IPR Term	Analysis	Definition
Tyr_kinase_AS	ProSitePatterns	Tyrosine-protein kinase, active site
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
Ser-Thr/Tyr_kinase_cat_dom	Pfam	Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyr_kinase_cat_dom	SMART	Tyrosine-protein kinase, catalytic domain
Ser-Thr/Tyr_kinase_cat_dom	PRINTS	Serine-threonine/tyrosine-protein kinase, catalytic domain
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
protein kinase activity	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
cytoplasm	Orthology	cellular component
endosome	Blast	cellular component
early endosome	Blast	cellular component
cytosol	Blast	cellular component
microtubule	Orthology	cellular component
plasma membrane	Orthology	cellular component
integral component of plasma membrane	Orthology	cellular component
protein phosphorylation	Orthology	biological process
signal transduction	Orthology	biological process
multicellular organism development	Orthology	biological process
sensory perception of sound	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
cell surface	Orthology	cellular component
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
transferase activity	Orthology	molecular function
cell differentiation	Orthology	biological process
axon	Orthology	cellular component
protein homodimerization activity	Blast	molecular function
cell projection	Orthology	cellular component
neuronal cell body	Orthology	cellular component
postsynaptic membrane	Blast	cellular component
positive regulation of transcription, DNA-templated	Orthology	biological process
metal ion binding	Orthology	molecular function
regulation of canonical Wnt signaling pathway	Orthology	biological process
negative regulation of canonical Wnt signaling pathway	Orthology	biological process
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
system development	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
cytoskeletal part	Orthology	cellular component
anatomical structure formation involved in morphogenesis	Orthology	biological process
transmembrane signaling receptor activity	Orthology	molecular function
receptor binding	Orthology	molecular function
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
cellular response to stress	Orthology	biological process
intracellular signal transduction	Orthology	biological process
cell development	Orthology	biological process
neurogenesis	Orthology	biological process
central nervous system development	Orthology	biological process
cell migration	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
cellular response to organic substance	Orthology	biological process
reproductive process	Orthology	biological process
whole membrane	Orthology	cellular component
intracellular organelle part	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
macromolecular complex	Orthology	cellular component
positive regulation of catalytic activity	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
cell projection part	Orthology	cellular component
synapse part	Orthology	cellular component
chemical synaptic transmission	Orthology	biological process
signaling receptor activity	Orthology	molecular function
immune system process	Orthology	biological process
organelle	Blast	cellular component
postsynapse	Blast	cellular component
neuron part	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
skeletal system development	Hs	biological process
cartilage condensation	Hs	biological process
stress fiber	Hs	cellular component
somitogenesis	Hs	biological process
protein kinase activity	Hs	molecular function
protein tyrosine kinase activity	Hs	molecular function
transmembrane receptor protein tyrosine kinase activity	Hs	molecular function
frizzled binding	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
cytoplasm	Hs	cellular component
microtubule	Hs	cellular component
plasma membrane	Hs	cellular component
integral component of plasma membrane	Hs	cellular component
protein phosphorylation	Hs	biological process
signal transduction	Hs	biological process
transmembrane receptor protein tyrosine kinase signaling pathway	Hs	biological process
Wnt signaling pathway, calcium modulating pathway	Hs	biological process
smoothened signaling pathway	Hs	biological process
JNK cascade	Hs	biological process
multicellular organism development	Hs	biological process
sensory perception of sound	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
