IPR Term	Analysis	Definition
ARM-like	Gene3D	Armadillo-like helical
Armadillo	ProSiteProfiles	Armadillo
Armadillo	Pfam	Armadillo
ARM-type_fold	SUPERFAMILY	Armadillo-type fold
Armadillo	SMART	Armadillo
Beta-catenin	PRINTS	Beta-catenin

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
cell morphogenesis involved in differentiation	Orthology	biological process
vasculature development	Orthology	biological process
chromatin binding	Orthology	molecular function
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
transcription coactivator activity	Orthology	molecular function
signal transducer activity	Orthology	molecular function
structural molecule activity	Orthology	molecular function
binding	Orthology	molecular function
protein binding	Orthology	molecular function
extracellular region	Orthology	cellular component
intracellular	Orthology	cellular component
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
centrosome	Orthology	cellular component
microtubule organizing center	Orthology	cellular component
cytosol	Orthology	cellular component
cytoskeleton	Orthology	cellular component
plasma membrane	Orthology	cellular component
adherens junction	Orthology	cellular component
focal adhesion	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription from RNA polymerase II promoter	Orthology	biological process
cell adhesion	Orthology	biological process
signal transduction	Orthology	biological process
chemical synaptic transmission	Orthology	biological process
nervous system development	Orthology	biological process
heart development	Orthology	biological process
protein C-terminus binding	Orthology	molecular function
transcription factor binding	Orthology	molecular function
cell proliferation	Orthology	biological process
positive regulation of cell proliferation	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
cellular process	Orthology	biological process
regulation of gene expression	Orthology	biological process
positive regulation of gene expression	Orthology	biological process
negative regulation of gene expression	Orthology	biological process
membrane	Orthology	cellular component
basolateral plasma membrane	Orthology	cellular component
cell migration	Orthology	biological process
enzyme binding	Orthology	molecular function
kinase binding	Orthology	molecular function
protein kinase binding	Orthology	molecular function
lamellipodium	Orthology	cellular component
cell junction	Orthology	cellular component
cell differentiation	Orthology	biological process
neuron differentiation	Orthology	biological process
cell projection membrane	Orthology	cellular component
macromolecular complex	Orthology	cellular component
cellular protein localization	Orthology	biological process
regulation of cell proliferation	Orthology	biological process
protein homodimerization activity	Orthology	molecular function
regulation of apoptotic process	Orthology	biological process
cell projection	Blast	cellular component
positive regulation of apoptotic process	Orthology	biological process
apical part of cell	Orthology	cellular component
synapse	Orthology	cellular component
negative regulation of transcription, DNA-templated	Orthology	biological process
positive regulation of transcription, DNA-templated	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
protein heterodimerization activity	Orthology	molecular function
perinuclear region of cytoplasm	Orthology	cellular component
animal organ development	Orthology	biological process
cell adhesion molecule binding	Orthology	molecular function
negative regulation of cell death	Orthology	biological process
extracellular exosome	Orthology	cellular component
cell periphery	Orthology	cellular component
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
multicellular organism development	Orthology	biological process
cytoskeletal part	Orthology	cellular component
microtubule cytoskeleton	Orthology	cellular component
system development	Orthology	biological process
angiogenesis	Orthology	biological process
blood vessel morphogenesis	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
anatomical structure formation involved in morphogenesis	Orthology	biological process
generation of neurons	Orthology	biological process
cell development	Orthology	biological process
cell division	Orthology	biological process
intracellular part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
nuclear lumen	Orthology	cellular component
cytoplasmic part	Orthology	cellular component
organelle organization	Orthology	biological process
cell	Orthology	cellular component
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
anatomical structure development	Orthology	biological process
