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GENE CARD

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Gene Card

Best human hits

SIRT2; SIRT3

Species

B.leachii

Unique Gene ID

Boleac.g00001263

Gene Model ID

Boleac.CG.SB_v3.S1138.g01263

Location

S1138:2330..5895

Transcript Models and Sequences

  Boleac.CG.SB_v3.S1138.g01263.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
DHS-like_NAD/FAD-binding_dom SUPERFAMILY DHS-like NAD/FAD-binding domain superfamily
Sirtuin_class_I PIRSF Sirtuin, class I
Ssirtuin_cat_dom ProSiteProfiles Sirtuin family, catalytic core domain
Sirtuin Pfam Sirtuin family
Sirtuin_cat_small_dom_sf Gene3D Sirtuin, catalytic core small domain superfamily

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
NAD+ ADP-ribosyltransferase activity Hs molecular function
protein binding Hs molecular function
mitochondrion Hs cellular component
mitochondrial matrix Hs cellular component
protein ADP-ribosylation Hs biological process
protein deacetylation Hs biological process
mitochondrion organization Hs biological process
aging Hs biological process
zinc ion binding Hs molecular function
aerobic respiration Hs biological process
histone deacetylation Hs biological process
hydrolase activity Hs molecular function
NAD-dependent histone deacetylase activity Hs molecular function
enzyme binding Hs molecular function
positive regulation of insulin secretion Hs biological process
macromolecular complex Hs cellular component
NAD-dependent protein deacetylase activity Hs molecular function
sequence-specific DNA binding Hs molecular function
metal ion binding Hs molecular function
negative regulation of ERK1 and ERK2 cascade Hs biological process
NAD+ binding Hs molecular function
negative regulation of reactive oxygen species metabolic process Hs biological process

GO (Blast)

52 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
chromosome, telomeric region Hs cellular component 256 1.91e-82
chromatin binding Hs molecular function 256 1.91e-82
NAD+ ADP-ribosyltransferase activity Hs molecular function 313 1.14e-104
histone deacetylase activity Hs molecular function 256 1.91e-82
protein binding Hs molecular function 313 1.14e-104
nucleus Hs cellular component 256 1.91e-82
chromatin silencing complex Hs cellular component 256 1.91e-82
chromosome Hs cellular component 256 1.91e-82
nuclear heterochromatin Hs cellular component 256 1.91e-82
nucleolus Hs cellular component 256 1.91e-82
cytoplasm Hs cellular component 256 1.91e-82
mitochondrion Hs cellular component 313 1.14e-104
mitochondrial matrix Hs cellular component 313 1.14e-104
centrosome Hs cellular component 256 1.91e-82
centriole Hs cellular component 256 1.91e-82
microtubule organizing center Hs cellular component 256 1.91e-82
spindle Hs cellular component 256 1.91e-82
cytosol Hs cellular component 256 1.91e-82
cytoskeleton Hs cellular component 256 1.91e-82
microtubule Hs cellular component 256 1.91e-82
plasma membrane Hs cellular component 256 1.91e-82
transcription factor binding Hs molecular function 256 1.91e-82
zinc ion binding Hs molecular function 313 1.14e-104
membrane Hs cellular component 256 1.91e-82
hydrolase activity Hs molecular function 313 1.14e-104
NAD-dependent histone deacetylase activity Hs molecular function 313 1.14e-104
enzyme binding Hs molecular function 313 1.14e-104
growth cone Hs cellular component 256 1.91e-82
midbody Hs cellular component 256 1.91e-82
macromolecular complex Hs cellular component 313 1.14e-104
paranodal junction Hs cellular component 256 1.91e-82
paranode region of axon Hs cellular component 256 1.91e-82
protein deacetylase activity Hs molecular function 256 1.91e-82
NAD-dependent protein deacetylase activity Hs molecular function 313 1.14e-104
histone acetyltransferase binding Hs molecular function 256 1.91e-82
histone deacetylase binding Hs molecular function 256 1.91e-82
tubulin deacetylase activity Hs molecular function 256 1.91e-82
cell projection Hs cellular component 256 1.91e-82
ubiquitin binding Hs molecular function 256 1.91e-82
perikaryon Hs cellular component 256 1.91e-82
myelin sheath Hs cellular component 256 1.91e-82
lateral loop Hs cellular component 256 1.91e-82
Schmidt-Lanterman incisure Hs cellular component 256 1.91e-82
sequence-specific DNA binding Hs molecular function 313 1.14e-104
juxtaparanode region of axon Hs cellular component 256 1.91e-82
metal ion binding Hs molecular function 313 1.14e-104
NAD-dependent histone deacetylase activity (H4-K16 specific) Hs molecular function 256 1.91e-82
perinuclear region of cytoplasm Hs cellular component 256 1.91e-82
NAD+ binding Hs molecular function 313 1.14e-104
mitotic spindle Hs cellular component 256 1.91e-82
meiotic spindle Hs cellular component 256 1.91e-82
glial cell projection Hs cellular component 256 1.91e-82

GO (InterProScan)

3 results

GO Term Analysis Type e-value
zinc ion binding PIRSF molecular function 5.6E-116
NAD-dependent histone deacetylase activity PIRSF molecular function 5.6E-116
NAD+ binding Pfam molecular function 2.6E-50