cell surface	Hs	cellular component
astrocyte development	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
Wnt signaling pathway	Hs	biological process
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
transferase activity	Hs	molecular function
Wnt-protein binding	Hs	molecular function
peptidyl-tyrosine phosphorylation	Hs	biological process
cell differentiation	Hs	biological process
bone mineralization	Hs	biological process
positive regulation of cell migration	Hs	biological process
axon	Hs	cellular component
dendrite	Hs	cellular component
BMP signaling pathway	Hs	biological process
embryonic genitalia morphogenesis	Hs	biological process
male genitalia development	Hs	biological process
clathrin-coated endocytic vesicle membrane	Hs	cellular component
inner ear morphogenesis	Hs	biological process
Wnt-activated receptor activity	Hs	molecular function
cell projection	Hs	cellular component
neuronal cell body	Hs	cellular component
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
receptor complex	Hs	cellular component
positive regulation of JUN kinase activity	Hs	biological process
axon terminus	Hs	cellular component
cell fate commitment	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
metal ion binding	Hs	molecular function
inner ear development	Hs	biological process
positive regulation of NF-kappaB transcription factor activity	Hs	biological process
positive regulation of synaptic transmission, glutamatergic	Hs	biological process
Wnt signaling pathway, planar cell polarity pathway	Hs	biological process
SMAD protein signal transduction	Hs	biological process
regulation of canonical Wnt signaling pathway	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	Hs	molecular function
macrophage migration	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	178	8.08e-48
stress fiber	Hs	cellular component	178	8.08e-48
protein kinase activity	Hs	molecular function	178	8.08e-48
protein tyrosine kinase activity	Hs	molecular function	173	4.27e-46
transmembrane receptor protein tyrosine kinase activity	Hs	molecular function	178	8.08e-48
neurotrophin receptor activity	Hs	molecular function	138	1.74e-34
frizzled binding	Hs	molecular function	173	4.27e-46
protein binding	Hs	molecular function	178	8.08e-48
ATP binding	Hs	molecular function	178	8.08e-48
cytoplasm	Hs	cellular component	178	8.08e-48
endosome	Hs	cellular component	138	1.74e-34
early endosome	Hs	cellular component	138	1.74e-34
cytosol	Hs	cellular component	138	1.74e-34
microtubule	Hs	cellular component	173	4.27e-46
plasma membrane	Hs	cellular component	178	8.08e-48
integral component of plasma membrane	Hs	cellular component	178	8.08e-48
cell surface	Hs	cellular component	178	8.08e-48
endosome membrane	Hs	cellular component	138	1.74e-34
postsynaptic density	Hs	cellular component	138	1.74e-34
membrane	Hs	cellular component	178	8.08e-48
integral component of membrane	Hs	cellular component	178	8.08e-48
kinase activity	Hs	molecular function	178	8.08e-48
transferase activity	Hs	molecular function	178	8.08e-48
Wnt-protein binding	Hs	molecular function	178	8.08e-48
axon	Hs	cellular component	178	8.08e-48
dendrite	Hs	cellular component	173	4.27e-46
clathrin-coated endocytic vesicle membrane	Hs	cellular component	173	4.27e-46
early endosome membrane	Hs	cellular component	138	1.74e-34
protein homodimerization activity	Hs	molecular function	138	1.74e-34
Wnt-activated receptor activity	Hs	molecular function	178	8.08e-48
cell projection	Hs	cellular component	178	8.08e-48
neuronal cell body	Hs	cellular component	173	4.27e-46
neurotrophin binding	Hs	molecular function	138	1.74e-34
terminal bouton	Hs	cellular component	138	1.74e-34
receptor complex	Hs	cellular component	178	8.08e-48
axon terminus	Hs	cellular component	178	8.08e-48
postsynaptic membrane	Hs	cellular component	138	1.74e-34
metal ion binding	Hs	molecular function	173	4.27e-46
brain-derived neurotrophic factor binding	Hs	molecular function	138	1.74e-34
brain-derived neurotrophic factor-activated receptor activity	Hs	molecular function	138	1.74e-34
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	Hs	molecular function	178	8.08e-48

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	6.7E-44
protein tyrosine kinase activity	SMART	molecular function	1.9E-13
ATP binding	ProSiteProfiles	molecular function	20.414
protein phosphorylation	Pfam	biological process	6.7E-44