neurogenesis	Orthology	biological process
plasma membrane part	Orthology	cellular component
plasma membrane region	Orthology	cellular component
membrane raft	Orthology	cellular component
developmental process	Orthology	biological process
central nervous system development	Orthology	biological process
organelle part	Orthology	cellular component
anchoring junction	Orthology	cellular component
immune system process	Orthology	biological process
receptor binding	Orthology	molecular function
response to lipid	Orthology	biological process
cellular response to organic substance	Orthology	biological process
reproductive process	Orthology	biological process
brain development	Orthology	biological process
microtubule-based process	Orthology	biological process
DNA metabolic process	Orthology	biological process
transferase activity, transferring phosphorus-containing groups	Orthology	molecular function
protein modification by small protein conjugation	Orthology	biological process
cellular component organization	Orthology	biological process
intracellular organelle part	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
endomembrane system	Orthology	cellular component
intracellular organelle lumen	Orthology	cellular component
intracellular protein transport	Orthology	biological process
establishment of protein localization to organelle	Orthology	biological process
intracellular signal transduction	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
proteolysis	Orthology	biological process
protein phosphorylation	Orthology	biological process
nuclear part	Orthology	cellular component
intracellular transport	Orthology	biological process
gamete generation	Orthology	biological process
protein oligomerization	Orthology	biological process
cellular protein modification process	Orthology	biological process
membrane organization	Orthology	biological process
transferase activity	Orthology	molecular function
programmed cell death	Orthology	biological process
protein localization to membrane	Orthology	biological process
signaling	Orthology	biological process
cell communication	Orthology	biological process
cellular response to stress	Orthology	biological process
response to oxidative stress	Orthology	biological process
neuron projection morphogenesis	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
negative regulation of apoptotic process	Orthology	biological process
organelle	Blast	cellular component
cell projection part	Blast	cellular component
microtubule	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
embryonic axis specification	Hs	biological process
cell morphogenesis involved in differentiation	Hs	biological process
spindle pole	Hs	cellular component
RNA polymerase II transcription factor binding	Hs	molecular function
RNA polymerase II activating transcription factor binding	Hs	molecular function
RNA polymerase II transcription coactivator activity	Hs	molecular function
skeletal system development	Hs	biological process
cornified envelope	Hs	cellular component
branching involved in blood vessel morphogenesis	Hs	biological process
vasculogenesis	Hs	biological process
branching involved in ureteric bud morphogenesis	Hs	biological process
gastrulation with mouth forming second	Hs	biological process
endoderm formation	Hs	biological process
cell fate specification	Hs	biological process
cell fate determination	Hs	biological process
neuron migration	Hs	biological process
kidney development	Hs	biological process
epithelial to mesenchymal transition	Hs	biological process
neural plate development	Hs	biological process
vasculature development	Hs	biological process
positive regulation of cell-matrix adhesion	Hs	biological process
positive regulation of neuroblast proliferation	Hs	biological process
lens morphogenesis in camera-type eye	Hs	biological process
desmosome assembly	Hs	biological process
chromatin binding	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcription coactivator activity	Hs	molecular function
signal transducer activity	Hs	molecular function
structural molecule activity	Hs	molecular function
structural constituent of cell wall	Hs	molecular function
binding	Hs	molecular function
protein binding	Hs	molecular function
extracellular region	Hs	cellular component
intracellular	Hs	cellular component
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
transcription factor complex	Hs	cellular component
nuclear euchromatin	Hs	cellular component
cytoplasm	Hs	cellular component
centrosome	Hs	cellular component
microtubule organizing center	Hs	cellular component
cytosol	Hs	cellular component
cytoskeleton	Hs	cellular component
intermediate filament	Hs	cellular component
plasma membrane	Hs	cellular component
