular component
lipid droplet	Hs	cellular component
plasma membrane	Hs	cellular component
immune response	Hs	biological process
cellular response to DNA damage stimulus	Hs	biological process
JNK cascade	Hs	biological process
animal organ morphogenesis	Hs	biological process
endosome membrane	Hs	cellular component
cytokine-mediated signaling pathway	Hs	biological process
antigen processing and presentation of exogenous peptide antigen via MHC class II	Hs	biological process
osteoclast differentiation	Hs	biological process
membrane protein intracellular domain proteolysis	Hs	biological process
positive regulation of protein ubiquitination	Hs	biological process
ubiquitin conjugating enzyme binding	Hs	molecular function
activation of protein kinase activity	Hs	biological process
macromolecular complex	Hs	cellular component
toll-like receptor 9 signaling pathway	Hs	biological process
Fc-epsilon receptor signaling pathway	Hs	biological process
T-helper 1 type immune response	Hs	biological process
histone deacetylase binding	Hs	molecular function
myeloid dendritic cell differentiation	Hs	biological process
positive regulation of apoptotic process	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
protein kinase B binding	Hs	molecular function
positive regulation of interleukin-6 biosynthetic process	Hs	biological process
bone resorption	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
bone remodeling	Hs	biological process
protein N-terminus binding	Hs	molecular function
cell development	Hs	biological process
perinuclear region of cytoplasm	Hs	cellular component
T cell receptor signaling pathway	Hs	biological process
ubiquitin protein ligase activity	Hs	molecular function
interleukin-1-mediated signaling pathway	Hs	biological process
cellular response to lipopolysaccharide	Hs	biological process

GO (Blast)

34 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
ubiquitin ligase complex	Hs	cellular component	197	1.93e-56
ubiquitin-protein transferase activity	Hs	molecular function	203	3.97e-58
signal transducer activity	Hs	molecular function	203	3.97e-58
receptor binding	Hs	molecular function	197	1.93e-56
tumor necrosis factor receptor binding	Hs	molecular function	203	3.97e-58
CD40 receptor binding	Hs	molecular function	197	1.93e-56
protein binding	Hs	molecular function	203	3.97e-58
intracellular	Hs	cellular component	197	1.93e-56
nucleoplasm	Hs	cellular component	197	1.93e-56
cytoplasm	Hs	cellular component	203	3.97e-58
mitochondrion	Hs	cellular component	203	3.97e-58
endosome	Hs	cellular component	203	3.97e-58
centrosome	Hs	cellular component	195	4.13e-55
cytosol	Hs	cellular component	203	3.97e-58
cell cortex	Hs	cellular component	197	1.93e-56
zinc ion binding	Hs	molecular function	203	3.97e-58
lipid binding	Hs	molecular function	197	1.93e-56
cytoplasmic side of plasma membrane	Hs	cellular component	203	3.97e-58
vesicle membrane	Hs	cellular component	197	1.93e-56
transferase activity	Hs	molecular function	203	3.97e-58
enzyme binding	Hs	molecular function	197	1.93e-56
protein kinase binding	Hs	molecular function	203	3.97e-58
protein phosphatase binding	Hs	molecular function	203	3.97e-58
mitogen-activated protein kinase kinase kinase binding	Hs	molecular function	197	1.93e-56
ubiquitin protein ligase binding	Hs	molecular function	203	3.97e-58
thioesterase binding	Hs	molecular function	203	3.97e-58
CD40 receptor complex	Hs	cellular component	203	3.97e-58
identical protein binding	Hs	molecular function	197	1.93e-56
membrane raft	Hs	cellular component	197	1.93e-56
sphingolipid binding	Hs	molecular function	197	1.93e-56
metal ion binding	Hs	molecular function	203	3.97e-58
TRAF2-GSTP1 complex	Hs	cellular component	197	1.93e-56
AIP1-IRE1 complex	Hs	cellular component	197	1.93e-56
IRE1-TRAF2-ASK1 complex	Hs	cellular component	197	1.93e-56

GO (InterProScan)

11 results

GO Term	Analysis	Type	e-value
regulation of cytokine production	PANTHER	biological process	1.7E-82
tumor necrosis factor receptor binding	PANTHER	molecular function	1.7E-82
protein binding	Gene3D	molecular function	6.8E-59
signal transduction	PIRSF	biological process	3.2E-116
Toll signaling pathway	PANTHER	biological process	1.7E-82
zinc ion binding	PIRSF	molecular function	3.2E-116
negative regulation of NF-kappaB transcription factor activity	PANTHER	biological process	1.7E-82
tumor necrosis factor-mediated signaling pathway	PANTHER	biological process	1.7E-82
regulation of apoptotic process	PIRSF	biological process	3.2E-116
innate immune response	PANTHER	biological process	1.7E-82
regulation of defense response to virus	PANTHER	biological process	1.7E-82