cell-cell junction	Hs	cellular component
adherens junction	Hs	cellular component
cell-cell adherens junction	Hs	cellular component
zonula adherens	Hs	cellular component
fascia adherens	Hs	cellular component
bicellular tight junction	Hs	cellular component
focal adhesion	Hs	cellular component
cell cortex	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
transcription from RNA polymerase II promoter	Hs	biological process
cytoskeletal anchoring at plasma membrane	Hs	biological process
cell adhesion	Hs	biological process
cell-matrix adhesion	Hs	biological process
signal transduction	Hs	biological process
Wnt signaling pathway, calcium modulating pathway	Hs	biological process
chemical synaptic transmission	Hs	biological process
ectoderm development	Hs	biological process
nervous system development	Hs	biological process
glial cell fate determination	Hs	biological process
heart development	Hs	biological process
protein C-terminus binding	Hs	molecular function
transcription factor binding	Hs	molecular function
cell proliferation	Hs	biological process
positive regulation of cell proliferation	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
cytoplasmic side of plasma membrane	Hs	cellular component
anterior/posterior axis specification	Hs	biological process
dorsal/ventral axis specification	Hs	biological process
dorsal/ventral pattern formation	Hs	biological process
proximal/distal pattern formation	Hs	biological process
cellular process	Hs	biological process
regulation of gene expression	Hs	biological process
positive regulation of gene expression	Hs	biological process
negative regulation of gene expression	Hs	biological process
positive regulation of epithelial to mesenchymal transition	Hs	biological process
intercalated disc	Hs	cellular component
actin cytoskeleton	Hs	cellular component
membrane	Hs	cellular component
Wnt signaling pathway	Hs	biological process
basolateral plasma membrane	Hs	cellular component
apicolateral plasma membrane	Hs	cellular component
lateral plasma membrane	Hs	cellular component
morphogenesis of embryonic epithelium	Hs	biological process
catenin complex	Hs	cellular component
cell migration	Hs	biological process
negative regulation of angiogenesis	Hs	biological process
flotillin complex	Hs	cellular component
stem cell population maintenance	Hs	biological process
enzyme binding	Hs	molecular function
kinase binding	Hs	molecular function
protein kinase binding	Hs	molecular function
protein phosphatase binding	Hs	molecular function
central nervous system vasculogenesis	Hs	biological process
Z disc	Hs	cellular component
lamellipodium	Hs	cellular component
cell junction	Hs	cellular component
desmosome	Hs	cellular component
hemopoiesis	Hs	biological process
cell differentiation	Hs	biological process
neuron differentiation	Hs	biological process
T cell differentiation	Hs	biological process
osteoclast differentiation	Hs	biological process
lung development	Hs	biological process
estrogen receptor binding	Hs	molecular function
androgen receptor signaling pathway	Hs	biological process
male genitalia development	Hs	biological process
regulation of epithelial cell differentiation	Hs	biological process
positive regulation of epithelial cell differentiation	Hs	biological process
beta-catenin destruction complex	Hs	cellular component
forebrain development	Hs	biological process
midbrain development	Hs	biological process
hindbrain development	Hs	biological process
regulation of centriole-centriole cohesion	Hs	biological process
pancreas development	Hs	biological process
cell projection membrane	Hs	cellular component
microvillus membrane	Hs	cellular component
regulation of myelination	Hs	biological process
positive regulation of telomere maintenance via telomerase	Hs	biological process
response to estradiol	Hs	biological process
positive regulation of type I interferon production	Hs	biological process
macromolecular complex	Hs	cellular component
protein-DNA complex	Hs	cellular component
T cell differentiation in thymus	Hs	biological process
negative regulation of protein sumoylation	Hs	biological process
adherens junction organization	Hs	biological process
adherens junction assembly	Hs	biological process
protein localization to cell surface	Hs	biological process
cellular protein localization	Hs	biological process
Scrib-APC-beta-catenin complex	Hs	cellular component
embryonic heart tube development	Hs	biological process
embryonic hindlimb morphogenesis	Hs	biological process
nuclear hormone receptor binding	Hs	molecular function
hair cell differentiation	Hs	biological process
specific granule lumen	Hs	cellular component
regulation of cell proliferation	Hs	biological process
regulation of T cell proliferation	Hs	biological process
positive regulation of protein import into nucleus	Hs	biological process
response to drug	Hs	biological process
protein homodimerization activity	Hs	molecular function
regulation of apoptotic process	Hs	biological process
positive regulation of apoptotic process	Hs	biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
proteasome-mediated ubiquitin-dependent protein catabolic process	Hs	biological process
apical junction complex	Hs	cellular component
positive regulation of MAPK cascade	Hs	biological process
positive regulation of neuron apoptotic process	Hs	biological process
negative regulation of blood vessel endothelial cell migration	Hs	biological process
skin development	Hs	biological process
ion channel binding	Hs	molecular function
nuclear transcription factor complex	Hs	cellular component
apical part of cell	Hs	cellular component
synapse	Hs	cellular component
alpha-catenin binding	Hs	molecular function
cadherin binding	Hs	molecular function
bone resorption	Hs	biological process
regulation of cell differentiation	Hs	biological process
negative regulation of cell differentiation	Hs	biological process
positive regulation of endothelial cell differentiation	Hs	biological process
regulation of osteoblast differentiation	Hs	biological process
positive regulation of osteoblast differentiation	Hs	biological process
regulation of osteoclast differentiation	Hs	biological process
positive regulation of fibroblast growth factor receptor signaling pathway	Hs	biological process
regulation of angiogenesis	Hs	biological process
positive regulation of angiogenesis	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
SMAD binding	Hs	molecular function
protein heterodimerization activity	Hs	molecular function
chromatin-mediated maintenance of transcription	Hs	biological process
perinuclear region of cytoplasm	Hs	cellular component
synaptic vesicle transport	Hs	biological process
animal organ development	Hs	biological process
thymus development	Hs	biological process
oocyte development	Hs	biological process
embryonic foregut morphogenesis	Hs	biological process
androgen receptor binding	Hs	molecular function
regulation of neurogenesis	Hs	biological process
synapse organization	Hs	biological process
cell adhesion molecule binding	Hs	molecular function
detection of mechanical stimulus	Hs	biological process
positive regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
smooth muscle cell differentiation	Hs	biological process
protein heterooligomerization	Hs	biological process
positive regulation of histone H3-K4 methylation	Hs	biological process
canonical Wnt signaling pathway	Hs	biological process
limb development	Hs	biological process
trachea morphogenesis	Hs	biological process
negative regulation of cell death	Hs	biological process
sympathetic ganglion development	Hs	biological process
cranial ganglion development	Hs	biological process
extracellular exosome	Hs	cellular component
cornification	Hs	biological process
beta-catenin-TCF7L2 complex	Hs	cellular component
I-SMAD binding	Hs	molecular function
repressing transcription factor binding	Hs	molecular function
gamma-catenin-TCF7L2 complex	Hs	cellular component
cell periphery	Hs	cellular component
renal system development	Hs	biological process
protein localization to plasma membrane	Hs	biological process
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	Hs	molecular function
regulation of heart rate by cardiac conduction	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process
disordered domain specific binding	Hs	molecular function
cell-cell adhesion	Hs	biological process
negative regulation of neuron death	Hs	biological process
negative regulation of oxidative stress-induced neuron death	Hs	biological process
ficolin-1-rich granule lumen	Hs	cellular component
cranial skeletal system development	Hs	biological process
neuron projection extension	Hs	biological process
embryonic brain development	Hs	biological process
dorsal root ganglion development	Hs	biological process
beta-catenin-TCF complex	Hs	cellular component
Wnt signalosome	Hs	cellular component
regulation of protein localization to cell surface	Hs	biological process
negative regulation of apoptotic signaling pathway	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
spindle pole	Hs	cellular component	986	0.0
RNA polymerase II transcription factor binding	Hs	molecular function	986	0.0
RNA polymerase II activating transcription factor binding	Hs	molecular function	986	0.0
RNA polymerase II transcription coactivator activity	Hs	molecular function	986	0.0
cornified envelope	Hs	cellular component	867	0.0
chromatin binding	Hs	molecular function	986	0.0
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	986	0.0
transcription coactivator activity	Hs	molecular function	986	0.0
signal transducer activity	Hs	molecular function	986	0.0
structural molecule activity	Hs	molecular function	867	0.0
structural constituent of cell wall	Hs	molecular function	867	0.0
binding	Hs	molecular function	986	0.0
protein binding	Hs	molecular function	986	0.0
extracellular region	Hs	cellular component	867	0.0
intracellular	Hs	cellular component	986	0.0
nucleus	Hs	cellular component	986	0.0
nucleoplasm	Hs	cellular component	986	0.0
transcription factor complex	Hs	cellular component	986	0.0
nuclear euchromatin	Hs	cellular component	986	0.0
cytoplasm	Hs	cellular component	986	0.0
centrosome	Hs	cellular component	986	0.0
microtubule organizing center	Hs	cellular component	986	0.0
cytosol	Hs	cellular component	986	0.0
cytoskeleton	Hs	cellular component	986	0.0
intermediate filament	Hs	cellular component	867	0.0
plasma membrane	Hs	cellular component	986	0.0
cell-cell junction	Hs	cellular component	986	0.0
adherens junction	Hs	cellular component	986	0.0
cell-cell adherens junction	Hs	cellular component	986	0.0
zonula adherens	Hs	cellular component	867	0.0
fascia adherens	Hs	cellular component	986	0.0
bicellular tight junction	Hs	cellular component	986	0.0
focal adhesion	Hs	cellular component	986	0.0
cilium	Hs	cellular component	62.8	5.59e-10
axoneme	Hs	cellular component	62.8	5.59e-10
cell cortex	Hs	cellular component	986	0.0
protein C-terminus binding	Hs	molecular function	986	0.0
transcription factor binding	Hs	molecular function	986	0.0
cytoplasmic side of plasma membrane	Hs	cellular component	867	0.0
intercalated disc	Hs	cellular component	986	0.0
actin cytoskeleton	Hs	cellular component	867	0.0
membrane	Hs	cellular component	986	0.0
basolateral plasma membrane	Hs	cellular component	986	0.0
apicolateral plasma membrane	Hs	cellular component	867	0.0
lateral plasma membrane	Hs	cellular component	986	0.0
catenin complex	Hs	cellular component	986	0.0
flotillin complex	Hs	cellular component	986	0.0
enzyme binding	Hs	molecular function	986	0.0
kinase binding	Hs	molecular function	986	0.0
protein kinase binding	Hs	molecular function	986	0.0
protein phosphatase binding	Hs	molecular function	986	0.0
Z disc	Hs	cellular component	986	0.0
lamellipodium	Hs	cellular component	986	0.0
cell junction	Hs	cellular component	986	0.0
desmosome	Hs	cellular component	867	0.0
estrogen receptor binding	Hs	molecular function	986	0.0
beta-catenin destruction complex	Hs	cellular component	986	0.0
cell projection membrane	Hs	cellular component	986	0.0
microvillus membrane	Hs	cellular component	986	0.0
macromolecular complex	Hs	cellular component	986	0.0
protein-DNA complex	Hs	cellular component	986	0.0
Scrib-APC-beta-catenin complex	Hs	cellular component	986	0.0
nuclear hormone receptor binding	Hs	molecular function	986	0.0
specific granule lumen	Hs	cellular component	867	0.0
protein homodimerization activity	Hs	molecular function	867	0.0
cell projection	Hs	cellular component	62.8	5.59e-10
apical junction complex	Hs	cellular component	986	0.0
ion channel binding	Hs	molecular function	986	0.0
nuclear transcription factor complex	Hs	cellular component	986	0.0
apical part of cell	Hs	cellular component	986	0.0
synapse	Hs	cellular component	986	0.0
alpha-catenin binding	Hs	molecular function	986	0.0
cadherin binding	Hs	molecular function	986	0.0
SMAD binding	Hs	molecular function	986	0.0
protein heterodimerization activity	Hs	molecular function	986	0.0
perinuclear region of cytoplasm	Hs	cellular component	986	0.0
androgen receptor binding	Hs	molecular function	986	0.0
cell adhesion molecule binding	Hs	molecular function	867	0.0
extracellular exosome	Hs	cellular component	986	0.0
beta-catenin-TCF7L2 complex	Hs	cellular component	986	0.0
I-SMAD binding	Hs	molecular function	986	0.0
repressing transcription factor binding	Hs	molecular function	986	0.0
gamma-catenin-TCF7L2 complex	Hs	cellular component	867	0.0
cell periphery	Hs	cellular component	986	0.0
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	Hs	molecular function	867	0.0
ciliary base	Hs	cellular component	62.8	5.59e-10
disordered domain specific binding	Hs	molecular function	986	0.0
ficolin-1-rich granule lumen	Hs	cellular component	867	0.0
beta-catenin-TCF complex	Hs	cellular component	986	0.0
Wnt signalosome	Hs	cellular component	986	0.0

GO Term	Analysis	Type	e-value
signal transducer activity	PRINTS	molecular function	1.6E-101
binding	SUPERFAMILY	molecular function	2.8E-82
protein binding	Pfam	molecular function	9.6E-7
cell adhesion	PRINTS	biological process	1.6E-101
adherens junction assembly	PRINTS	biological process	1.6E-101